Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam
Background Leptospirosis is an important zoonotic disease with a global distribution, affecting a wide range of mammalian animals and humans. Japanese encephalitis (JE) virus is the major vector-borne zoonotic disease in the Asia-Pacific region. The main objective of this study was to evaluate the s...
| Autores principales: | , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
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Public Library of Science
2019
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| Acceso en línea: | https://hdl.handle.net/10568/102402 |
| _version_ | 1855539711247908864 |
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| author | Hu Suk Lee To Long Thanh Nguyen Khanh Ly Hung Nguyen-Viet Thakur, Krishna K. Grace, Delia |
| author_browse | Grace, Delia Hu Suk Lee Hung Nguyen-Viet Nguyen Khanh Ly Thakur, Krishna K. To Long Thanh |
| author_facet | Hu Suk Lee To Long Thanh Nguyen Khanh Ly Hung Nguyen-Viet Thakur, Krishna K. Grace, Delia |
| author_sort | Hu Suk Lee |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background Leptospirosis is an important zoonotic disease with a global distribution, affecting a wide range of mammalian animals and humans. Japanese encephalitis (JE) virus is the major vector-borne zoonotic disease in the Asia-Pacific region. The main objective of this study was to evaluate the seroprevalence of serovar-specific Leptospira and JE in swine from 10 provinces in Vietnam. Methods Samples were initially collected for swine influenza surveillance from March to April 2017 at large-scale farms (with at least 50 sows and/or 250 fattening pigs) with pigs that tested positive for influenza in the previous surveillance period (2015–16). Findings A total of 2,000 sera samples were analyzed from 10 provinces. Overall, the seroprevalence of leptospirosis was 21.05% (95% CI: 19.28–22.90) using a cut-off titer of ≥ 1:100. The apparent prevalence of JE was 73.45% (95% CI: 71.46–75.37) while the true prevalence was slightly higher (74.46%, 95% credible interval: 73.73–86.41). We found a relatively high presence of leptospirosis and JE in pigs kept on large farms. Prevalence was comparable with other studies suggesting opportunistic testing of samples collected for other surveillance purposes can be a valuable tool to better understand and prevent the potential transmission of these zoonotic diseases from pigs to people in Vietnam. Conclusion Our study provides evidence to veterinarians and animal health professionals for evidence-based practice such as diagnosis, vaccination and zoonotic control. Further investigation into the possible role of different domestic animals, wildlife species or environmental factors is needed to identify the potential risk factors and transmission routes in Vietnam. |
| format | Journal Article |
| id | CGSpace102402 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Public Library of Science |
| publisherStr | Public Library of Science |
| record_format | dspace |
| spelling | CGSpace1024022023-12-08T19:36:04Z Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam Hu Suk Lee To Long Thanh Nguyen Khanh Ly Hung Nguyen-Viet Thakur, Krishna K. Grace, Delia zoonoses swine disease prevalence Background Leptospirosis is an important zoonotic disease with a global distribution, affecting a wide range of mammalian animals and humans. Japanese encephalitis (JE) virus is the major vector-borne zoonotic disease in the Asia-Pacific region. The main objective of this study was to evaluate the seroprevalence of serovar-specific Leptospira and JE in swine from 10 provinces in Vietnam. Methods Samples were initially collected for swine influenza surveillance from March to April 2017 at large-scale farms (with at least 50 sows and/or 250 fattening pigs) with pigs that tested positive for influenza in the previous surveillance period (2015–16). Findings A total of 2,000 sera samples were analyzed from 10 provinces. Overall, the seroprevalence of leptospirosis was 21.05% (95% CI: 19.28–22.90) using a cut-off titer of ≥ 1:100. The apparent prevalence of JE was 73.45% (95% CI: 71.46–75.37) while the true prevalence was slightly higher (74.46%, 95% credible interval: 73.73–86.41). We found a relatively high presence of leptospirosis and JE in pigs kept on large farms. Prevalence was comparable with other studies suggesting opportunistic testing of samples collected for other surveillance purposes can be a valuable tool to better understand and prevent the potential transmission of these zoonotic diseases from pigs to people in Vietnam. Conclusion Our study provides evidence to veterinarians and animal health professionals for evidence-based practice such as diagnosis, vaccination and zoonotic control. Further investigation into the possible role of different domestic animals, wildlife species or environmental factors is needed to identify the potential risk factors and transmission routes in Vietnam. 2019-08-01 2019-08-02T11:24:32Z 2019-08-02T11:24:32Z Journal Article https://hdl.handle.net/10568/102402 en Open Access Public Library of Science Hu Suk Lee, To Long Thanh, Nguyen Khanh Ly, Hung Nguyen-Viet, Thakur, K.K. and Grace, D. 2019. Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam. PLOS ONE 14(8): e0214701. |
| spellingShingle | zoonoses swine disease prevalence Hu Suk Lee To Long Thanh Nguyen Khanh Ly Hung Nguyen-Viet Thakur, Krishna K. Grace, Delia Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title | Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title_full | Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title_fullStr | Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title_full_unstemmed | Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title_short | Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam |
| title_sort | seroprevalence of leptospirosis and japanese encephalitis in swine in ten provinces of vietnam |
| topic | zoonoses swine disease prevalence |
| url | https://hdl.handle.net/10568/102402 |
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