Search Results - Drugs Testing.

In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants by Geerts, S., Ndung'u, J.M., Murilla, G., Mbwambo, H., Sirryangwe, L., Machila, N., Delespaux, V., Brandt, J., Peregrine, A.S., McDermott, John J., Holmes, P.H., Eisler, M.C.

“…Besides the in vitro test, two tests are very commonly used for the detection of trypanocidal drug resistance: the tests in mice and in ruminants. …”
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A drug incubation infectivity test (DIIT) for assessing resistance to trypanosomes by Kaminsky, R., Gumm, I.D., Chuma, Francis, Zweygarth, E.

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Trypanocidal drug screening on Trypanosoma (Dutonella) vivax in vitro by Waithaka, H.K., Borowy, N.K., Gettinby, George, Scott, J., Hirumi, H.

Subjects: “…drug therapy…”
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Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test by Knoppe, T.N., Bauer, B., McDermott, John J., Peregrine, A.S., Mehlitz, D., Clausen, Peter-Henning

“…Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kenedougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubation infectivity test (DIIT). …”
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Evaluation of a field test for trypanotolerance in young N'Dama cattle by Trail, J.C.M., D'Ieteren, G.D.M., Colardelle, C., Maille, J.C., Ordner, G., Sauveroche, B., Yangari, G.

“…Evaluates components of a short term test for trypanotolerance criteria in N'Dama post-weaners exposed to a medium natural trypanosome challenge in Gabon; compares the effectiveness of different measures of control of development of anaemia; and measures the post-test recovery of packed red cell volume (PCV) values following treatment with a trypanocidal drug.…”
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Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle by Eisler, M.C., Brandt, J., Bauer, B., Clausen, Peter-Henning, Delespaux, V., Holmes, P.H., Ilemobade, A., Machila, N., Mbwambo, H., McDermott, John J., Mehlitz, D., Murilla, G., Ndung'u, J.M., Peregrine, A.S., Sidibe, I., Sinyangwe, L., Geerts, S.

“…The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack of standardisation and hence it may be difficult to compare the results of different investigators. …”
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A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice by Geerts, S., Ndung'u, J.M., Murilla, G., Mbwambo, H., Sinyangwe, L., Machila, N., Delespaux, V., Brandt, J., Peregrine, A.S., McDermott, John J., Holmes, P.H., Eisler, M.C.

“…This method requires at least 15 mice per drug and represents a significant reduction over full CD50 testing. …”
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Detecting resistance of trypanosomal infection to diminazene aceturate - a possible field test? by Rowlands, G.J.

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Suratex: A simple latex agglutination antigen test for diagnosis of Trypanosoma evansi infection (Surra) by Nantulya, V.M.

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Evaluation of a short-term in vitro growth-inhibition test to determine susceptibility of Trypanosoma vivax stocks to various trypanocides by Zweygarth, E., Kaminsky, R., Moloo, S.K.

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Trypanocidal drug resistance in eastern province of Zambia by Sinyangwe, L., Delespaux, V., Brandt, J., Geerts, S., Mubanga, J., Machila, N., Holmes, P.H., Eisler, M.C.

“…The remainder was caused by Trypanosoma vivax (2%) and Trypanosoma brucei (2%). Tests in mice showed that of the stabilates collected, 24 (34%) were resistant to only isometamidium chloride, 8 (11.3%) were resistant to only diminazene aceturate, 1 (1.4%) was resistant to both drugs, and 38 (53.5%) were sensitive to both drugs. …”
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Prueba de eficacia de fármacos antihelmínticos en una majada de ovinos del sur santafecino = Efficacy test of anthelmintic drugs in a sheep flock in southern Santa Fe by Morlacco, María Belén, Aguzzi, Yanina, Bichara, J., Morici, Gabriel Edgardo, Bruttomesso, Mía Florencia, Schapiro, Javier Hernan

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Drug combination of ciprofloxacin and polymyxin B for the treatment of multidrug-resistant Acinetobacter baumannii infections: A drug pair limiting the development of resistance by Wang, J., Stegger, M., Moodley, Arshnee, Yang, M.

“…This study suggests that inhalable spray–dried powders composed of the combination of CIP and PMB is promising for the treatment of respiratory infections caused by A. baumannii, and this combination can enhance the killing efficiency and suppress the development of drug resistance.…”
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Studies on in Vitrro assessment of "drug resistance" in trypanosoma vivax. by Kitosi, D.S.

“…It was evaluated whether in vitro tests had the potential to distinguish between drug-sensitive and drug-resistant stocks of T vivax. …”
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Methods for detection of drug resistance in trypanosomes - new developments? by Peregrine, A.S., Wells, C.W., Wilkes, J.M.

“…Characterising the drug susceptibility of trypanosomes that are pathogenic for domestic livestock has for many years been carried out either in vivo, using large or small animals, or by using various in vitro cultivation methodologies (Peregrine, 1994). …”
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Evidence of improper usage of veterinary drugs in cattle in Maasailand, Kenya by Irungu, P., Bett, Bernard K., Mbogoh, S.G., Nyamwaro, Sospeter S., Murilla, G.A., Randolph, Thomas F.

“…One hundred and thirteen farmers in Kajiado and Narok districts were interviewed between October 2005 and February 2006 using a pre-tested questionnaire. The aim was to gather information on farmers’ veterinary drug use practices at the farm level. …”
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Anthelmintic resistance in livestock in Africa: review of the current status by Gatitu, Lucy, Kasudi, Mitchelle R., Githigia, S., Moodley, Arshnee, Muloi, Dishon M.

“…Equally important is the development of sustainable parasite control strategies and the promotion of responsible anthelmintic use to preserve the efficacy of existing drugs.…”
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Development of a colorimetric assay to assess drug susceptibilities in trypanosoma congolense. by Wasike, R.P.N.

“…The optical density measured at 540 nm was found to increase in direct proportion to the number oftrypanosomes in the range of 5.0xl04 to 8.0x105 organisms 200 sample, The modified assay was tested using seven antitrypanosomal drugs on two stocks and five clones of T. congolense. …”
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Best-bet integrated strategies for containing drug-resistant trypanosomes in cattle by Mungube, E.O., Diall, O., Baumann, M.P.O., Hoppenheit, A., Hinney, B., Bauer, B., Sanogo, Y., Maiga, B., Zessin, K.H., Randolph, Thomas F., Clausen, Peter-Henning

“…Trypanosomosis is mainly controlled using trypanocidal drugs, but the effective use of drugs is threatened by the development of widespread resistance. …”
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Multi-drug resistant Staphylococcus aureus carriage in abattoir workers in Busia, Kenya by Obanda, B.A., Gibbons, C.L., Fèvre, Eric M., Bebora, L., Gitao, G., Ogara, W., Wang, S.-H., Gebreyes, W., Ngetich, R., Blane, B., Coll, F., Harrison, E.M., Kariuki, S., Peacock, S.J., Cook, Elizabeth A.J.

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