Improved antibacterial efficiency of inhaled thiamphenicol dry powders: Mathematical modelling of in vitro dissolution kinetic and in vitro antibacterial efficacy

Thiamphenicol (TAP) is reported to be effective against many respiratory pathogens including methicillin-resistant Staphylococcus aureus (MRSA). However, its poor solubility in water remains as one of the obstacles hindering the preparation of inhalable TAP formulations. The aim of this study was to...

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Bibliographic Details
Main Authors: Wang, J., Grégoire, N., Marchand, S., Kutter, J.P., Mu, H., Moodley, Arshnee, Couet, W., Yang, M.
Format: Journal Article
Language:Inglés
Published: Elsevier 2020
Subjects:
Online Access:https://hdl.handle.net/10568/108766

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