Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated with an arrested cell cycle in G1/G0 phase.

Bibliographic Details
Title:	Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated with an arrested cell cycle in G1/G0 phase.
Authors:	Avello V; Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.; Centro de Biotecnología, Universidad Técnica Federico Santa María, Valparaíso, Chile., Torres M; Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.; Department of Chemical Engineering, Biochemical and Bioprocess Engineering Group, University of Manchester, Manchester, United Kingdom., Vergara M; Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile., Berrios J; Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile., Valdez-Cruz NA; Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México., Acevedo C; Centro de Biotecnología, Universidad Técnica Federico Santa María, Valparaíso, Chile.; Centro Científico Tecnológico de Valparaíso CCTVaL, Universidad Técnica Federico Santa María, Valparaíso, Chile.; Departamento de Física, Universidad Técnica Federico Santa María, Valparaíso, Chile., Molina Sampayo M; Centro de InmunoBiotecnología, Universidad de Chile, Santiago, Chile., Dickson AJ; Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.; Department of Chemical Engineering, Biochemical and Bioprocess Engineering Group, University of Manchester, Manchester, United Kingdom., Altamirano C; Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.; Centro Regional de Estudio en Alimentos Saludables, R17A10001, Valparaíso, Chile.
Source:	PloS one [PLoS One] 2022 Nov 14; Vol. 17 (11), pp. e0277620. Date of Electronic Publication: 2022 Nov 14 (Print Publication: 2022).
Publication Type:	Journal Article; Research Support, Non-U.S. Gov't
Journal Info:	Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database:	MEDLINE Complete
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ISSN:	1932-6203
DOI:	10.1371/journal.pone.0277620