Authors: Neganova, I, Tilgner, K, Buskin, A, Paraskevopoulou, I, Atkinson, S P, Peberdy, D, Passos, J F, Lako, M
Source: Cell Death & Disease
Subject Terms: Original Article, biological phenomena, cell phenomena, and immunity
Access URL:
https://explore.openaire.eu/search/publication?articleId=pmid________::94eead9f2d7c05f438ece56fb214a0fb
http://europepmc.org/articles/PMC4260724
Authors: Markiewicz, E., Tilgner, K., Wetering, M. van de, Clevers, J.C., Dorobek, M., Haumanowa-Petrusewicz, I., Ramaekers, F.C.S., Broers, J.L.V., Blankesteijn, W.M., Salpingidou, G., Wilson, R.G., Ellis, J.A., Hutchison, C.J.
Contributors: Hubrecht Institute for Developmental Biology and Stem Cell Research
Source: EMBO Journal, 25, 3275-3285. Nature Publishing Group
Access URL:
https://explore.openaire.eu/search/publication?articleId=narcis______::38e67cd915854fcf1ce90e0e37c9e49d
https://pure.knaw.nl/portal/en/publications/1c6da2cd-303a-4e10-a095-e3b7f0c3bfb9
Authors: Tilgner, K, Neganova, I, Moreno-Gimeno, I, AL-Aama, J Y, Burks, D, Yung, S, Singhapol, C, Saretzki, G, Evans, J, Gorbunova, V, Gennery, A, Przyborski, S, Stojkovic, M, Armstrong, L, Jeggo, P, Lako, M
Source: Cell Death & Differentiation; Aug2013, Vol. 20 Issue 8, p1089-1100, 12p, 1 Color Photograph, 1 Chart, 4 Graphs
Subject Terms: CELLS, DNA, NUCLEIC acids, GENES, BIOCHEMICAL genetics
Authors: Collier AJ; Epigenetics Programme, Babraham Institute, Cambridge, UK.; Department of Biological Chemistry, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Bendall A; Epigenetics Programme, Babraham Institute, Cambridge, UK., Fabian C; Epigenetics Programme, Babraham Institute, Cambridge, UK., Malcolm AA; Epigenetics Programme, Babraham Institute, Cambridge, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK., Tilgner K; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Semprich CI; Epigenetics Programme, Babraham Institute, Cambridge, UK., Wojdyla K; Epigenetics Programme, Babraham Institute, Cambridge, UK., Nisi PS; Epigenetics Programme, Babraham Institute, Cambridge, UK., Kishore K; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Roamio Franklin VN; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Mirshekar-Syahkal B; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., D'Santos C; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Plath K; Department of Biological Chemistry, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Yusa K; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Stem Cell Genetics, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan., Rugg-Gunn PJ; Epigenetics Programme, Babraham Institute, Cambridge, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Source: Science advances [Sci Adv] 2022 Mar 25; Vol. 8 (12), pp. eabk0013. Date of Electronic Publication: 2022 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Authors: El-Khairi R; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Department of Surgery, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Olszanowski E; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), CONICET-Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina., Muraro D; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Madrigal P; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Tilgner K; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Chhatriwala M; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Vyas S; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Chia CY; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Vallier L; Wellcome Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Hinxton, Cambridge, UK; Department of Surgery, University of Cambridge, Cambridge, UK. Electronic address: lv225@cam.ac.uk., Rodríguez-Seguí SA; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), CONICET-Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina; Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina. Electronic address: srodriguez@fbmc.fcen.uba.ar.
Source: Stem cell reports [Stem Cell Reports] 2021 Sep 14; Vol. 16 (9), pp. 2289-2304. Date of Electronic Publication: 2021 Aug 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE
MeSH Terms: Models, Biological*, Cell Differentiation/*genetics , Hepatocyte Nuclear Factor 1-beta/*genetics , Induced Pluripotent Stem Cells/*cytology , Induced Pluripotent Stem Cells/*metabolism , Organogenesis/*genetics , Pancreas/*embryology , Pancreas/*metabolism, Biomarkers ; CRISPR-Cas Systems ; Cell Lineage/genetics ; Diabetes Mellitus/etiology ; Disease Susceptibility ; Fluorescent Antibody Technique ; Gene Editing ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Haploinsufficiency ; Hepatocyte Nuclear Factor 1-beta/metabolism ; Humans ; Immunophenotyping ; Insulin-Secreting Cells/metabolism ; Signal Transduction
Authors: Loonat AA; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Martin ED; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Sarafraz-Shekary N; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Tilgner K; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Hertz NT; University of California-San Francisco, San Francisco, California, USA., Levin R; University of California-San Francisco, San Francisco, California, USA., Shokat KM; University of California-San Francisco, San Francisco, California, USA., Burlingame AL; University of California-San Francisco, San Francisco, California, USA., Arabacilar P; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Uddin S; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Thomas M; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Marber MS; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom., Clark JE; School of Cardiovascular Medicine and Science, British Heart Foundation (BHF) Centre, King's College London, London, United Kingdom.
