Authors: Rotman, J., Mom, C. H., Jordanova, E. S., de Gruijl, T. D., Kenter, G. G.
Contributors: Obstetrics and Gynaecology, CCA - Treatment and quality of life, Obstetrics and gynaecology, Medical oncology laboratory
Source:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
BMC Cancer
BMC cancer, 18(1):888. BioMed Central
BMC Cancer, 18(1). BioMed Central
Subject Terms: Immunotherapy, Cervical cancer, Durvalumab, Programmed cell death ligand 1, Checkpoint inhibitor, Local therapy, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Study Protocol, Intratumoural, Cancer Research, Genetics, Oncology, Immune system, medicine.medical_treatment, medicine, Antibody, biology.protein, biology, business.industry, business, medicine.disease, Lymph, Lymph node, medicine.anatomical_structure, Surgical oncology, Cancer research, Antibodies, Monoclonal/administration & dosage, Antineoplastic Agents, Immunological/administration & dosage, B7-H1 Antigen/antagonists & inhibitors, Clinical Protocols, Female, Humans, Injections, Intralesional, Lymphatic Metastasis, Molecular Targeted Therapy, Neoplasm Staging, Tumor Microenvironment/drug effects, Uterine Cervical Neoplasms/drug therapy
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http://link.springer.com/article/10.1186/s12885-018-4764-0
Authors: Rodell, Christopher B., Arlauckas, Sean P., Cuccarese, Michael F., Garris, Christopher S., Li, Ran, Ahmed, Maaz S., Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph
Source:
Nature biomedical engineering
Nature Biomedical Engineering, Vol. 2, No 8 (2018) pp. 578-588
Subject Terms: Article, macrophages, drug delivery, nanoparticles, imaging, cancer immunotherapy, Animals, Antineoplastic Agents/chemistry/pharmacology, Cell Line, Tumor, Humans, Imidazoles/chemistry/pharmacology, Immunotherapy/methods, Macrophages/drug effects/immunology, Mice, Nanoparticles/chemistry, Neoplasms/therapy, Toll-Like Receptor 7/agonists, Toll-Like Receptor 8/agonists, Tumor Microenvironment/drug effects/immunology, Computer Science Applications, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Biotechnology, Phenotype, Medicine, business.industry, business, Cancer immunotherapy, medicine.medical_treatment, Immunotherapy, Receptor, TLR7, Agonist, medicine.drug_class, Drug delivery, In vivo, Cancer research
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc3e6585cc6fc022f87758693ca063a
http://europepmc.org/articles/PMC6192054
Authors: Yan, D., Kowal, J., Akkari, L., Schuhmacher, A.J., Huse, J.T., West, B.L., Joyce, J.A.
Source:
Oncogene
Oncogene, vol. 36, no. 43, pp. 6049-6058
Subject Terms: Original Article, Cancer Research, Genetics, Molecular Biology, Cell cycle, Immunology, Vatalanib, Glioma, medicine.disease, medicine, Biology, Tumor microenvironment, Receptor Tyrosine Kinase Inhibition, Colony stimulating factor 1 receptor, Tyrosine kinase, Cancer research, Growth factor receptor, Aminopyridines/administration & dosage, Animals, Cell Line, Tumor, Cell Proliferation/drug effects, Disease Models, Animal, Drug Resistance, Neoplasm/genetics, Glioma/drug therapy, Glioma/genetics, Glioma/pathology, Humans, Mice, Protein Kinase Inhibitors/administration & dosage, Proto-Oncogene Proteins c-sis/genetics, Pyrroles/administration & dosage, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/genetics, Tumor Microenvironment/drug effects
