Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows
The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Alb...
| Autores principales: | , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Springer
2020
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/106588 |
| _version_ | 1855514397105979392 |
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| author | Saltzmann, J. Xu, Y. Gong, Y.Y. Kersten, S. Danicke, S. Routledge, M.N. Lindahl, Johanna F. |
| author_browse | Danicke, S. Gong, Y.Y. Kersten, S. Lindahl, Johanna F. Routledge, M.N. Saltzmann, J. Xu, Y. |
| author_facet | Saltzmann, J. Xu, Y. Gong, Y.Y. Kersten, S. Danicke, S. Routledge, M.N. Lindahl, Johanna F. |
| author_sort | Saltzmann, J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Albumin adduct data were compared with aflatoxin M1 (AFM1) levels in corresponding milk samples from these cows. The concentration ranged from < LOD to 487.9 pg/mL for AFM1 and < LOD and 96.3 pg/mg for aflatoxin-albumin. This study indicates that aflatoxin-albumin adducts could be used as a measure of chronic aflatoxin exposure in dairy cattle. |
| format | Journal Article |
| id | CGSpace106588 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace1065882025-12-08T09:54:28Z Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows Saltzmann, J. Xu, Y. Gong, Y.Y. Kersten, S. Danicke, S. Routledge, M.N. Lindahl, Johanna F. aflatoxins cattle dairy cattle health livestock toxicology microbiology biotechnology The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Albumin adduct data were compared with aflatoxin M1 (AFM1) levels in corresponding milk samples from these cows. The concentration ranged from < LOD to 487.9 pg/mL for AFM1 and < LOD and 96.3 pg/mg for aflatoxin-albumin. This study indicates that aflatoxin-albumin adducts could be used as a measure of chronic aflatoxin exposure in dairy cattle. 2020-05 2020-01-16T08:18:12Z 2020-01-16T08:18:12Z Journal Article https://hdl.handle.net/10568/106588 en Limited Access Springer Saltzmann, J., Xu, Y., Gong, Y.Y., Lindahl, J., Kersten, S., Dänicke, S. and Routledge, M.N. 2020. Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows. Mycotoxin Research 36(2): 207–211. |
| spellingShingle | aflatoxins cattle dairy cattle health livestock toxicology microbiology biotechnology Saltzmann, J. Xu, Y. Gong, Y.Y. Kersten, S. Danicke, S. Routledge, M.N. Lindahl, Johanna F. Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title | Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title_full | Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title_fullStr | Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title_full_unstemmed | Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title_short | Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows |
| title_sort | preliminary study on the relationship between aflatoxin bovine serum albumin adducts in blood and aflatoxin m1 levels in milk of dairy cows |
| topic | aflatoxins cattle dairy cattle health livestock toxicology microbiology biotechnology |
| url | https://hdl.handle.net/10568/106588 |
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