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Dec; Vol. 33 (12), pp. 13131-13144. Date of Electronic Publication: 2019 Oct 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
MeSH Terms: Calcium-Binding Proteins/*metabolism , Calpain/*metabolism , Mitogen-Activated Protein Kinase 12/*metabolism , Ventricular Remodeling/*physiology, Animals ; Calpain/genetics ; Echocardiography ; Electrophoresis, Polyacrylamide Gel ; HEK293 Cells ; Humans ; Immunohistochemistry ; Male ; Mice ; Mitogen-Activated Protein Kinase 12/genetics ; Phosphorylation ; Protein Isoforms ; Tandem Mass Spectrometry ; Ventricular Remodeling/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism
Authors: Jiang Y; Institute of Genetic Medicine and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom; Soochow University, Su Zhou, China; Princess Al Jawhara Center of Excellence in Research, King Abdulaziz University, Jeddah, Saudi Arabia; Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic; Institute of Cardiovascular Science, Manchester Academic Health Science Centre, CoreTechnology Facility, Manchester, United Kingdom; School of Biomedical Sciences, University of Durham, Durham, United Kingdom; Department of Human Genetics, University of Kragujevac, Kragujevac, Serbia., Habibollah S, Tilgner K, Collin J, Barta T, Al-Aama JY, Tesarov L, Hussain R, Trafford AW, Kirkwood G, Sernagor E, Eleftheriou CG, Przyborski S, Stojković M, Lako M, Keavney B, Armstrong L
Source: Stem cells translational medicine [Stem Cells Transl Med] 2014 Apr; Vol. 3 (4), pp. 416-23. Date of Electronic Publication: 2014 Mar 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2157-6564 (Print) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
Authors: Li M; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Yu JSL; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Tilgner K; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Ong SH; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Koike-Yusa H; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Yusa K; Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. Electronic address: ky1@sanger.ac.uk.
Source: Cell reports [Cell Rep] 2018 Jul 10; Vol. 24 (2), pp. 489-502.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
MeSH Terms: Gene Knockout Techniques* , Genome*, Clustered Regularly Interspaced Short Palindromic Repeats/*genetics , Mechanistic Target of Rapamycin Complex 1/*metabolism , Pluripotent Stem Cells/*cytology , Pluripotent Stem Cells/*metabolism, Animals ; Cell Differentiation/genetics ; Cell Self Renewal ; Gene Expression Regulation, Developmental ; Glycogen Synthase Kinase 3/metabolism ; Mice ; Mice, Knockout ; Models, Biological ; Mouse Embryonic Stem Cells ; Phenotype ; Transcriptome/genetics
Authors: Melguizo-Sanchis D; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Xu Y; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Taheem D; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Yu M; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Tilgner K; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Barta T; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Gassner K; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Anyfantis G; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Wan T; The Ageing Biology Centre. Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK., Elango R; Princess Al Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Alharthi S; Princess Al Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., El-Harouni AA; Princess Al Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Przyborski S; Department of Bioscience, Durham University, Durham, UK., Adam S; Hematology Department, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Medicine, Duke University Medical Center, Durham, USA., Saretzki G; The Ageing Biology Centre. Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK., Samarasinghe S; Department of Hematology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Armstrong L; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Lako M; Institute of Genetic Medicine, Newcastle University, Newcastle, UK. majlinda.lako@ncl.ac.uk.
