Authors: Sabouri, Z., Schofield, P., Horikawa, K., Spierings, E., Kipling, D., Randall, K. L., Langley, D., Roome, B., Vazquez-Lombardi, R., Rouet, R., Hermes, J., Chan, T. D., Brink, R., Dunn-Walters, D. K., Christ, D., Goodnow, C. C.
Subject Terms: R1, PNAS Plus, Multidisciplinary, Somatic hypermutation, Affinity maturation, Avidity, Immunology, Germinal center, Biology, Immunoglobulin M, biology.protein, Antigen, Immunoglobulin D, Epitope, Molecular biology
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Authors: Vazquez-Lombardi R; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland; Engimmune Therapeutics AG, Hegenheimermattweg 167A, 4123 Allschwil, Switzerland. Electronic address: rodrigo.vl@engimmune.com., Jung JS; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Schlatter FS; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Mei A; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Mantuano NR; Department of Biomedicine, Universitätsspital Basel, Basel, Switzerland., Bieberich F; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Hong KL; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Kucharczyk J; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Kapetanovic E; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Aznauryan E; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Weber CR; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland., Zippelius A; Department of Biomedicine, Universitätsspital Basel, Basel, Switzerland., Läubli H; Department of Biomedicine, Universitätsspital Basel, Basel, Switzerland., Reddy ST; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland. Electronic address: sai.reddy@ethz.ch.
Source: Immunity [Immunity] 2022 Oct 11; Vol. 55 (10), pp. 1953-1966.e10. Date of Electronic Publication: 2022 Sep 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
MeSH Terms: Immunotherapy, Adoptive* , Receptors, Antigen, T-Cell*, Antigens, Neoplasm ; Humans ; Immunotherapy ; Peptides
Authors: Ehling RA; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Weber CR; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; deepCDR Biologics AG, Basel, Switzerland., Mason DM; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; deepCDR Biologics AG, Basel, Switzerland., Friedensohn S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; deepCDR Biologics AG, Basel, Switzerland., Wagner B; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Bieberich F; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Kapetanovic E; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Vazquez-Lombardi R; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Di Roberto RB; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Hong KL; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; Botnar Research Centre for Child Health, Basel, Switzerland., Wagner C; deepCDR Biologics AG, Basel, Switzerland., Pataia M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; deepCDR Biologics AG, Basel, Switzerland., Overath MD; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Sheward DJ; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Murrell B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Yermanos A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; Botnar Research Centre for Child Health, Basel, Switzerland; Institute of Microbiology and Immunology, Department of Biology, ETH Zurich, Zurich, Switzerland; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Cuny AP; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; Swiss Institute of Bioinformatics, Mattenstr. 26, 4058 Basel, Switzerland., Savic M; Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland; Department of Surgery, Oral and Cranio-Maxillofacial Surgery, University Hospital Basel, Basel, Switzerland; Department of Health, Economics and Health Directorate, Canton Basel-Landschaft, Switzerland., Rudolf F; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; Swiss Institute of Bioinformatics, Mattenstr. 26, 4058 Basel, Switzerland., Reddy ST; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland; Botnar Research Centre for Child Health, Basel, Switzerland. Electronic address: sai.reddy@ethz.ch.
Source: Cell reports [Cell Rep] 2022 Jan 18; Vol. 38 (3), pp. 110242. Date of Electronic Publication: 2021 Dec 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
MeSH Terms: Antibodies, Neutralizing/*isolation & purification , Plasma Cells/*metabolism , SARS-CoV-2/*immunology , Single-Cell Analysis/*methods, Animals ; Antibodies, Viral/isolation & purification ; COVID-19/immunology ; COVID-19/prevention & control ; Cells, Cultured ; Cohort Studies ; Gene Library ; HEK293 Cells ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Mammals ; Neutralization Tests ; Peptide Library ; Plasma Cells/chemistry
Accede al texto completo Authors: Bieberich F; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Vazquez-Lombardi R; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Yermanos A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; Institute of Microbiology and Immunology, Department of Biology, ETH Zurich, Zurich, Switzerland.; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Botnar Research Centre for Child Health, Basel, Switzerland., Ehling RA; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Mason DM; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; deepCDR Biologics AG, Basel, Switzerland., Wagner B; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Kapetanovic E; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Di Roberto RB; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Weber CR; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; deepCDR Biologics AG, Basel, Switzerland., Savic M; Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland.; Department of Surgery, Oral and Cranio-Maxillofacial Surgery, University Hospital Basel, Basel, Switzerland.; Department of Health, Economics and Health Directorate, Canton Basel-Landschaft, Switzerland., Rudolf F; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Reddy ST; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; Botnar Research Centre for Child Health, Basel, Switzerland.
