Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales

Epigenetic change is considered relatively unstable and short‐lived, raising questions of its contribution to long‐term adaptive potential. However, epigenetic modifications can accumulate in the presence of environmental stress, resulting in beneficial epigenetic memories where environments are cha...

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Autores principales: Kort, Hanne de, Panis, Bartholomeus, Deforce, Dieter, Nieuwerburgh, Filip van, Honnay, Ollivier
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2020
Materias:
Acceso en línea:https://hdl.handle.net/10568/110242
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author Kort, Hanne de
Panis, Bartholomeus
Deforce, Dieter
Nieuwerburgh, Filip van
Honnay, Ollivier
author_browse Deforce, Dieter
Honnay, Ollivier
Kort, Hanne de
Nieuwerburgh, Filip van
Panis, Bartholomeus
author_facet Kort, Hanne de
Panis, Bartholomeus
Deforce, Dieter
Nieuwerburgh, Filip van
Honnay, Ollivier
author_sort Kort, Hanne de
collection Repository of Agricultural Research Outputs (CGSpace)
description Epigenetic change is considered relatively unstable and short‐lived, raising questions of its contribution to long‐term adaptive potential. However, epigenetic modifications can accumulate in the presence of environmental stress, resulting in beneficial epigenetic memories where environments are challenging. Diverging epigenetic memories have been observed across large spatial scales, and can persist through multiple generations. It is unknown, however, to what extent epigenetic variation contributes to fine‐scale population structure and evolution. We compared DNA methylation patterns between a steep, altitudinal gradient (<2 km) and a wide spatial gradient (>500 km) using whole genome bisulphite sequencing data from 30 Fragaria vesca plants germinated and grown in controlled conditions. To assess the stability of spatial epigenetic variation in the presence of an environmental stressor, we applied acute drought stress to part of the plants and quantified drought‐induced changes in DNA methylation signatures. We find that epigenetic memories and genomic islands of epigenetic divergence arise even at fine spatial scale, and that distinct spatial scales are featured by distinct epigenetic patterns. For example, demethylation of transposable elements consistently occurred at the large but not the fine spatial scale, while methylation differentiation for most biological processes were shared between spatial scales. Acute drought stress did not result in significant epigenetic differentiation. Our results indicate that population history, rather than short‐term environmental stress, plays a dominant role in shaping epigenetic signatures. Specifically, repeated historical stress levels associated with heterogeneous environmental conditions may be required for acquiring a stable epigenetic memory and for coping with future environmental change.
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spelling CGSpace1102422024-09-09T10:04:48Z Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales Kort, Hanne de Panis, Bartholomeus Deforce, Dieter Nieuwerburgh, Filip van Honnay, Ollivier epigenetics plant population environmental factors epigenético población vegetal factores ambientales genetics Epigenetic change is considered relatively unstable and short‐lived, raising questions of its contribution to long‐term adaptive potential. However, epigenetic modifications can accumulate in the presence of environmental stress, resulting in beneficial epigenetic memories where environments are challenging. Diverging epigenetic memories have been observed across large spatial scales, and can persist through multiple generations. It is unknown, however, to what extent epigenetic variation contributes to fine‐scale population structure and evolution. We compared DNA methylation patterns between a steep, altitudinal gradient (<2 km) and a wide spatial gradient (>500 km) using whole genome bisulphite sequencing data from 30 Fragaria vesca plants germinated and grown in controlled conditions. To assess the stability of spatial epigenetic variation in the presence of an environmental stressor, we applied acute drought stress to part of the plants and quantified drought‐induced changes in DNA methylation signatures. We find that epigenetic memories and genomic islands of epigenetic divergence arise even at fine spatial scale, and that distinct spatial scales are featured by distinct epigenetic patterns. For example, demethylation of transposable elements consistently occurred at the large but not the fine spatial scale, while methylation differentiation for most biological processes were shared between spatial scales. Acute drought stress did not result in significant epigenetic differentiation. Our results indicate that population history, rather than short‐term environmental stress, plays a dominant role in shaping epigenetic signatures. Specifically, repeated historical stress levels associated with heterogeneous environmental conditions may be required for acquiring a stable epigenetic memory and for coping with future environmental change. 2020-12 2020-11-19T15:33:08Z 2020-11-19T15:33:08Z Journal Article https://hdl.handle.net/10568/110242 en Limited Access Wiley De Kort, H.; Panis, B.; Deforce, D.; Van Nieuwerburgh, F.; Honnay, O. (2020) Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales. Molecular Ecology, Online first paper (15 October 2020). ISSN: 0962-1083
spellingShingle epigenetics
plant population
environmental factors
epigenético
población vegetal
factores ambientales
genetics
Kort, Hanne de
Panis, Bartholomeus
Deforce, Dieter
Nieuwerburgh, Filip van
Honnay, Ollivier
Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title_full Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title_fullStr Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title_full_unstemmed Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title_short Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales
title_sort ecological divergence of wild strawberry dna methylation patterns at distinct spatial scales
topic epigenetics
plant population
environmental factors
epigenético
población vegetal
factores ambientales
genetics
url https://hdl.handle.net/10568/110242
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