Source: Cell death & disease [Cell Death Dis] 2018 Jan 26; Vol. 9 (2), pp. 128. Date of Electronic Publication: 2018 Jan 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis
MeSH Terms: Cell Differentiation*/drug effects , Models, Biological* , Telomere Shortening*/drug effects, Anemia, Aplastic/*pathology , Hematopoietic Stem Cells/*pathology , Induced Pluripotent Stem Cells/*pathology, Benzoates/pharmacology ; Case-Control Studies ; Cell Line ; Cell Proliferation/drug effects ; Colony-Forming Units Assay ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Hematopoietic Stem Cells/metabolism ; Humans ; Hydrazines/pharmacology ; Induced Pluripotent Stem Cells/drug effects ; Induced Pluripotent Stem Cells/metabolism ; Pyrazoles/pharmacology ; Telomerase/metabolism ; Telomere/metabolism
Authors: Meader E; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Barta T; Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czech Republic., Melguizo-Sanchis D; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Tilgner K; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Montaner D; Centro de Investigación Príncipe Felipe, Valencia, Spain., El-Harouni AA; Princess Al Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Armstrong L; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Lako M; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2018 Jan; Vol. 36 (1), pp. 55-64. Date of Electronic Publication: 2017 Oct 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Epithelial-Mesenchymal Transition/*genetics , Hematopoietic Stem Cells/*metabolism , MicroRNAs/*genetics , Pluripotent Stem Cells/*metabolism, Cell Differentiation ; Down-Regulation ; Humans
Authors: Zhu L; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Gomez-Duran A; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK.; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Saretzki G; Institute for Ageing and Health, Newcastle University, Newcastle NE1 3BZ, England, UK., Jin S; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Tilgner K; Wellcome Trust-Medical Research Council Stem Cell Institute, Hinxton, Cambridge CB10 1SA, England, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, England, UK., Melguizo-Sanchis D; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Anyfantis G; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Al-Aama J; Princess Al Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Vallier L; Wellcome Trust-Medical Research Council Stem Cell Institute, Hinxton, Cambridge CB10 1SA, England, UK., Chinnery P; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK., Lako M; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK lyle.armstrong@ncl.ac.uk majlinda.lako@ncl.ac.uk., Armstrong L; Institute of Genetic Medicine, Newcastle University, Newcastle NE1 3BZ, England, UK lyle.armstrong@ncl.ac.uk majlinda.lako@ncl.ac.uk.
Source: The Journal of cell biology [J Cell Biol] 2016 Oct 24; Vol. 215 (2), pp. 187-202. Date of Electronic Publication: 2016 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE
MeSH Terms: Cell Differentiation* , Cell Lineage*, Induced Pluripotent Stem Cells/*cytology , Mitochondrial Proteins/*metabolism , Neural Plate/*cytology , Transcription Factors/*metabolism, Apoptosis/genetics ; Base Sequence ; Cell Line ; Cell Movement/genetics ; Cell Survival/genetics ; Cellular Reprogramming/genetics ; DNA-Binding Proteins ; Gene Expression Profiling ; Human Embryonic Stem Cells/cytology ; Human Embryonic Stem Cells/metabolism ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Mitochondria/metabolism ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/genetics ; Transforming Growth Factor beta/metabolism
Authors: Tilgner K; Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom; NESCI, Newcastle University, Newcastle, United Kingdom., Neganova I, Singhapol C, Saretzki G, Al-Aama JY, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P, Lako M
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2013 Sep; Vol. 31 (9), pp. 2015-23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Models, Biological*, DNA Repair Enzymes/*deficiency , DNA-Binding Proteins/*deficiency , Hematopoietic Stem Cells/*cytology , Hematopoietic Stem Cells/*metabolism , Induced Pluripotent Stem Cells/*metabolism, Base Sequence ; Cell Differentiation ; Cell Line ; Cell Survival ; DNA Breaks, Double-Stranded ; DNA End-Joining Repair ; DNA Repair Enzymes/metabolism ; DNA-Binding Proteins/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Molecular Sequence Data
Authors: Yung SK; Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom., Tilgner K, Ledran MH, Habibollah S, Neganova I, Singhapol C, Saretzki G, Stojkovic M, Armstrong L, Przyborski S, Lako M
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2013 May; Vol. 31 (5), pp. 1022-9.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Cellular Reprogramming/*physiology , Fanconi Anemia/*pathology , Fanconi Anemia Complementation Group Proteins/*metabolism , Hematopoietic Stem Cells/*pathology , Induced Pluripotent Stem Cells/*pathology, Cell Differentiation/physiology ; Fanconi Anemia/genetics ; Fanconi Anemia/metabolism ; Fanconi Anemia Complementation Group Proteins/genetics ; Genetic Therapy ; Hematopoietic Stem Cells/cytology ; Hematopoietic Stem Cells/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism
Authors: Jiang Y; Institute of Genetic Medicine, Newcastle University, Newcastle, UK., Cowley SA, Siler U, Melguizo D, Tilgner K, Browne C, Dewilton A, Przyborski S, Saretzki G, James WS, Seger RA, Reichenbach J, Lako M, Armstrong L
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2012 Apr; Vol. 30 (4), pp. 599-611.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Models, Biological*, Cell Culture Techniques/*methods , Granulomatous Disease, Chronic/*pathology , Induced Pluripotent Stem Cells/*pathology, Cell Differentiation ; Cell Line ; Cytokines/metabolism ; Humans ; Karyotyping ; Kinetics ; Macrophages/cytology ; Macrophages/metabolism ; Monocytes/cytology ; Monocytes/metabolism ; NADPH Oxidases/metabolism ; Phenotype ; Reactive Oxygen Species/metabolism
Authors: Armstrong L; Institute of Human Genetics, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom. Lyle.Armstrong@ncl.ac.uk, Tilgner K, Saretzki G, Atkinson SP, Stojkovic M, Moreno R, Przyborski S, Lako M
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2010 Apr; Vol. 28 (4), pp. 661-73.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Stress, Physiological*, Embryonic Stem Cells/*metabolism , Induced Pluripotent Stem Cells/*metabolism , Mitochondria/*metabolism, Cell Culture Techniques ; Cell Differentiation ; Cells, Cultured ; Humans ; Induced Pluripotent Stem Cells/cytology ; Karyotyping ; Reactive Oxygen Species/metabolism
Authors: Tilgner K; North East Stem Cell Institute, Newcastle University, International Centre for Life, NE1 3BZ, United Kingdom., Atkinson SP, Yung S, Golebiewska A, Stojkovic M, Moreno R, Lako M, Armstrong L
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2010 Jan; Vol. 28 (1), pp. 84-92.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Cell Differentiation*/genetics , Flow Cytometry* , Promoter Regions, Genetic*, Cell Separation/*methods , DEAD-box RNA Helicases/*genetics , Embryonic Stem Cells/*metabolism , Germ Cells/*metabolism , Green Fluorescent Proteins/*biosynthesis, Cell Line ; Chromatin Assembly and Disassembly ; Female ; Gene Expression Profiling/methods ; Gene Expression Regulation, Developmental ; Green Fluorescent Proteins/genetics ; Humans ; Meiosis ; Microscopy, Confocal ; Oligonucleotide Array Sequence Analysis ; Recombinant Proteins/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors ; Transfection
Authors: Tilgner K; The School of Biological and Biomedical Sciences, The University of Durham, Durham, UK., Wojciechowicz K, Jahoda C, Hutchison C, Markiewicz E
Source: Journal of cell science [J Cell Sci] 2009 Feb 01; Vol. 122 (Pt 3), pp. 401-13. Date of Electronic Publication: 2009 Jan 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9533 (Print) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE
MeSH Terms: Adipocytes/*metabolism , Adipogenesis/*physiology , Lamin Type A/*metabolism , Membrane Proteins/*metabolism , Nuclear Proteins/*metabolism , beta Catenin/*metabolism, Adipocytes/cytology ; Animals ; Cell Line ; Cell Nucleus/metabolism ; Cytoplasm/metabolism ; Fibroblasts/metabolism ; Gene Knockdown Techniques ; Humans ; Membrane Proteins/genetics ; Mice ; Nuclear Proteins/genetics ; PPAR gamma/metabolism ; RNA, Small Interfering/metabolism ; beta Catenin/genetics
Authors: Tilgner K; North East Institute for Stem Cell Research, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom., Atkinson SP, Golebiewska A, Stojkovic M, Lako M, Armstrong L
Source: Stem cells (Dayton, Ohio) [Stem Cells] 2008 Dec; Vol. 26 (12), pp. 3075-85. Date of Electronic Publication: 2008 Sep 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE
MeSH Terms: Cell Culture Techniques/*methods , Cell Separation/*methods , Germ Cells/*cytology, Animals ; Cell Differentiation ; Cell Line ; Chromatin/metabolism ; CpG Islands ; Epigenesis, Genetic ; Flow Cytometry ; Germ Cells/metabolism ; Humans ; Mice ; Microscopy, Confocal/methods ; Reverse Transcriptase Polymerase Chain Reaction ; Transfection