Resultados de búsqueda - Drugs evaluation.

Antibiotic quality and use practices amongst dairy farmers and drug retailers in central Kenyan highlands por Muloi, Dishon, Kurui, P., Sharma, Garima, Ochieng, Linnet, Ng'ang'a, Fredrick M., Gudda, Fredrick, Muthini, J.M., Grace, Delia, Dione, Michel M., Moodley, Arshnee, Muneri, C.

“…Data were collected from 248 dairy farms and 72 veterinary drug stores between February 2020 and October 2021. …”
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Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali por Mungube, E.O., Vitouley, H.S., Cudjoe, E.A., Diall, O., Boucoum, Z., Diarra, B., Sanogo, Y., Randolph, Thomas F., Bauer, B., Zessin, K.H., Clausen, Peter-Henning

“…Both a cross-sectional and a longitudinal study were carried out from November to December 2007 to evaluate trypanosomosis risk and susceptibility of trypanosomes to trypanocidal drug treatment in village cattle populations in south-east Mali. …”
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Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle por Diarra, B., Diall, O., Geerts, S., Kageruka, P., Lemmouchi, Y., Schacht, E., Eisler, M.C., Holmes, P.

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A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice por Geerts, S., Ndung'u, J.M., Murilla, G., Mbwambo, H., Sinyangwe, L., Machila, N., Delespaux, V., Brandt, J., Peregrine, A.S., McDermott, John J., Holmes, P.H., Eisler, M.C.

“…A simplified protocol for trypanocidal drug-sensitivity testing using just 3 doses for either isometamidium (0.1, 1.0 and 10 mg1kg b.w.) or diminazene (1, 20 and 40 mg/kg b.w.) was evaluated. …”
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Influence of the cattle body weight estimation for drug dosing on the pharmacokinetic and efficacy of ivermectin against Rhipicephalus (Boophilus) microplus por Miró, Maria Victoria, Sarli, Macarena, Rossner, Maria Victoria, Gomez, Viviana Daniela, Toffaletti, Jose Rodolfo, Lifschitz, Adrian Luis, Nava, Santiago

“…This study aimed to evaluate how the method of body weight estimation of a herd (average vs individual) for drug dosing may affect the pharmacokinetics and therapeutic efficacy of ivermectin 3.15% against Rhipicephalus (Boophilus) microplus. …”
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Fluazuron efficacy against Rhipicephalus microplus (Acari: Ixodidae) in cattle: Systemic exposure and pattern of tick drug uptake por Sarli, Macarena, Rossner, Maria Victoria, Miró, María Victoria, Lanusse, Carlos Edmundo, Segovia Stefani, Lautaro Ezequiel, Cabaña, Norma Elía, Nava, Santiago, Lifschitz, Adrian Luis

“…The aims of this work were to evaluate the relevance of the tick attachment site on the host’s body in the fluazuron (FZN) uptake by ticks through direct contact, characterizing the early distribution of the drug through the skin and adipose tissue of different anatomical regions. …”
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A community education intervention to improve bovine trypanosomiasis knowledge and appropriate use of trypanocidal drugs on smallholder farms in Kenya por Machila, N., Emongor, Rosemary, Shaw, A.P.M., Welburn, S.C., McDermott, John J., Maudlin, I., Eisler, M.C.

“…This paper describes the development, design, dissemination and evaluation of a communication intervention designed to promote appropriate usage of trypanocidal drugs in trypanosomiasis endemic areas of western and coastal Kenya. …”
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Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design por Lu, Stephen, Ascencio, Mariano, Torquato, Ricardo J.S., Florin-Christensen, Mónica, Tanaka, Aparecida S.

“…Moreover, rBbCp substrate specificity evaluation using a peptide phage display library showed a preference for Val > Leu > Phe. …”
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Training farmers in rational drug-use improves their management of cattle trypanosomosis: a cluster-randomised trial in south Mali por Grace, Delia, Randolph, Thomas F., Diall, O., Clausen, Peter-Henning

“…We carried out a stratified, cluster-randomised, controlled trial in south Mali in 2004 to evaluate the impact of providing information on the diagnosis and treatment of bovine trypanosomosis by farmers. …”
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Pharmacological and epidemiological studies on the drug-sensitivity of trypanosomes isolated from a peri-urban dairy production system in Uganda. por Olila, D.

