Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3

The interferon-induced transmembrane (IFITM) protein family comprises a class of restriction factors widely characterised in humans for their potent antiviral activity. Their biological activity is well documented in several animal species, but their genetic variation and biological mechanism is les...

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Bibliographic Details
Main Authors: Bassano, I., Swee Hoe Ong, Sanz Hernandez, M., Vinkler, M., Kebede, A., Hanotte, Olivier H., Onuigbo, E., Fife, M., Kellam, P.
Format: Journal Article
Language:Inglés
Published: Springer 2019
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Online Access:https://hdl.handle.net/10568/106279

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