Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages

Assembly of a training population (TP) is an important component of effective genomic selection‐based breeding programs. In this study, we examined the power of diverse germplasm assembled from two cassava (Manihot esculenta Crantz) breeding programs in Tanzania at different breeding stages to predi...

Descripción completa

Detalles Bibliográficos
Autores principales: Somo, M., Kulembeka, H., Mtunda, K., Mrema, E., Salum, K., Wolfe, M.D., Rabbi, Ismail Y., Egesi, Chiedozie N., Kawuki, R.S., Ozimati, A., Lozano, R., Jannink, Jean-Luc
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2019
Materias:
Acceso en línea:https://hdl.handle.net/10568/107742
_version_ 1855524445101228032
author Somo, M.
Kulembeka, H.
Mtunda, K.
Mrema, E.
Salum, K.
Wolfe, M.D.
Rabbi, Ismail Y.
Egesi, Chiedozie N.
Kawuki, R.S.
Ozimati, A.
Lozano, R.
Jannink, Jean-Luc
author_browse Egesi, Chiedozie N.
Jannink, Jean-Luc
Kawuki, R.S.
Kulembeka, H.
Lozano, R.
Mrema, E.
Mtunda, K.
Ozimati, A.
Rabbi, Ismail Y.
Salum, K.
Somo, M.
Wolfe, M.D.
author_facet Somo, M.
Kulembeka, H.
Mtunda, K.
Mrema, E.
Salum, K.
Wolfe, M.D.
Rabbi, Ismail Y.
Egesi, Chiedozie N.
Kawuki, R.S.
Ozimati, A.
Lozano, R.
Jannink, Jean-Luc
author_sort Somo, M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Assembly of a training population (TP) is an important component of effective genomic selection‐based breeding programs. In this study, we examined the power of diverse germplasm assembled from two cassava (Manihot esculenta Crantz) breeding programs in Tanzania at different breeding stages to predict traits and discover quantitative trait loci (QTL). This is the first genomic selection and genome‐wide association study (GWAS) on Tanzanian cassava data. We detected QTL associated with cassava mosaic disease (CMD) resistance on chromosomes 12 and 16; QTL conferring resistance to cassava brown streak disease (CBSD) on chromosomes 9 and 11; and QTL on chromosomes 2, 3, 8, and 10 associated with resistance to CBSD for root necrosis. We detected a QTL on chromosome 4 and two QTL on chromosome 12 conferring dual resistance to CMD and CBSD. The use of clones in the same stage to construct TPs provided higher trait prediction accuracy than TPs with a mixture of clones from multiple breeding stages. Moreover, clones in the early breeding stage provided more reliable trait prediction accuracy and are better candidates for constructing a TP. Although larger TP sizes have been associated with improved accuracy, in this study, adding clones from Kibaha to those from Ukiriguru and vice versa did not improve the prediction accuracy of either population. Including the Ugandan TP in either population did not improve trait prediction accuracy. This study applied genomic prediction to understand the implications of constructing TP from clones at different breeding stages pooled from different locations on trait accuracy.
format Journal Article
id CGSpace107742
institution CGIAR Consortium
language Inglés
publishDate 2019
publishDateRange 2019
publishDateSort 2019
publisher Wiley
publisherStr Wiley
record_format dspace
spelling CGSpace1077422025-11-11T10:16:16Z Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages Somo, M. Kulembeka, H. Mtunda, K. Mrema, E. Salum, K. Wolfe, M.D. Rabbi, Ismail Y. Egesi, Chiedozie N. Kawuki, R.S. Ozimati, A. Lozano, R. Jannink, Jean-Luc cassava plant breeding genotypes african cassava mosaic virus quantitative trait loci tanzania uganda east africa Assembly of a training population (TP) is an important component of effective genomic selection‐based breeding programs. In this study, we examined the power of diverse germplasm assembled from two cassava (Manihot esculenta Crantz) breeding programs in Tanzania at different breeding stages to predict traits and discover quantitative trait loci (QTL). This is the first genomic selection and genome‐wide association study (GWAS) on Tanzanian cassava data. We detected QTL associated with cassava mosaic disease (CMD) resistance on chromosomes 12 and 16; QTL conferring resistance to cassava brown streak disease (CBSD) on chromosomes 9 and 11; and QTL on chromosomes 2, 3, 8, and 10 associated with resistance to CBSD for root necrosis. We detected a QTL on chromosome 4 and two QTL on chromosome 12 conferring dual resistance to CMD and CBSD. The use of clones in the same stage to construct TPs provided higher trait prediction accuracy than TPs with a mixture of clones from multiple breeding stages. Moreover, clones in the early breeding stage provided more reliable trait prediction accuracy and are better candidates for constructing a TP. Although larger TP sizes have been associated with improved accuracy, in this study, adding clones from Kibaha to those from Ukiriguru and vice versa did not improve the prediction accuracy of either population. Including the Ugandan TP in either population did not improve trait prediction accuracy. This study applied genomic prediction to understand the implications of constructing TP from clones at different breeding stages pooled from different locations on trait accuracy. 2019-12-11 2020-03-13T10:10:12Z 2020-03-13T10:10:12Z Journal Article https://hdl.handle.net/10568/107742 en Open Access application/pdf Wiley Somo, M., Kulembeka, H., Mtunda, K., Mrema, E., Salum, K., Wolfe, M.D., ... & Jannink, J. (2020). Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages. Crop Science, 60, 896–913.
spellingShingle cassava
plant breeding
genotypes
african cassava mosaic virus
quantitative trait loci
tanzania
uganda
east africa
Somo, M.
Kulembeka, H.
Mtunda, K.
Mrema, E.
Salum, K.
Wolfe, M.D.
Rabbi, Ismail Y.
Egesi, Chiedozie N.
Kawuki, R.S.
Ozimati, A.
Lozano, R.
Jannink, Jean-Luc
Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title_full Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title_fullStr Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title_full_unstemmed Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title_short Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
title_sort genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages
topic cassava
plant breeding
genotypes
african cassava mosaic virus
quantitative trait loci
tanzania
uganda
east africa
url https://hdl.handle.net/10568/107742
work_keys_str_mv AT somom genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT kulembekah genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT mtundak genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT mremae genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT salumk genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT wolfemd genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT rabbiismaily genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT egesichiedozien genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT kawukirs genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT ozimatia genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT lozanor genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages
AT janninkjeanluc genomicpredictionandquantitativetraitlocusdiscoveryinacassavatrainingpopulationconstructedfrommultiplebreedingstages