Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018

On the last week of May of 2018, a community-based syndromic surveillance system detected mass abortions and deaths of young livestock in northeastern Kenya. Two weeks later, Rift Valley fever (RVF) was confirmed in humans presenting with febrile illness and hemorrhagic syndrome in the same region....

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Main Authors: Hassan, A., Muturi, M., Mwatondo, A., Omolo, J., Bett, Bernard K., Gikundi, S., Konongoi, L., Ofula, V., Makayotto, L., Kasiti, J., Oele, E., Onyango, C., Gura, Z., Njenga, K., Munyua, P.
Format: Journal Article
Language:Inglés
Published: American Society of Tropical Medicine and Hygiene 2020
Subjects:
Online Access:https://hdl.handle.net/10568/109979
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author Hassan, A.
Muturi, M.
Mwatondo, A.
Omolo, J.
Bett, Bernard K.
Gikundi, S.
Konongoi, L.
Ofula, V.
Makayotto, L.
Kasiti, J.
Oele, E.
Onyango, C.
Gura, Z.
Njenga, K.
Munyua, P.
author_browse Bett, Bernard K.
Gikundi, S.
Gura, Z.
Hassan, A.
Kasiti, J.
Konongoi, L.
Makayotto, L.
Munyua, P.
Muturi, M.
Mwatondo, A.
Njenga, K.
Oele, E.
Ofula, V.
Omolo, J.
Onyango, C.
author_facet Hassan, A.
Muturi, M.
Mwatondo, A.
Omolo, J.
Bett, Bernard K.
Gikundi, S.
Konongoi, L.
Ofula, V.
Makayotto, L.
Kasiti, J.
Oele, E.
Onyango, C.
Gura, Z.
Njenga, K.
Munyua, P.
author_sort Hassan, A.
collection Repository of Agricultural Research Outputs (CGSpace)
description On the last week of May of 2018, a community-based syndromic surveillance system detected mass abortions and deaths of young livestock in northeastern Kenya. Two weeks later, Rift Valley fever (RVF) was confirmed in humans presenting with febrile illness and hemorrhagic syndrome in the same region. A joint animal and human response team carried out an investigation to characterize the outbreak and identify drivers of disease transmission. Here, we describe the outbreak investigation and findings. A total of 106 human cases were identified in the months of May and June 2018: 92% (98) and 8% (8) of these cases occurring in the northern and western regions of Kenya, respectively. Seventy-six (72%) were probable cases, and 30 (28%) were laboratory confirmed by ELISA and/or PCR. Among the confirmed cases, the median age was 27.5 years (interquartile range = 20), and 60% (18) were males. Overall, the case fatality rate was 7% (n = 8). The majority of the confirmed cases, 19 (63%), reported contact with livestock during slaughter and consumption of meat from sick animals. All confirmed cases had fever, 40% (12) presented with hemorrhagic syndrome, and 23% (7) presented with jaundice. Forty-three livestock herds with at least one suspect and/or confirmed animal case were identified. Death of young animals was reported in 93% (40) and abortions in 84% (36) of livestock herds. The outbreak is indicative of the emergence potential of RVF in traditionally high- and low-risk areas and the risk posed by zoonosis to livestock keepers.
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spelling CGSpace1099792025-12-08T09:54:28Z Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018 Hassan, A. Muturi, M. Mwatondo, A. Omolo, J. Bett, Bernard K. Gikundi, S. Konongoi, L. Ofula, V. Makayotto, L. Kasiti, J. Oele, E. Onyango, C. Gura, Z. Njenga, K. Munyua, P. zoonoses rift valley fever epidemiology livestock health animal diseases On the last week of May of 2018, a community-based syndromic surveillance system detected mass abortions and deaths of young livestock in northeastern Kenya. Two weeks later, Rift Valley fever (RVF) was confirmed in humans presenting with febrile illness and hemorrhagic syndrome in the same region. A joint animal and human response team carried out an investigation to characterize the outbreak and identify drivers of disease transmission. Here, we describe the outbreak investigation and findings. A total of 106 human cases were identified in the months of May and June 2018: 92% (98) and 8% (8) of these cases occurring in the northern and western regions of Kenya, respectively. Seventy-six (72%) were probable cases, and 30 (28%) were laboratory confirmed by ELISA and/or PCR. Among the confirmed cases, the median age was 27.5 years (interquartile range = 20), and 60% (18) were males. Overall, the case fatality rate was 7% (n = 8). The majority of the confirmed cases, 19 (63%), reported contact with livestock during slaughter and consumption of meat from sick animals. All confirmed cases had fever, 40% (12) presented with hemorrhagic syndrome, and 23% (7) presented with jaundice. Forty-three livestock herds with at least one suspect and/or confirmed animal case were identified. Death of young animals was reported in 93% (40) and abortions in 84% (36) of livestock herds. The outbreak is indicative of the emergence potential of RVF in traditionally high- and low-risk areas and the risk posed by zoonosis to livestock keepers. 2020-10-07 2020-10-26T13:14:14Z 2020-10-26T13:14:14Z Journal Article https://hdl.handle.net/10568/109979 en Open Access American Society of Tropical Medicine and Hygiene Hassan, A., Muturi, M., Mwatondo, A., Omolo, J., Bett, B., Gikundi, S., Konongoi, L., Ofula, V., Makayotto, L., Kasiti, J., Oele, E., Onyango, C., Gura, Z., Njenga, K. and Munyua, P. 2020. Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018. American Journal of Tropical Medicine and Hygiene 103(4): 1649–1655.
spellingShingle zoonoses
rift valley fever
epidemiology
livestock
health
animal diseases
Hassan, A.
Muturi, M.
Mwatondo, A.
Omolo, J.
Bett, Bernard K.
Gikundi, S.
Konongoi, L.
Ofula, V.
Makayotto, L.
Kasiti, J.
Oele, E.
Onyango, C.
Gura, Z.
Njenga, K.
Munyua, P.
Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title_full Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title_fullStr Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title_full_unstemmed Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title_short Epidemiological investigation of a Rift Valley fever outbreak in humans and livestock in Kenya, 2018
title_sort epidemiological investigation of a rift valley fever outbreak in humans and livestock in kenya 2018
topic zoonoses
rift valley fever
epidemiology
livestock
health
animal diseases
url https://hdl.handle.net/10568/109979
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