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http://europepmc.org/articles/PMC5666319
Authors: Ayeni, Deborah, Miller, Braden, Kuhlmann, Alexandra, Ho, Ping-Chih, Robles-Oteiza, Camila, Gaefele, Mmaserame, Levy, Stellar, de Miguel, Fernando J., Perry, Curtis, Guan, Tianxia, Krystal, Gerald, Lockwood, William, Zelterman, Daniel, Homer, Robert, Liu, Zongzhi, Kaech, Susan, Politi, Katerina
Source:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Journal for immunotherapy of cancer, vol. 7, no. 1, pp. 172
Subject Terms: Research Article, Lung cancer, EGFR, Targeted therapies, Immunotherapies, Mouse models, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Animals, Antineoplastic Agents/therapeutic use, ErbB Receptors/genetics, ErbB Receptors/immunology, Erlotinib Hydrochloride/therapeutic use, Lung Neoplasms/drug therapy, Lung Neoplasms/genetics, Lung Neoplasms/immunology, Mice, Transgenic, Mutation, Oncogenes, Protein Kinase Inhibitors/therapeutic use, T-Lymphocytes/drug effects, T-Lymphocytes/immunology, Tumor Microenvironment/drug effects, Tumor Microenvironment/immunology, Cancer Research, Pharmacology, Oncology, Molecular Medicine, Immunology, Immunology and Allergy, Cancer research, Oncogene, medicine.disease, medicine, Tyrosine kinase, business.industry, business, Erlotinib, medicine.drug, Immune system, Tumor microenvironment, CD40, biology.protein, biology, Epidermal growth factor receptor, respiratory tract diseases
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http://europepmc.org/articles/PMC6617639
Contributors: School of Biological Sciences, Nanyang Technological University (NTU), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Université de Lausanne (UNIL), Singapore Ministry of Education [2014-T2-1-012, 2017-T1-002-103, 2015-T1-001-034], Lee Kong Chian School of Medicine, Nanyang Technological University Start-up Grant, Cheng, Hong Sheng
Source:
Molecular Cancer
Molecular Cancer, BioMed Central, 2019, 18, ⟨10.1186/s12943-019-0971-9⟩
Molecular Cancer (18), . (2019)
Molecular Cancer, Vol 18, Iss 1, Pp 1-19 (2019)
Molecular cancer, vol. 18, no. 1, pp. 51
Subject Terms: Cancer-associated fibroblast, Myeloid-derived suppressor cells, Tumor-associated macrophage, Nuclear receptors, Tumor microenvironment, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Médecine humaine et pathologie, Human health and pathology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Review, Animals, Antineoplastic Agents/therapeutic use, Humans, Neoplasms/drug therapy, Neoplasms/metabolism, Neoplasms/pathology, Receptors, Cytoplasmic and Nuclear/antagonists & inhibitors, Receptors, Cytoplasmic and Nuclear/metabolism, Signal Transduction, Stromal Cells/drug effects, Stromal Cells/metabolism, Tumor Microenvironment/drug effects, Cancer Research, Oncology, Molecular Medicine, Stromal cell, Receptor, Immune system, Cancer research, Biology, Myeloid-derived Suppressor Cell, Angiogenesis, Signal transduction
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https://hal.inrae.fr/hal-02620849
Authors: Olga Sedlakova, Maria Bartosova, Silvia Pastorekova, Monika Barathova, Martina Takacova, Sona Hudecova, Michal Pastorek, Luba Hunakova, Olga Krizanova, Jan Sedlak, Franck Dequiedt, Veronika Simko
Source:
International Journal of Oncology
Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy. International Journal of Oncology, 47(1), 51-60., Greece. (2015).
