Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication
More people globally depend on the water buffalo than any other domesticated species, and as the most closely related domesticated species to cattle they can provide important insights into the shared evolutionary basis of domestication. Here, we sequence the genomes of 79 water buffalo across seven...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Springer
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/110022 |
| _version_ | 1855543041300889600 |
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| author | Dutta, P. Talenti, A. Young, R. Jayaraman, S. Callaby, R. Jadhav, S.K. Dhanikachalam, V. Manikandan, M. Biswa, B.B. Low, W.Y. Williams, J.L. Cook, Elizabeth A.J. Toye, Philip G. Wall, E. Djikeng, Appolinaire Marshall, Karen Archibald, A.L. Gokhale, S. Kumar, S. Hume, D.A. Prendergast, J.G.D. |
| author_browse | Archibald, A.L. Biswa, B.B. Callaby, R. Cook, Elizabeth A.J. Dhanikachalam, V. Djikeng, Appolinaire Dutta, P. Gokhale, S. Hume, D.A. Jadhav, S.K. Jayaraman, S. Kumar, S. Low, W.Y. Manikandan, M. Marshall, Karen Prendergast, J.G.D. Talenti, A. Toye, Philip G. Wall, E. Williams, J.L. Young, R. |
| author_facet | Dutta, P. Talenti, A. Young, R. Jayaraman, S. Callaby, R. Jadhav, S.K. Dhanikachalam, V. Manikandan, M. Biswa, B.B. Low, W.Y. Williams, J.L. Cook, Elizabeth A.J. Toye, Philip G. Wall, E. Djikeng, Appolinaire Marshall, Karen Archibald, A.L. Gokhale, S. Kumar, S. Hume, D.A. Prendergast, J.G.D. |
| author_sort | Dutta, P. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | More people globally depend on the water buffalo than any other domesticated species, and as the most closely related domesticated species to cattle they can provide important insights into the shared evolutionary basis of domestication. Here, we sequence the genomes of 79 water buffalo across seven breeds and compare patterns of between breed selective sweeps with those seen for 294 cattle genomes representing 13 global breeds. The genomic regions under selection between cattle breeds significantly overlap regions linked to stature in human genetic studies, with a disproportionate number of these loci also shown to be under selection between water buffalo breeds. Investigation of potential functional variants in the water buffalo genome identifies a rare example of convergent domestication down to the same mutation having independently occurred and been selected for across domesticated species. Cross-species comparisons of recent selective sweeps can consequently help identify and refine important loci linked to domestication. |
| format | Journal Article |
| id | CGSpace110022 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace1100222024-01-12T10:00:54Z Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication Dutta, P. Talenti, A. Young, R. Jayaraman, S. Callaby, R. Jadhav, S.K. Dhanikachalam, V. Manikandan, M. Biswa, B.B. Low, W.Y. Williams, J.L. Cook, Elizabeth A.J. Toye, Philip G. Wall, E. Djikeng, Appolinaire Marshall, Karen Archibald, A.L. Gokhale, S. Kumar, S. Hume, D.A. Prendergast, J.G.D. cattle breeds genomes animal breeding genetics water buffaloes More people globally depend on the water buffalo than any other domesticated species, and as the most closely related domesticated species to cattle they can provide important insights into the shared evolutionary basis of domestication. Here, we sequence the genomes of 79 water buffalo across seven breeds and compare patterns of between breed selective sweeps with those seen for 294 cattle genomes representing 13 global breeds. The genomic regions under selection between cattle breeds significantly overlap regions linked to stature in human genetic studies, with a disproportionate number of these loci also shown to be under selection between water buffalo breeds. Investigation of potential functional variants in the water buffalo genome identifies a rare example of convergent domestication down to the same mutation having independently occurred and been selected for across domesticated species. Cross-species comparisons of recent selective sweeps can consequently help identify and refine important loci linked to domestication. 2020-09-21 2020-10-30T08:24:42Z 2020-10-30T08:24:42Z Journal Article https://hdl.handle.net/10568/110022 en Open Access Springer Dutta, P., Talenti, A., Young, R., Jayaraman, S., Callaby, R., Jadhav, S.K., Dhanikachalam, V., Manikandan, M., Biswa, B.B., Low, W.Y., Williams, J.L., Cook, E., Toye, P., Wall, E., Djikeng, A., Marshall, K., Archibald, A.L., Gokhale, S., Kumar, S., Hume, D.A. and Prendergast, J.G.D. 2020. Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication. Nature Communications 11(1):4739. |
| spellingShingle | cattle breeds genomes animal breeding genetics water buffaloes Dutta, P. Talenti, A. Young, R. Jayaraman, S. Callaby, R. Jadhav, S.K. Dhanikachalam, V. Manikandan, M. Biswa, B.B. Low, W.Y. Williams, J.L. Cook, Elizabeth A.J. Toye, Philip G. Wall, E. Djikeng, Appolinaire Marshall, Karen Archibald, A.L. Gokhale, S. Kumar, S. Hume, D.A. Prendergast, J.G.D. Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title | Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title_full | Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title_fullStr | Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title_full_unstemmed | Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title_short | Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| title_sort | whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication |
| topic | cattle breeds genomes animal breeding genetics water buffaloes |
| url | https://hdl.handle.net/10568/110022 |
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