Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers

Rwanda has about 4.5 million of indigenous chicken (IC) that are very low in productivity. To initiate any genetic improvement programme, IC needs to be accurately characterized. The key purpose of this study was to ascertain the genetic diversity of IC in Rwanda using microsatellite markers. Blood...

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Autores principales: Habimana, Richard, Okeno, Tobias O., Ngeno, Kiplangat, Mboumba, Sylvere, Assami, Pauline, Gbotto, Anique A., Tiambo, Christian K., Nishimwe, Kizito, Mahoro, Janvier, Yao, Nasser
Formato: Journal Article
Lenguaje:Inglés
Publicado: Public Library of Science 2020
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Acceso en línea:https://hdl.handle.net/10568/107967
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author Habimana, Richard
Okeno, Tobias O.
Ngeno, Kiplangat
Mboumba, Sylvere
Assami, Pauline
Gbotto, Anique A.
Tiambo, Christian K.
Nishimwe, Kizito
Mahoro, Janvier
Yao, Nasser
author_browse Assami, Pauline
Gbotto, Anique A.
Habimana, Richard
Mahoro, Janvier
Mboumba, Sylvere
Ngeno, Kiplangat
Nishimwe, Kizito
Okeno, Tobias O.
Tiambo, Christian K.
Yao, Nasser
author_facet Habimana, Richard
Okeno, Tobias O.
Ngeno, Kiplangat
Mboumba, Sylvere
Assami, Pauline
Gbotto, Anique A.
Tiambo, Christian K.
Nishimwe, Kizito
Mahoro, Janvier
Yao, Nasser
author_sort Habimana, Richard
collection Repository of Agricultural Research Outputs (CGSpace)
description Rwanda has about 4.5 million of indigenous chicken (IC) that are very low in productivity. To initiate any genetic improvement programme, IC needs to be accurately characterized. The key purpose of this study was to ascertain the genetic diversity of IC in Rwanda using microsatellite markers. Blood samples of IC sampled from 5 agro-ecological zones were collected from which DNA was extracted, amplified by PCR and genotyped using 28 microsatellite markers. A total of 325 (313 indigenous and 12 exotic) chickens were genotyped and revealed a total number of 305 alleles varying between 2 and 22 with a mean of 10.89 per locus. One hundred eighty-six (186) distinct alleles and 60 private alleles were also observed. The frequency of private alleles was highest in samples from the Eastern region, whereas those from the North West had the lowest. The influx of genes was lower in the Eastern agro-ecological zone than the North West. The mean observed heterozygosity was 0.6155, whereas the average expected heterozygosity was 0.688. The overall inbreeding coefficient among the population was 0.040. Divergence from the Hardy-Weinberg equilibrium was significant (p<0.05) in 90% of loci in all the populations. The analysis of molecular variance revealed that about 92% of the total variation originated from variation within populations. Additionally, the study demonstrated that IC in Rwanda could be clustered into four gene groups. In conclusion, there was considerable genetic diversity in IC in Rwanda, which represents a crucial genetic resource that can be conserved or optimized through genetic improvement.
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spelling CGSpace1079672025-01-27T15:00:52Z Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers Habimana, Richard Okeno, Tobias O. Ngeno, Kiplangat Mboumba, Sylvere Assami, Pauline Gbotto, Anique A. Tiambo, Christian K. Nishimwe, Kizito Mahoro, Janvier Yao, Nasser animal breeding genetics chickens indigenous breeds livestock poultry Rwanda has about 4.5 million of indigenous chicken (IC) that are very low in productivity. To initiate any genetic improvement programme, IC needs to be accurately characterized. The key purpose of this study was to ascertain the genetic diversity of IC in Rwanda using microsatellite markers. Blood samples of IC sampled from 5 agro-ecological zones were collected from which DNA was extracted, amplified by PCR and genotyped using 28 microsatellite markers. A total of 325 (313 indigenous and 12 exotic) chickens were genotyped and revealed a total number of 305 alleles varying between 2 and 22 with a mean of 10.89 per locus. One hundred eighty-six (186) distinct alleles and 60 private alleles were also observed. The frequency of private alleles was highest in samples from the Eastern region, whereas those from the North West had the lowest. The influx of genes was lower in the Eastern agro-ecological zone than the North West. The mean observed heterozygosity was 0.6155, whereas the average expected heterozygosity was 0.688. The overall inbreeding coefficient among the population was 0.040. Divergence from the Hardy-Weinberg equilibrium was significant (p<0.05) in 90% of loci in all the populations. The analysis of molecular variance revealed that about 92% of the total variation originated from variation within populations. Additionally, the study demonstrated that IC in Rwanda could be clustered into four gene groups. In conclusion, there was considerable genetic diversity in IC in Rwanda, which represents a crucial genetic resource that can be conserved or optimized through genetic improvement. 2020-04-02 2020-04-11T17:48:21Z 2020-04-11T17:48:21Z Journal Article https://hdl.handle.net/10568/107967 en Open Access Public Library of Science Habimana, R., Okeno, T.O., Ngeno, K., Mboumba, S., Assami, P., Gbotto, A.A., Tiambo, C.K., Nishimwe, K., Mahoro, J. and Yao, N. 2020. Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers. PLoS ONE 15(4): e0225084.
spellingShingle animal breeding
genetics
chickens
indigenous breeds
livestock
poultry
Habimana, Richard
Okeno, Tobias O.
Ngeno, Kiplangat
Mboumba, Sylvere
Assami, Pauline
Gbotto, Anique A.
Tiambo, Christian K.
Nishimwe, Kizito
Mahoro, Janvier
Yao, Nasser
Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title_full Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title_fullStr Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title_full_unstemmed Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title_short Genetic diversity and population structure of indigenous chicken in Rwanda using microsatellite markers
title_sort genetic diversity and population structure of indigenous chicken in rwanda using microsatellite markers
topic animal breeding
genetics
chickens
indigenous breeds
livestock
poultry
url https://hdl.handle.net/10568/107967
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