Subject Terms: Articles, sulforaphane, hypoxia, carbonic anhydrase IX, migration, chemoresistance, Anticarcinogenic Agents/pharmacology, Antigens, Neoplasm/genetics/metabolism, Carbonic Anhydrases/genetics/metabolism, Cell Hypoxia/drug effects, Cell Movement/drug effects, Cisplatin/pharmacology, Doxorubicin/pharmacology, Drug Resistance, Neoplasm/drug effects, Drug Synergism, Female, Gene Expression Regulation, Neoplastic/drug effects, Humans, Hypoxia-Inducible Factor 1, alpha Subunit/metabolism, Isothiocyanates/pharmacology, Ovarian Neoplasms/drug therapy/genetics/metabolism, Tumor Microenvironment/drug effects, Biochemistry, biophysics & molecular biology [Life sciences], Biochimie, biophysique & biologie moléculaire [Sciences du vivant], Cancer Research, Oncology, Oncogene, Pharmacology, Cell, medicine.anatomical_structure, medicine, Tumor progression, Tumor microenvironment, Ovarian tumor, Cancer cell, Cell cycle, Sulforaphane, chemistry.chemical_compound, chemistry, Biology
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http://europepmc.org/articles/PMC4485648
Authors: Miller, Miles A., Chandra, Ravi, Cuccarese, Michael F., Pfirschke, Christina, Engblom, Camilla, Stapleton, Shawn, Adhikary, Utsarga, Kohler, Rainer H., Mohan, James F., Pittet, Mikael J., Weissleder, Ralph
Source: Science Translational Medicine, Vol. 9, No 392 (2017) P. eaal0225
Subject Terms: General Medicine, Drug, media_common.quotation_subject, media_common, Radiation therapy, medicine.medical_treatment, medicine, business.industry, business, Adjuvant, Intravital microscopy, Cyclophosphamide, medicine.drug, Immunology, Tumor microenvironment, Cell culture, Extravasation, Cancer research, Article, Animals, Cell Count, Cell Line, Tumor, Chemistry, Pharmaceutical, Combined Modality Therapy, Cyclophosphamide/pharmacology/therapeutic use, Drug Delivery Systems, Extravasation of Diagnostic and Therapeutic Materials/pathology, Humans, Intravital Microscopy, Macrophages/drug effects/pathology/radiation effects, Mice, Nude, Nanoparticles/chemistry, Neoplasms/blood supply/drug therapy/radiotherapy, Permeability, Phagocytes/drug effects/pathology/radiation effects, Tumor Microenvironment/drug effects/radiation effects, Xenograft Model Antitumor Assays
Access URL: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d44c45266c7c925de561a4c32c1d384
Authors: Cuccarese, Michael F., Dubach, J. Matthew, Pfirschke, Christina, Engblom, Camilla, Garris, Christopher, Miller, Miles A., Pittet, Mikael J., Weissleder, Ralph
Source:
Nature Communications, Vol. 8 (2017) P. 14293
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Subject Terms: Aminopyridines/pharmacology/therapeutic use, Animals, Antineoplastic Agents/pharmacology/therapeutic use, Carcinoma, Lewis Lung/diagnostic imaging/drug therapy/immunology/pathology, Cell Line, Tumor, Female, Humans, Imaging, Three-Dimensional/methods, Lung/diagnostic imaging/pathology, Lung Neoplasms/diagnostic imaging/drug therapy/immunology/pathology, Macrophage Colony-Stimulating Factor/immunology/metabolism, Macrophages/drug effects/immunology, Mice, Inbred C57BL, Microscopy, Confocal/methods, Fluorescence/methods, Nanoparticles/administration & dosage/chemistry, Perfusion/methods, Pyrroles/pharmacology/therapeutic use, RAW 264.7 Cells, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/antagonists & inhibitors/immunology/metabolism, Signal Transduction/drug effects, Tomography, X-Ray Computed, Treatment Outcome, Tumor Burden/drug effects/immunology, Tumor Microenvironment/drug effects/immunology, Xenograft Model Antitumor Assays, Science, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Cancer research, Immune system, Lung, medicine.anatomical_structure, medicine, Blockade, business.industry, business, Receptor, Immunology, Drug delivery, Cancer, medicine.disease, Macrophage infiltration, Article, stomatognathic system, hormones, hormone substitutes, and hormone antagonists, skin and connective tissue diseases
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https://archive-ouverte.unige.ch/unige:154058
Authors: Matas-Céspedes, Alba, Vidal-Crespo, Anna, Rodriguez, Vanina, Villamor, Neus, Delgado, Julio, Giné, Eva, Roca-Ho, Heleia, Menéndez, Pablo, Campo, Elias, López-Guillermo, Armando, Colomer, Dolors, Roué, Gael, Wiestner, Adrian, Parren, Paul W H I, Doshi, Parul, Van Bueren, Jeroen Lammerts, Pérez-Galán, Patricia
Source: Matas-Céspedes, A, Vidal-Crespo, A, Rodriguez, V, Villamor, N, Delgado, J, Giné, E, Roca-Ho, H, Menéndez, P, Campo, E, López-Guillermo, A, Colomer, D, Roué, G, Wiestner, A, Parren, P W H I, Doshi, P, Van Bueren, J L & Pérez-Galán, P 2017, ' The human CD38 monoclonal antibody daratumumab shows antitumor activity and hampers leukemia-microenvironment interactions in chronic lymphocytic leukemia ', Clinical Cancer Research, vol. 23, no. 6, pp. 1493-1505 . https://doi.org/10.1158/1078-0432.CCR-15-2095
Subject Terms: Article, Cancer Research, Oncology, Daratumumab, Peripheral blood mononuclear cell, Antibody-dependent cell-mediated cytotoxicity, Leukemia, medicine.disease, medicine, Chronic lymphocytic leukemia, Immunology, Biology, CD38, Tumor microenvironment, Monoclonal antibody, medicine.drug_class, ADP-ribosyl Cyclase 1/genetics, Animals, Antibodies, Monoclonal/administration & dosage, Cell Line, Tumor, Cytophagocytosis/drug effects, Humans, Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy, Matrix Metalloproteinase 9/genetics, Mice, Tumor Microenvironment/drug effects, Xenograft Model Antitumor Assays, hemic and lymphatic diseases, immune system diseases, neoplasms
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https://europepmc.org/articles/PMC5354986/
Source: Araujo B de Lima , V , Borch , A , Hansen , M , Draghi , A , Spanggaard , I , Rohrberg , K , Reker Hadrup , S , Lassen , U & Svane , I M 2020 , ' Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition : impact on clinical outcome ' , Cytotherapy , vol. 22 , no. 4 , pp. 204-213 .