Source: Frontiers in immunology [Front Immunol] 2021 Jul 12; Vol. 12, pp. 701085. Date of Electronic Publication: 2021 Jul 12 (Print Publication: 2021).
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
MeSH Terms: Aging/*immunology , B-Lymphocytes/*immunology , CD4-Positive T-Lymphocytes/*immunology , CD8-Positive T-Lymphocytes/*immunology , COVID-19/*immunology , SARS-CoV-2/*physiology, Adaptive Immunity ; Adult ; Aged ; Cells, Cultured ; Convalescence ; Female ; Humans ; Male ; Middle Aged ; Receptors, Antigen, B-Cell/genetics ; Receptors, Antigen, T-Cell/genetics ; Single-Cell Analysis ; Transcriptome ; Young Adult
Authors: Yermanos A; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Agrafiotis A; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Kuhn R; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Robbiani D; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Yates J; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Papadopoulou C; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Han J; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Sandu I; Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland., Weber C; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Bieberich F; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Vazquez-Lombardi R; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Dounas A; Institute for Biomedical Engineering, University and ETH Zurich, 8092 Zurich, Switzerland., Neumeier D; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Oxenius A; Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland., Reddy ST; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.
Source: NAR genomics and bioinformatics [NAR Genom Bioinform] 2021 Apr 14; Vol. 3 (2), pp. lqab023. Date of Electronic Publication: 2021 Apr 14 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101756213 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-9268 (Electronic) Linking ISSN: 26319268 NLM ISO Abbreviation: NAR Genom Bioinform Subsets: PubMed not MEDLINE
Authors: Di Roberto RB; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Castellanos-Rueda R; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Frey S; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Egli D; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Vazquez-Lombardi R; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Kapetanovic E; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Kucharczyk J; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Reddy ST; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland. Electronic address: sai.reddy@ethz.ch.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Dec 02; Vol. 28 (12), pp. 2564-2576. Date of Electronic Publication: 2020 Aug 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
MeSH Terms: Antigens, Neoplasm/*immunology , Breast Neoplasms/*immunology , Cell Engineering/*methods , Immunotherapy, Adoptive/*methods , Receptor, ErbB-2/*immunology , Receptors, Antigen, T-Cell, alpha-beta/*genetics , Receptors, Antigen, T-Cell, alpha-beta/*immunology , Receptors, Chimeric Antigen/*genetics , Receptors, Chimeric Antigen/*immunology, Animals ; Antibody Affinity ; Antigens, Neoplasm/metabolism ; Breast Neoplasms/pathology ; CRISPR-Cas Systems ; Coculture Techniques ; Female ; Gene Editing/methods ; HEK293 Cells ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Interleukin-2/genetics ; Interleukin-2/metabolism ; MCF-7 Cells ; Mice ; Receptor, ErbB-2/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Receptors, Chimeric Antigen/metabolism ; Single-Chain Antibodies/immunology
Authors: Vazquez-Lombardi R; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Loetsch C; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Zinkl D; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia., Jackson J; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia., Schofield P; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia., Deenick EK; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., King C; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Phan TG; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Webster KE; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Sprent J; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Christ D; Immunology Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia.
Source: Nature communications [Nat Commun] 2017 May 12; Vol. 8, pp. 15373. Date of Electronic Publication: 2017 May 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Authors: Porebski BT; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, CambridgeCB2 0QH, UK., Conroy PJ; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Drinkwater N; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Schofield P; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia.; Faculty of Medicine, St Vincent's Clinical School, The University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia., Vazquez-Lombardi R; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia.; Faculty of Medicine, St Vincent's Clinical School, The University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia., Hunter MR; Department of Pathology, University of Cambridge, CambridgeCB2 1QP, UK., Hoke DE; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Christ D; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia.; Faculty of Medicine, St Vincent's Clinical School, The University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia., McGowan S; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Buckle AM; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Source: Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2016 Nov 01; Vol. 29 (11), pp. 541-550.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101186484 Publication Model: Print Cited Medium: Internet ISSN: 1741-0134 (Electronic) Linking ISSN: 17410126 NLM ISO Abbreviation: Protein Eng Des Sel Subsets: PubMed not MEDLINE; MEDLINE
Authors: Schofield P; Garvan Institute of Medical Research, Sydney, NSW, Australia.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia., Vazquez-Lombardi R; Garvan Institute of Medical Research, Sydney, NSW, Australia., Abdelatti M; Garvan Institute of Medical Research, Sydney, NSW, Australia.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia., Nevoltris D; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Goodnow CC; Garvan Institute of Medical Research, Sydney, NSW, Australia.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia., Christ D; Garvan Institute of Medical Research, Sydney, NSW, Australia.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia., Reed JH; Garvan Institute of Medical Research, Sydney, NSW, Australia. j.reed@garvan.org.au.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia. j.reed@garvan.org.au.
Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1827, pp. 287-309.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE
MeSH Terms: Epitopes*, Antigens/*blood , B-Lymphocytes/*immunology , Chromatography, Affinity/*methods , Sequence Analysis, Protein/*methods, Electrophoresis, Polyacrylamide Gel ; Fluorescent Dyes/metabolism ; Humans ; Immunoglobulin Fab Fragments/metabolism ; Interferometry ; Receptors, Antigen, B-Cell/chemistry ; Receptors, Antigen, B-Cell/metabolism
Authors: Vazquez-Lombardi R; Garvan Institute of Medical Research, Sydney, NSW, Australia., Nevoltris D; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Rouet R; Garvan Institute of Medical Research, Sydney, NSW, Australia., Christ D; Garvan Institute of Medical Research, Sydney, NSW, Australia. d.christ@garvan.org.au.; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia. d.christ@garvan.org.au.
Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1827, pp. 313-334.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE
MeSH Terms: Antibodies, Monoclonal/*metabolism , Immunoglobulin G/*metabolism , Protein Engineering/*methods, Cell Line ; Chromatography, Affinity ; DNA/metabolism ; Genetic Vectors/metabolism ; Humans ; Immunoglobulin G/chemistry ; Immunoglobulin Variable Region/chemistry ; Plasmids/metabolism ; Protein Domains ; Recombinant Proteins/metabolism ; Transfection
Authors: Vazquez-Lombardi R; Garvan Institute of Medical Research, Sydney, Australia., Nevoltris D; Garvan Institute of Medical Research, Sydney, Australia., Luthra A; Garvan Institute of Medical Research, Sydney, Australia.; St Vincent' Clinical School, University of New South Wales, Sydney, Australia., Schofield P; Garvan Institute of Medical Research, Sydney, Australia.; St Vincent' Clinical School, University of New South Wales, Sydney, Australia., Zimmermann C; School of Business Administration, University of San Diego, San Diego, California, USA.; Rady School of Management, University of California San Diego, La Jolla, California, USA., Christ D; Garvan Institute of Medical Research, Sydney, Australia.; St Vincent' Clinical School, University of New South Wales, Sydney, Australia.
Source: Nature protocols [Nat Protoc] 2018 Jan; Vol. 13 (1), pp. 99-117. Date of Electronic Publication: 2017 Dec 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE
MeSH Terms: Antibodies/*genetics , Protein Engineering/*methods , Recombinant Proteins/*genetics , Recombinant Proteins/*isolation & purification, Animals ; Antibodies/metabolism ; Cells, Cultured ; Chromatography, Affinity ; Electrophoresis, Polyacrylamide Gel/methods ; Genetic Vectors ; Humans ; Immunoglobulin Fab Fragments/genetics ; Immunoglobulin Fab Fragments/isolation & purification ; Immunoglobulin Fab Fragments/metabolism ; Immunoglobulin G/genetics ; Immunoglobulin G/metabolism ; Interferometry/methods ; Mammals ; Recombinant Proteins/metabolism
Authors: Loetsch C; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Warren J; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia., Laskowski A; Murdoch Children's Research Institute, The Royal Children's Hospital, Flemington Rd., Parkville, VIC 3052, Australia., Vazquez-Lombardi R; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Jandl C; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Langley DB; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Christ D; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Thorburn DR; Murdoch Children's Research Institute, The Royal Children's Hospital, Flemington Rd., Parkville, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Parkville VIC 3010, Australia., Ryugo DK; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Sprent J; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., Batten M; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia., King C; Department of Immunology, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Department of Medicine, University of New South Wales, Sydney, NSW 2010, Australia. Electronic address: c.king@garvan.org.au.
