Attenuation of a pathogenic Mycoplasma strain by modification of the obg gene by using synthetic biology approaches

Mycoplasma species are responsible for several economically significant livestock diseases for which there is a need for new and improved vaccines. Most of the existing mycoplasma vaccines are attenuated strains that have been empirically obtained by serial passages or by chemical mutagenesis. The r...

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Bibliographic Details

Main Authors:	Lartigue, C., Valverde Timana, Y., Labroussaa, F., Schieck, Elise G., Liljander, Anne M., Sacchini, Flavio, Posthaus, H., Batailler, B., Sirand-Pugnet, P., Vashee, S., Jores, Joerg, Blanchard, Alain
Format:	Journal Article
Language:	Inglés
Published:	American Society for Microbiology 2019
Subjects:	mycoplasma genomes vaccines research animal diseases pathogenicity
Online Access:	https://hdl.handle.net/10568/106289