Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia

In Zambia, mothers/caregivers feed their children cereal-based complementary foods that are prone to aflatoxin contamination. This study evaluated the relationship between exposure to aflatoxins and the nutritional status of young children. It covered 400 mothers with children aged 6–24 months. Thei...

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Autores principales: Alamu, Emmanuel Oladeji, Gondwe, T., Akello, J., Maziya-Dixon, B.B., Mukanga, M.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Informa UK Limited 2020
Materias:
Acceso en línea:https://hdl.handle.net/10568/105806
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author Alamu, Emmanuel Oladeji
Gondwe, T.
Akello, J.
Maziya-Dixon, B.B.
Mukanga, M.
author_browse Akello, J.
Alamu, Emmanuel Oladeji
Gondwe, T.
Maziya-Dixon, B.B.
Mukanga, M.
author_facet Alamu, Emmanuel Oladeji
Gondwe, T.
Akello, J.
Maziya-Dixon, B.B.
Mukanga, M.
author_sort Alamu, Emmanuel Oladeji
collection Repository of Agricultural Research Outputs (CGSpace)
description In Zambia, mothers/caregivers feed their children cereal-based complementary foods that are prone to aflatoxin contamination. This study evaluated the relationship between exposure to aflatoxins and the nutritional status of young children. It covered 400 mothers with children aged 6–24 months. Their nutritional status assessed by measuring weight and height using standard procedures. Serum samples analysed for aflatoxin B1-lysine (AFB1-lys), a reliable biomarker of aflatoxin exposure. Child sickness and age, exposure to aflatoxin in foods, and albumin-normalised AFB1-lys level were found to be significantly (p < .05) associated with child stunting except for child age that was not significant at p = .05. Children with an increase in the blood serum aflatoxin B1 lysine adduct are more likely to be stunted. These results have shown that dietary exposure to aflatoxin could lead to an increase in serum aflatoxin concentrations, both of which are associated with stunting.
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spelling CGSpace1058062025-01-28T07:08:05Z Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia Alamu, Emmanuel Oladeji Gondwe, T. Akello, J. Maziya-Dixon, B.B. Mukanga, M. aflatoxins food access children nutritional status maize food science In Zambia, mothers/caregivers feed their children cereal-based complementary foods that are prone to aflatoxin contamination. This study evaluated the relationship between exposure to aflatoxins and the nutritional status of young children. It covered 400 mothers with children aged 6–24 months. Their nutritional status assessed by measuring weight and height using standard procedures. Serum samples analysed for aflatoxin B1-lysine (AFB1-lys), a reliable biomarker of aflatoxin exposure. Child sickness and age, exposure to aflatoxin in foods, and albumin-normalised AFB1-lys level were found to be significantly (p < .05) associated with child stunting except for child age that was not significant at p = .05. Children with an increase in the blood serum aflatoxin B1 lysine adduct are more likely to be stunted. These results have shown that dietary exposure to aflatoxin could lead to an increase in serum aflatoxin concentrations, both of which are associated with stunting. 2020-07-03 2019-11-19T10:35:00Z 2019-11-19T10:35:00Z Journal Article https://hdl.handle.net/10568/105806 en Open Access Informa UK Limited Alamu, E.O., Gondwe, T., Akello, J., Maziya-Dixon, B. & Mukanga, M. (2019). Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia. International Journal of Food Sciences and Nutrition, 1-11.
spellingShingle aflatoxins
food access
children
nutritional status
maize
food science
Alamu, Emmanuel Oladeji
Gondwe, T.
Akello, J.
Maziya-Dixon, B.B.
Mukanga, M.
Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title_full Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title_fullStr Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title_full_unstemmed Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title_short Relationship between serum aflatoxin concentrations and the nutritional status of children aged 6-24 months from Zambia
title_sort relationship between serum aflatoxin concentrations and the nutritional status of children aged 6 24 months from zambia
topic aflatoxins
food access
children
nutritional status
maize
food science
url https://hdl.handle.net/10568/105806
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