Source: Cell reports [Cell Rep] 2017 Nov 07; Vol. 21 (6), pp. 1624-1638.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
MeSH Terms: Erythrocytes/*immunology , RNA/*immunology, Adaptor Proteins, Signal Transducing/chemistry ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Cytokines/blood ; Cytokines/metabolism ; DEAD Box Protein 58/metabolism ; Down-Regulation/drug effects ; Humans ; Immunity, Humoral/drug effects ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondrial Membrane Transport Proteins/metabolism ; Mitochondrial Precursor Protein Import Complex Proteins ; Poly I-C/pharmacology ; Sheep ; Signal Transduction ; Spleen/cytology ; Spleen/drug effects ; Spleen/metabolism ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Toll-Like Receptors/metabolism
Authors: Corpuz TM; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and., Vazquez-Lombardi R; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Luong JK; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and., Warren J; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and., Stolp J; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and., Christ D; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., King C; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Brink R; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Sprent J; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia., Webster KE; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and k.webster@garvan.org.au.; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2010, Australia.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Oct 01; Vol. 199 (7), pp. 2366-2376. Date of Electronic Publication: 2017 Aug 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
MeSH Terms: Interleukin-17/*biosynthesis , Interleukin-2/*immunology , Interleukin-2/*metabolism , Receptors, Antigen, T-Cell, gamma-delta/*immunology , T-Lymphocytes/*immunology, Animals ; Cell Differentiation ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cytokines/biosynthesis ; Flow Cytometry ; Inflammation ; Interferon-gamma/biosynthesis ; Interferon-gamma/immunology ; Interleukin-17/immunology ; Interleukin-2/deficiency ; Interleukin-2/genetics ; Interleukin-23/metabolism ; Mice ; Mice, Inbred C57BL ; Positive Regulatory Domain I-Binding Factor 1 ; Receptors, Interleukin-7/genetics ; Signal Transduction ; T-Lymphocytes/drug effects ; T-Lymphocytes/physiology ; Transcription Factors/genetics ; Transcription Factors/metabolism
Authors: Vazquez-Lombardi R; Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia; The University of New South Wales, Faculty of Medicine, St Vincent's Clinical School, Darlinghurst, Sydney, NSW 2010, Australia., Phan TG; Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia; The University of New South Wales, Faculty of Medicine, St Vincent's Clinical School, Darlinghurst, Sydney, NSW 2010, Australia., Zimmermann C; University of San Diego, School of Business Administration, 5998 Alcala Park, San Diego, CA 92110, USA., Lowe D; MedImmune Ltd., Granta Park, Cambridge CB21 6GH, UK., Jermutus L; MedImmune Ltd., Granta Park, Cambridge CB21 6GH, UK; Trinity Hall, University of Cambridge, Trinity Lane CB2 1TJ, UK. Electronic address: jermutusl@medimmune.com., Christ D; Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia; The University of New South Wales, Faculty of Medicine, St Vincent's Clinical School, Darlinghurst, Sydney, NSW 2010, Australia. Electronic address: d.christ@garvan.org.au.
Source: Drug discovery today [Drug Discov Today] 2015 Oct; Vol. 20 (10), pp. 1271-83. Date of Electronic Publication: 2015 Sep 07.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5832 (Electronic) Linking ISSN: 13596446 NLM ISO Abbreviation: Drug Discov Today Subsets: MEDLINE
MeSH Terms: Drug Delivery Systems* , Drug Design*, Proteins/*administration & dosage, Animals ; Humans ; Proteins/pharmacology
Authors: Sabouri Z; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;, Schofield P; Immunology Division, Garvan Institute of Medical Research and., Horikawa K; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;, Spierings E; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;, Kipling D; Institute of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom; and., Randall KL; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;, Langley D; Immunology Division, Garvan Institute of Medical Research and., Roome B; Immunology Division, Garvan Institute of Medical Research and., Vazquez-Lombardi R; Immunology Division, Garvan Institute of Medical Research and., Rouet R; Immunology Division, Garvan Institute of Medical Research and., Hermes J; Immunology Division, Garvan Institute of Medical Research and., Chan TD; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia;, Brink R; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia;, Dunn-Walters DK; Department of Immunobiology, King's College London School of Medicine, London SE1 9RT, United Kingdom., Christ D; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia; d.christ@garvan.org.au chris.goodnow@anu.edu.au., Goodnow CC; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia; d.christ@garvan.org.au chris.goodnow@anu.edu.au.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Jun 24; Vol. 111 (25), pp. E2567-75. Date of Electronic Publication: 2014 May 12.
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
MeSH Terms: Autoantibodies/*immunology , B-Lymphocytes/*immunology , Clonal Anergy/*immunology , Germinal Center/*immunology , Immunoglobulin Variable Region/*immunology , Somatic Hypermutation, Immunoglobulin/*immunology, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Autoantibodies/genetics ; Female ; Glycosylation ; Humans ; Immunoglobulin D/genetics ; Immunoglobulin D/immunology ; Immunoglobulin M/genetics ; Immunoglobulin M/immunology ; Immunoglobulin Variable Region/genetics ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Somatic Hypermutation, Immunoglobulin/genetics