Methyl phenlactonoates are efficient strigolactone analogs with simple structure

Strigolactones (SLs) are a new class of phytohormones that also act as germination stimulants for root parasitic plants, such as Striga spp., and as branching factors for symbiotic arbuscular mycorrhizal fungi. Sources for natural SLs are very limited. Hence, efficient and simple SL analogs are need...

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Autores principales: Jamil, M., Kountche, B.A., Haider, I., Guo, X., Ntui, V.O., Jia, K.P., Ali, S., Hameed, U.S., Nakamura, H., Lyu, Y., Jiang, K., Hirabayashi, K., Tanokura, M., Arold, S.T., Asami, T., Al-Babili, S.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://hdl.handle.net/10568/108199
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author Jamil, M.
Kountche, B.A.
Haider, I.
Guo, X.
Ntui, V.O.
Jia, K.P.
Ali, S.
Hameed, U.S.
Nakamura, H.
Lyu, Y.
Jiang, K.
Hirabayashi, K.
Tanokura, M.
Arold, S.T.
Asami, T.
Al-Babili, S.
author_browse Al-Babili, S.
Ali, S.
Arold, S.T.
Asami, T.
Guo, X.
Haider, I.
Hameed, U.S.
Hirabayashi, K.
Jamil, M.
Jia, K.P.
Jiang, K.
Kountche, B.A.
Lyu, Y.
Nakamura, H.
Ntui, V.O.
Tanokura, M.
author_facet Jamil, M.
Kountche, B.A.
Haider, I.
Guo, X.
Ntui, V.O.
Jia, K.P.
Ali, S.
Hameed, U.S.
Nakamura, H.
Lyu, Y.
Jiang, K.
Hirabayashi, K.
Tanokura, M.
Arold, S.T.
Asami, T.
Al-Babili, S.
author_sort Jamil, M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Strigolactones (SLs) are a new class of phytohormones that also act as germination stimulants for root parasitic plants, such as Striga spp., and as branching factors for symbiotic arbuscular mycorrhizal fungi. Sources for natural SLs are very limited. Hence, efficient and simple SL analogs are needed for elucidating SL-related biological processes as well as for agricultural applications. Based on the structure of the non-canonical SL methyl carlactonoate, we developed a new, easy to synthesize series of analogs, termed methyl phenlactonoates (MPs), evaluated their efficacy in exerting different SL functions, and determined their affinity for SL receptors from rice and Striga hermonthica. Most of the MPs showed considerable activity in regulating plant architecture, triggering leaf senescence, and inducing parasitic seed germination. Moreover, some MPs outperformed GR24, a widely used SL analog with a complex structure, in exerting particular SL functions, such as modulating Arabidopsis roots architecture and inhibiting rice tillering. Thus, MPs will help in elucidating the functions of SLs and are promising candidates for agricultural applications. Moreover, MPs demonstrate that slight structural modifications clearly impact the efficiency in exerting particular SL functions, indicating that structural diversity of natural SLs may mirror a functional specificity.
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spelling CGSpace1081992023-12-08T19:36:04Z Methyl phenlactonoates are efficient strigolactone analogs with simple structure Jamil, M. Kountche, B.A. Haider, I. Guo, X. Ntui, V.O. Jia, K.P. Ali, S. Hameed, U.S. Nakamura, H. Lyu, Y. Jiang, K. Hirabayashi, K. Tanokura, M. Arold, S.T. Asami, T. Al-Babili, S. striga hermonthica tillering Strigolactones (SLs) are a new class of phytohormones that also act as germination stimulants for root parasitic plants, such as Striga spp., and as branching factors for symbiotic arbuscular mycorrhizal fungi. Sources for natural SLs are very limited. Hence, efficient and simple SL analogs are needed for elucidating SL-related biological processes as well as for agricultural applications. Based on the structure of the non-canonical SL methyl carlactonoate, we developed a new, easy to synthesize series of analogs, termed methyl phenlactonoates (MPs), evaluated their efficacy in exerting different SL functions, and determined their affinity for SL receptors from rice and Striga hermonthica. Most of the MPs showed considerable activity in regulating plant architecture, triggering leaf senescence, and inducing parasitic seed germination. Moreover, some MPs outperformed GR24, a widely used SL analog with a complex structure, in exerting particular SL functions, such as modulating Arabidopsis roots architecture and inhibiting rice tillering. Thus, MPs will help in elucidating the functions of SLs and are promising candidates for agricultural applications. Moreover, MPs demonstrate that slight structural modifications clearly impact the efficiency in exerting particular SL functions, indicating that structural diversity of natural SLs may mirror a functional specificity. 2018-04-23 2020-05-09T12:47:00Z 2020-05-09T12:47:00Z Journal Article https://hdl.handle.net/10568/108199 en Open Access Oxford University Press Jamil, M., Kountche, B.A., Haider, I., Guo, X., Ntui, V.O., Jia, K.P., ... & Jiang, K. (2018). Methyl phenlactonoates are efficient strigolactone analogs with simple structure. Journal of experimental botany, 69(9), 2319-2331.
spellingShingle striga hermonthica
tillering
Jamil, M.
Kountche, B.A.
Haider, I.
Guo, X.
Ntui, V.O.
Jia, K.P.
Ali, S.
Hameed, U.S.
Nakamura, H.
Lyu, Y.
Jiang, K.
Hirabayashi, K.
Tanokura, M.
Arold, S.T.
Asami, T.
Al-Babili, S.
Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title_full Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title_fullStr Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title_full_unstemmed Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title_short Methyl phenlactonoates are efficient strigolactone analogs with simple structure
title_sort methyl phenlactonoates are efficient strigolactone analogs with simple structure
topic striga hermonthica
tillering
url https://hdl.handle.net/10568/108199
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