[Ultrasonographic measurement of cervical length in twin pregnancies with preterm labor: comparison with singleton pregnancies].
|Title:||[Ultrasonographic measurement of cervical length in twin pregnancies with preterm labor: comparison with singleton pregnancies].|
|Transliterated Title:||Mesure échographique de la longueur du col de l'utérus dans les grossesses gémellaires avec menace d'accouchement prématuré: comparaison avec les grossesses uniques.|
|Authors:||Gonzalez N; Service de gynécologie-obstétrique, institut mère-enfant Alix-de-Champagne, hôpital Maison-Blanche, 45, rue Cognacq-Jay, 51092 Reims cedex, France., Bige V, Kandoussi S, Graesslin O, Quereux C, Gabriel R|
|Source:||Gynecologie, obstetrique & fertilite [Gynecol Obstet Fertil] 2004 Feb; Vol. 32 (2), pp. 122-7.|
|Publication Type:||Comparative Study; Journal Article|
|Journal Info:||Publisher: Elsevier Country of Publication: France NLM ID: 100936305 Publication Model: Print Cited Medium: Print ISSN: 1297-9589 (Print) Linking ISSN: 12979589 NLM ISO Abbreviation: Gynecol Obstet Fertil Subsets: MEDLINE|
|Imprint Name(s):||Original Publication: Paris : Elsevier, c2000-|
|MeSH Terms:||Obstetric Labor, Premature* , Pregnancy, Multiple* , Ultrasonography, Prenatal*, Cervix Uteri/*diagnostic imaging, Adult ; Delivery, Obstetric ; Female ; Fibronectins/analysis ; Forecasting ; Humans ; Predictive Value of Tests ; Pregnancy ; Prospective Studies ; Sensitivity and Specificity ; Twins ; Vagina/chemistry|
|Abstract:||Objective: Our purpose was to assess the utility of ultrasonographic measurement of cervical length for predicting preterm delivery in pregnant women with twin pregnancy and preterm labor.
Patients and Method: Prospective study in 192 singleton and 66 twin pregnancies with preterm labor before 34 weeks. Vaginal sonography for measurement of cervical length, and screening for fetal fibronectin in vaginal smears were performed at admission. The incidence of delivery before 34 weeks was compared with cervical length and the presence of fetal fibronectin.
Results: In singleton pregnancies, delivery before 34 weeks was significantly more frequent in women with a cervical length <30 mm (26.6 vs. 2.0%; P = 0.0004), or presence of fetal fibronectin (27.5 vs. 6.0%; P = 0.001). The corresponding negative predictive values (NPV) were 98% and 94%, respectively. In twin pregnancies, receiver characteristic curve analysis showed that a cervical length of 20 mm had the highest diagnostic performance in predicting preterm delivery. The corresponding NPV was 63%. In this group, delivery before 34 weeks showed no significant difference in women with a cervical length < 30 mm (43.7 vs. 38.8%), cervical length < 20 mm (52.0 vs. 36.6%, P = 0.219), or presence of fetal fibronectin (47.6 vs. 21.7%, P = 0.0705).
Discussion and Conclusion: Ultrasonographic measurement of cervical length does not predict preterm delivery in twin pregnancies with preterm labor.
|Substance Nomenclature:||0 (Fibronectins)|
|Entry Date(s):||Date Created: 20040505 Date Completed: 20040805 Latest Revision: 20161124|