Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial.

Bibliographic Details
Title: Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Authors: Watanabe J; Department of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan., Muro K; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan., Shitara K; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.; Department of Immunology, Nagoya University Graduate School of Medicine, Aichi, Japan., Yamazaki K; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Shiozawa M; Division of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan., Ohori H; Division of Medical Oncology, Japanese Red Cross Ishinomaki Hospital, Miyagi, Japan., Takashima A; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan., Yokota M; Department of General Surgery, Kurashiki Central Hospital, Okayama, Japan., Makiyama A; Department of Hematology/Oncology, Japan Community Healthcare Organization, Fukuoka, Japan., Akazawa N; Department of Gastrointestinal Surgery, Sendai City Medical Center, Sendai Open Hospital, Miyagi, Japan., Ojima H; Department of Gastroenterological Surgery, Gunma Prefectural Cancer Center, Gunma, Japan., Yuasa Y; Department of Gastroenterological Surgery, Japanese Red Cross Tokushima Hospital, Tokushima, Japan., Miwa K; Department of Cancer Multimodel Therapy Center, Kurume University Hospital, Fukuoka, Japan., Yasui H; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Oki E; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Sato T; Research and Development Center for Medical Education, Department of Clinical Skills Education, Kitasato University School of Medicine, Sagamihara, Japan., Naitoh T; Department of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Japan., Komatsu Y; Division of Cancer Chemotherapy, Hokkaido University Hospital Cancer Center, Sapporo, Japan., Kato T; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan., Hihara M; Japan Medical Affairs, Japan Oncology Business Unit, Takeda Pharmaceutical Company Ltd, Tokyo, Japan., Soeda J; Japan Medical Affairs, Japan Oncology Business Unit, Takeda Pharmaceutical Company Ltd, Tokyo, Japan., Misumi T; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan., Yamamoto K; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan., Akagi K; Division of Molecular Diagnosis and Cancer Prevention, Saitama Cancer Center, Saitama, Japan., Ochiai A; Pathology Division, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.; now with the Research Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, Japan., Uetake H; National Hospital Organization, Disaster Medical Center, Tokyo, Japan., Tsuchihara K; Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan., Yoshino T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Source: JAMA [JAMA] 2023 Apr 18; Vol. 329 (15), pp. 1271-1282.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Complete
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Description
ISSN:1538-3598
DOI:10.1001/jama.2023.4428