“…It had the following main objectives: a) to characterise the drug-sensitivity phenotype(s) of trypanosome field isolates collected between 1995 and 1996 from cattle; b) to determine the species and subspecies of trypanosome populations and their prevalence over the same period in cattle; c) to evaluate an isometamidium-enzyme-linked immunosorbent assay (ISMM-ELISA) using sera and use the resulting data to monitor the use of isometamidium and as a tool to indirectly assay for drug resistance; d) to establish whether the trypanosome isolates from cattle might be of zoonotic importance; and e) to analyse the factors associated with trypanocide usage and efficacy. …”
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Trypanocidal drug resistance in four regions of Cote d'Ivoire: Importance and possible impact on sustainability of integrated strategies for trypanosomiasis control por D'Ieteren, G.D.M., Coulibaly, L., Atse, P.A., Hecker, P.A., Krebs, H.A., Rowlands, G.J., Leak, S.G.A., Nagda, S.M.

“…The efficacies of three trypanocidal drugs, diminazene aceturate, isometamidium chloride and homidium bromide, were evaluated in four representative areas of Cote d'Ivoire with different production systems, degree of integration of different trypanosomosis control approaches and delivery of veterinary inputs. …”
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In vitro comparison of acyclovir, ganciclovir and cidofovir against equid alphaherpesvirus 3 and evaluation of their efficacy against six field isolates = Comparación in vitro de a... por Vissani, Maria Aldana, Zabal, Osvaldo Alfredo, Tordoya, Maria Silvia, Parreño, Viviana, Thiry, Etienne, Barrandeguy, Maria Edith

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Anthelmintic effect of Halothamus somalensis in Arsi-Bale goats por Dawo, F., Tibbo, Markos

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African animal trypanosomosis in West Africa: What makes livestock keepers not use other means of control in a drug resistance context? por Affognon, Hippolyte D., Randolph, Thomas F.

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Disseminating research results on trypanocide resistance in West Africa: a method for identifying effective pathways por Affognon, Hippolyte D., Matsaert, H., Puskur, Ranjitha, Randolph, Thomas F.

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Chemotherapy and electrotherapy significantly fast tracks virus elimination in sweetpotato por Gatimu, R., Ogero, K.

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The antiplasmodial activity of spermine alkaloids isolated from Albizia gummifera por Rukunga, G.M., Muregi, F.W., Tolo, F.M., Omar, S.A., Mwitari, P., Muthaura, C.N., Omlin, F., Lwande, W., Hassanali, A., Githure, J., Iraqi, F.W., Mungai, G.M., Kraus, W., Kofi-Tsekpo, W.M.

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Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycopr... por Lloberas, María Mercedes, Alvarez, Luis Ignacio, Entrocasso, Carlos, Virkel, Guillermo Leon, Ballent, Mariana, Maté, María Laura, Lanusse, Carlos Edmundo, Lifschitz, Adrian Luis

“…This comparative pharmacological evaluation of three of the most used macrocyclic lactones compounds provides new insights into the action of these drugs.…”
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Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products : potential pH-dependent inhibition explored through computer-aided drug design por Goyzueta-Mamani, Luis Daniel, Barazorda-Ccahuana, Haruna Luz, Candia-Puma, Mayron Antonio, Galdino, Alexsandro Sobreira, Machado-de-Avila, Ricardo Andrez, Giunchetti, Rodolfo Cordeiro, Medina-Franco, José L., Florin-Christensen, Mónica, Ferraz Coelho, Eduardo Antonio, Chavez Fumagalli, Miguel Angel

“…Using computer-aided drug design (CADD) approaches, the potential inhibitory effect of these NP candidates was evaluated by inhibiting the Mannosyl-oligosaccharide Glucosidase Protein (MOGS) from Leishmania infantum, an enzyme essential for the protein glycosylation process, at various pH to mimic the parasite’s changing environment. …”
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Importance of traditional protected areas for the collection of medicinal plants, Kongo-Central (DRC) por Flavien, N.B., Vanhove, W., Termote, Céline, Damme, Patrick van

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