Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing

To date, several viruses of different genera have been reported to infect yam (Dioscorea spp.). The full diversity of viruses infecting yam, however, remains to be explored. High-throughput sequencing (HTS) methods are increasingly being used in the discovery of new plant viral genomes. In this stud...

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Autores principales: Silva, G., Bömer, M., Rathnayake, A.I., Sewe, S.O., Visendi, P., Oyekanmi, J.O., Quain, M.D., Akomeah, B., Kumar, P. Lava, Seal, S.E.
Formato: Journal Article
Lenguaje:Inglés
Publicado: MDPI 2019
Materias:
Acceso en línea:https://hdl.handle.net/10568/101684
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author Silva, G.
Bömer, M.
Rathnayake, A.I.
Sewe, S.O.
Visendi, P.
Oyekanmi, J.O.
Quain, M.D.
Akomeah, B.
Kumar, P. Lava
Seal, S.E.
author_browse Akomeah, B.
Bömer, M.
Kumar, P. Lava
Oyekanmi, J.O.
Quain, M.D.
Rathnayake, A.I.
Seal, S.E.
Sewe, S.O.
Silva, G.
Visendi, P.
author_facet Silva, G.
Bömer, M.
Rathnayake, A.I.
Sewe, S.O.
Visendi, P.
Oyekanmi, J.O.
Quain, M.D.
Akomeah, B.
Kumar, P. Lava
Seal, S.E.
author_sort Silva, G.
collection Repository of Agricultural Research Outputs (CGSpace)
description To date, several viruses of different genera have been reported to infect yam (Dioscorea spp.). The full diversity of viruses infecting yam, however, remains to be explored. High-throughput sequencing (HTS) methods are increasingly being used in the discovery of new plant viral genomes. In this study, we employed HTS on yam to determine whether any undiscovered viruses were present that would restrict the international distribution of yam germplasm. We discovered a new virus sequence present in 31 yam samples tested and have tentatively named this virus “yam virus Y” (YVY). Twenty-three of the samples in which YVY was detected showed mosaic and chlorotic leaf symptoms, but Yam mosaic virus was also detected in these samples. Complete genome sequences of two YVY viral isolates were assembled and found to contain five open reading frames (ORFs). ORF1 encodes a large replication-associated protein, ORF2, ORF3 and ORF4 constitute the putative triple gene block proteins, and ORF5 encodes a putative coat protein. Considering the species demarcation criteria of the family Betaflexiviridae, YVY should be considered as a novel virus species in the family Betaflexiviridae. Further work is needed to understand the association of this new virus with any symptoms and yield loss and its implication on virus-free seed yam production.
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spelling CGSpace1016842025-11-11T10:42:19Z Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing Silva, G. Bömer, M. Rathnayake, A.I. Sewe, S.O. Visendi, P. Oyekanmi, J.O. Quain, M.D. Akomeah, B. Kumar, P. Lava Seal, S.E. rna betaflexiviridae yams viruses nigeria ghana genomes molecular markers To date, several viruses of different genera have been reported to infect yam (Dioscorea spp.). The full diversity of viruses infecting yam, however, remains to be explored. High-throughput sequencing (HTS) methods are increasingly being used in the discovery of new plant viral genomes. In this study, we employed HTS on yam to determine whether any undiscovered viruses were present that would restrict the international distribution of yam germplasm. We discovered a new virus sequence present in 31 yam samples tested and have tentatively named this virus “yam virus Y” (YVY). Twenty-three of the samples in which YVY was detected showed mosaic and chlorotic leaf symptoms, but Yam mosaic virus was also detected in these samples. Complete genome sequences of two YVY viral isolates were assembled and found to contain five open reading frames (ORFs). ORF1 encodes a large replication-associated protein, ORF2, ORF3 and ORF4 constitute the putative triple gene block proteins, and ORF5 encodes a putative coat protein. Considering the species demarcation criteria of the family Betaflexiviridae, YVY should be considered as a novel virus species in the family Betaflexiviridae. Further work is needed to understand the association of this new virus with any symptoms and yield loss and its implication on virus-free seed yam production. 2019-06 2019-06-25T12:45:36Z 2019-06-25T12:45:36Z Journal Article https://hdl.handle.net/10568/101684 en Open Access application/pdf MDPI Silva, G., Bömer, M., Rathnayake, A.I., Sewe, S.O., Visendi, P., Oyekanmi, J. O., ... & Seal, S.E. (2019). Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing. Plants, 8(6), 167-176.
spellingShingle rna
betaflexiviridae
yams
viruses
nigeria
ghana
genomes
molecular markers
Silva, G.
Bömer, M.
Rathnayake, A.I.
Sewe, S.O.
Visendi, P.
Oyekanmi, J.O.
Quain, M.D.
Akomeah, B.
Kumar, P. Lava
Seal, S.E.
Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title_full Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title_fullStr Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title_full_unstemmed Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title_short Molecular characterization of a new virus species identified in yam (Dioscorea spp.) by high-throughput sequencing
title_sort molecular characterization of a new virus species identified in yam dioscorea spp by high throughput sequencing
topic rna
betaflexiviridae
yams
viruses
nigeria
ghana
genomes
molecular markers
url https://hdl.handle.net/10568/101684
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