Index Terms: Adult, Aged, B7-H1 Antigen/antagonists & inhibitors, Biopsy, CD8-Positive T-Lymphocytes/immunology, Female, Follow-Up Studies, Humans, Immunologic Factors/pharmacology, Immunotherapy/methods, Lymphocytes, Tumor-Infiltrating/drug effects, Male, Middle Aged, Molecular Targeted Therapy/methods, Neoplasms/pathology, Phenotype, Programmed Cell Death 1 Receptor/antagonists & inhibitors, Treatment Outcome, Tumor Microenvironment/drug effects, article
Authors: Zhang, Shirley X
Source: Trends in cancer; vol 4, iss 4, 268-271; 2405-8025
Index Terms: Antineoplastic Agents: pharmacology, therapeutic use, Biomarkers, Tumor: analysis, Biophysics: methods, trends, Elasticity Imaging Techniques, Extracellular Matrix: drug effects, pathology, Humans, Medical Oncology: methods, Neoplasms: diagnosis, etiology, therapy, Oncolytic Virotherapy: methods, Treatment Outcome, Tumor Microenvironment: drug effects, article
Index Terms: Adenoviridae/*genetics/metabolism, Animals, Bacterial Proteins/genetics/immunology/*therapeutic use, Cell Differentiation/drug effects, Cell Line, Tumor, Cytokines/metabolism, Female, Genetic Therapy, Genetic Vectors, Humans, Mice, Nude, Neuroendocrine Tumors/immunology/*therapy, Neutrophils/drug effects/metabolism, Oncolytic Virotherapy, Oncolytic Viruses/*genetics/metabolism, Recombination, Genetic, Tumor Microenvironment/drug effects/immunology, Virulence Factors/metabolism, Xenograft Model Antitumor Assays, Cancer and Oncology, Cancer och onkologi, Immunology in the medical area, Immunologi inom det medicinska området, Article in journal, info:eu-repo/semantics/article, text
URL:
Molecular Therapy, 1525-0016, 2013, 21:11, s. 2008-2018
Source: Haematologica, 97 (4
Index Terms: Cancérologie, Actins -- metabolism, Antibodies, Monoclonal -- immunology -- metabolism, Antineoplastic Agents -- pharmacology -- therapeutic use, Apoptosis -- drug effects, Cell Communication -- drug effects, Cell Movement -- drug effects, Cell Survival -- drug effects, Chemokine CXCL12 -- pharmacology, Coculture Techniques, Heterocyclic Compounds -- pharmacology -- therapeutic use, Humans, Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy -- metabolism, Leukocytes, Mononuclear -- drug effects -- metabolism, Mesenchymal Stromal Cells -- drug effects -- metabolism, Protein Binding -- drug effects -- immunology, Protein Multimerization -- drug effects, Receptors, CXCR4 -- antagonists & inhibitors -- immunology -- metabolism, Tumor Microenvironment -- drug effects, Amd3100, Apoptosis, Chronic lymphocytic leukemia, Mesenchymal stromal cells, Microenvironment, Nurse-like cells, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
URL: