Resultados de búsqueda - Computer-aided design.
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Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products : potential pH-dependent inhibition explored through computer-aided drug design
Publicado 2024“…For this reason, based on previous research, we screened natural products (NP) from Nuclei of Bioassays, Ecophysiology, and Biosynthesis of Natural Products Database (NuBBEDB), Mexican Compound Database of Natural Products (BIOFACQUIM), and Peruvian Natural Products Database (PeruNPDB) databases, in addition to structural analogs of Miglitol and Acarbose, which have been suggested as treatments for VL and have shown encouraging action against parasite’s N-glycan biosynthesis. Using computer-aided drug design (CADD) approaches, the potential inhibitory effect of these NP candidates was evaluated by inhibiting the Mannosyl-oligosaccharide Glucosidase Protein (MOGS) from Leishmania infantum, an enzyme essential for the protein glycosylation process, at various pH to mimic the parasite’s changing environment. …”
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Artículo -
Valuation of 2-wheel tractors for Life Cycle Assessment analysis : technical report
Publicado 2023“…The present report describes the progress of this collaboration including the 2-wheel tractor disassembly to analyze and cost the complete manufacturing process (methods, materials, and resources). For this, computer-aided design (CAD) software SolidWorks© was used for creating accurate 3D models of each piece of the tractor, facilitating a detailed visualization of the geometry and operations required for construction. …”
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Informe técnico -
BioMoby extensions to the Taverna workflow management and enactment software
Publicado 2006“…Here we describe the marriage of these two projects in the form of a Taverna plug-in that provides access to many of BioMoby's features through the Taverna interface.The exposed BioMoby functionality aids in the design of "sensible" BioMoby workflows, aids in pipelining BioMoby and non-BioMoby-based resources, and ensures that end-users need only a minimal understanding of both BioMoby, and the Taverna interface itself. …”
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Journal Article -
Linking the economics of water, energy, and food: A nexus modeling approach
Publicado 2017Enlace del recurso
Artículo preliminar -
Pre-treatment of soil X-ray powder diffraction data for cluster analysis
Publicado 2019“…The efforts required for conventional approaches of soil XRPD data analysis are currently restrictive for such large data sets, resulting in a need for computational methods that can aid in defining soil property – soil mineralogy relationships. …”
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Construction of a generalised farm typology to aid selection, targeting and scaling of onfarm research
Publicado 2023Enlace del recurso
Journal Article -
Advancing multivariate time series similarity assessment: an integrated computational approach
Publicado 2025“…MTASA is built upon a hybrid methodology designed to optimise time series alignment, complemented by a multiprocessing engine that enhances the utilisation of computational resources. …”
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Journal Article -
Vigilancia científica sobre desarrollo de vacunas contra Leptospira spp.
Publicado 2025Enlace del recurso
Estudio de vigilancia -
Proofing direct-seeded rice with better root plasticity and architecture
Publicado 2021Enlace del recurso
Journal Article