Search Results - "Receptor, erbB-2 -- metabolism"

1

Non-phosphorylated Tyr-1248 form of human epidermal growth factor receptor 2 (HER2) predicts resistance to trastuzumab therapy and poor disease-free survival of HER2- positive breast cancer patients

Authors: Ramić, Snježana, Paić, Frane, Smajlbegović, Velda, Perić Balja, Melita, Hiršl, Lea, Marton, Ingrid, Knežević, Fabijan

Source: Croatian Medical Journal
Volume 63
Issue 2

Subject Terms: General Medicine, BIOMEDICINA I ZDRAVSTVO. Temeljne medicinske znanosti, BIOMEDICINE AND HEALTHCARE. Basic Medical Sciences, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Onkologija, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Oncology, Breast Neoplasms / drug therapy, Disease-Free Survival, Female, Humans, Middle Aged, Receptor, ErbB-2 / genetics, Receptor, ErbB-2 / metabolism, Trastuzumab / therapeutic use

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https://hrcak.srce.hr/279008

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2

Molecular and Functional Characterization of Circulating Tumor Cells: From Discovery to Clinical Application

Authors: Zahra Eslami-S, Luis Enrique Cortés-Hernández, Klaus Pantel, Catherine Alix-Panabières

Contributors: Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg] (UKE)

Source: Clinical Chemistry
Clinical Chemistry, American Association for Clinical Chemistry, 2020, 66 (1), pp.97-104. ⟨10.1373/clinchem.2019.303586⟩

Subject Terms: Biochemistry (medical), Clinical Biochemistry, Metastasis, medicine.disease, medicine, Circulating tumor cell, Clinical information, business.industry, business, Cancer, Computational biology, Functional studies, Transcriptome, Proteome, Liquid biopsy, Tissue biopsies, MESH: Biomarkers, Tumor / genetics, Biomarkers, Tumor / metabolism, Humans, Liquid Biopsy, Neoplastic Cells, Circulating / metabolism, MESH: Neoplastic Cells, Circulating / pathology, Programmed Cell Death 1 Receptor / genetics, Programmed Cell Death 1 Receptor / metabolism, Proteome / metabolism, MESH: Proto-Oncogene Proteins B-raf / genetics, Receptor, ErbB-2 / genetics, Receptor, ErbB-2 / metabolism, ras Proteins / genetics, [SDV.CAN]Life Sciences [q-bio]/Cancer

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https://doi.org/10.1373/clinchem.2019.303586

3

Tumor-infiltrating lymphocytes are associated with poor prognosis in invasive lobular breast carcinoma

Authors: Jean-Christophe Tille, André Filipe Vieira, Youlia Kirova, François-Clément Bidard, Laëtitia Furhmann, Lounes Djerroudi, Caroline Saint-Martin, Matthieu Carton, Anne Vincent-Salomon, F Reyal, Anne Tardivon

Contributors: Hôpitaux Universitaires de Genève (HUG), Institut Curie [Paris], Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Universidade do Porto, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Fundo Regional para a Ciência e Tecnologia, FRCT, Funding AFV received support from a Mayent-Rothschild fellowship from Institut Curie, France and IPATIMUP/Fundação para a Ciência e Tecnologia, Portugal.

Source: Modern Pathology
Modern Pathology, Nature Publishing Group: Open Access Hybrid Model Option B, 2020, 33 (11), pp.2198-2207. ⟨10.1038/s41379-020-0561-9⟩
Modern pathology, Vol. 33, No 11 (2020) pp. 2198-2207

Subject Terms: [SDV]Life Sciences [q-bio], chemical and pharmacologic phenomena, hemic and immune systems, ddc:616.07, Age Factors, Breast Neoplasms / immunology, Breast Neoplasms / metabolism, Breast Neoplasms / mortality, Breast Neoplasms / pathology, Carcinoma, Lobular / immunology, Carcinoma, Lobular / metabolism, Carcinoma, Lobular / mortality, Carcinoma, Lobular / pathology, Female, Humans, Lymphocytes, Tumor-Infiltrating / immunology, Lymphocytes, Tumor-Infiltrating / pathology, Middle Aged, Prognosis, Receptor, ErbB-2 / metabolism, Receptors, Estrogen / metabolism, Receptors, Progesterone / metabolism, Retrospective Studies, Survival Rate, Pathology and Forensic Medicine, Invasive Lobular Breast Carcinoma, Survival analysis, Medicine, business.industry, business, Invasive lobular carcinoma, medicine.disease, Tumor-infiltrating lymphocytes, Nottingham Prognostic Index, Internal medicine, medicine.medical_specialty, Lymph node, medicine.anatomical_structure, Pathology, Biomarker (medicine), Oncology, Estrogen receptor, skin and connective tissue diseases

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https://hal.archives-ouvertes.fr/hal-03032297

4

Uloga inhibitora CDK4/6 u liječenju hormonski ovisnoga metastatskog raka dojke negativnog na HER-2

Authors: Ban, Marija, Strikić, Ante, Petrić Miše, Branka, Vrdoljak, Eduard

Source: Liječnički vjesnik
Volume 141
Issue 1-2

Subject Terms: TUMORI DOJKE – farmakoterapija, metabolizam, patologija, smrtnost, HORMONSKI OVISNI TUMORI – farmakoterapija, metabolizam, patologija, smrtnost, PROTUTUMORSKI LIJEKOVI – farmakologija, neželjeni učinci, terapijska primjena, RECEPTOR ERBB-2 – metabolizam, CIKLIN OVISNA KINAZA 4 – antagonisti i inhibitori, metabolizam, CIKLIN OVISNA KINAZA 6 – antagonisti i inhibitori, metabolizam, AROMATOZNI INHIBITORI – terapijska primjena, FULVESTRANT – terapijska primjena, INHIBITORI PROTEINSKE KINAZE – neželjeni učinci, terapijska primjena, TUMORSKE METASTAZE, PREŽIVLJENJE BEZ PROGRESIJE BOLESTI, BREAST NEOPLASMS – drug therapy, metabolism, mortality, pathology, NEOPLASMS, HORMONE-DEPENDENT – drug therapy, metabolism, mortality, pathology, ANTINEOPLASTIC AGENTS – adverse effects, pharmacology, therapeutic use, RECEPTOR, ERBB-2 – metabolism, CYCLIN-DEPENDENT KINASE 4 – antagonists and inhibitors, metabolism, CYCLIN-DEPENDENT KINASE 6 – antagonists and inhibitors, metabolism, AROMATOZNI INHIBITORI – therapeutic use, FULVESTRANT – therapeutic use, PROTEIN KINASE INHIBITORS – adverse effects, therapeutic use, NEOPLASM METASTASIS, PROGRESSION-FREE SURVIVAL, tumori dojke, hormonski ovisni tumori, protutumorski lijekovi, ERBB2 receptori

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https://hrcak.srce.hr/218766

5

Clinical and pharmacokinetic study of sunitinib and docetaxel in women with advanced breast cancer

Authors: L. Verkh, Carla Giorgetti, Gabriella Mariani, Annelie Liljegren, Kenneth A. Kern, Fatima Cardoso, Luca Gianni, Xin Huang, Ahmad Awada, Jonas Bergh, Lucia Viganò

Source: Breast, 21 (4

Subject Terms: General Medicine, Surgery, Docetaxel, medicine.drug, medicine, business.industry, business, Pharmacokinetics, Internal medicine, medicine.medical_specialty, Neutropenia, medicine.disease, Sunitinib, Tyrosine-kinase inhibitor, medicine.drug_class, Oncology, Adjuvant, medicine.medical_treatment, Anthracycline, Cancer, Cancérologie, Adult, Aged, Antineoplastic Agents -- administration & dosage -- adverse effects -- pharmacokinetics, Antineoplastic Combined Chemotherapy Protocols -- pharmacokinetics -- therapeutic use, Breast Neoplasms -- drug therapy -- metabolism, Carcinoma, Ductal, Breast -- drug therapy -- metabolism, Carcinoma, Lobular -- drug therapy -- metabolism, Drug Administration Schedule, Drug Interactions, Feasibility Studies, Female, Humans, Indoles -- administration & dosage -- adverse effects -- pharmacokinetics, Middle Aged, Neoplasm Recurrence, Local -- drug therapy, Pyrroles -- administration & dosage -- adverse effects -- pharmacokinetics, Receptor, erbB-2 -- metabolism, Taxoids -- administration & dosage -- adverse effects -- pharmacokinetics, Treatment Outcome, Advanced breast cancer, Tyrosine kinase inhibitor, urologic and male genital diseases, female genital diseases and pregnancy complications

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https://doi.org/10.1016/j.breast.2012.01.012

6

The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature

Authors: Jean-Jacques Lafitte, Marianne Paesmans, Jean-Paul Sculier, Anne-Pascale Meert, Philippe Delmotte, Céline Mascaux, Thierry Berghmans, Jean-Marc Verdebout, Benoît Martin

Source: British Journal of Cancer
British Journal of Cancer, 89 (6

Subject Terms: Review, lung cancer, systematic review, HER-2/neu, p185, c-erbB2, survival, prognostic factor, Cancer Research, Oncology, Immunology, Survival rate, Respiratory disease, medicine.disease, medicine, MEDLINE, Carcinoma, business.industry, business, Hazard ratio, Lung, medicine.anatomical_structure, Adenocarcinoma, Lung cancer, Internal medicine, medicine.medical_specialty, Sciences bio-médicales et agricoles, Adenocarcinoma -- metabolism, Adenocarcinoma -- mortality, Carcinoma, Non-Small-Cell Lung -- metabolism, Carcinoma, Non-Small-Cell Lung -- mortality, Carcinoma, Small Cell -- metabolism, Carcinoma, Small Cell -- mortality, Humans, Lung Neoplasms -- metabolism, Lung Neoplasms -- mortality, Prognosis, Receptor, erbB-2 -- metabolism, Sensitivity and Specificity, Survival Rate, Tumor Markers, Biological -- metabolism, Prognostic factor, Survival, Systematic review

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http://europepmc.org/articles/PMC2376951

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7

Cytotoxic T-cell precursor frequencies to HER-2 (369 – 377) in patients with HER-2/neu-positive epithelial tumours

Authors: Ioannis Missitzis, Sonia A. Perez, Constantin N. Baxevanis, Michael Papamichail, Hartmut Echner, E. G. Iliopoulou, Panagiota A. Sotiropoulou, V Voelter

Source: British Journal of Cancer, 89 (6
British Journal of Cancer

Subject Terms: Cancer Research, Oncology, Cancer, medicine.disease, medicine, Cellular immunity, Cytotoxic T cell, CTL, Population, education.field_of_study, education, Prostate cancer, Immunology, Immune system, business.industry, business, Major histocompatibility complex, biology.protein, biology, Sciences bio-médicales et agricoles, Adult, Aged, Cell Division, Cytokines -- metabolism, Dendritic Cells -- immunology, Dose-Response Relationship, Immunologic, Enzyme-Linked Immunosorbent Assay, Female, HLA-A Antigens -- immunology, HLA-A2 Antigen -- immunology, HLA-A3 Antigen -- immunology, Humans, Immunization, Immunophenotyping, Interferon-gamma -- biosynthesis, Leukocytes, Mononuclear -- cytology -- drug effects -- immunology, Male, Middle Aged, Neoplasms -- immunology, Peptide Fragments -- immunology, Receptor, erbB-2 -- metabolism, T-Lymphocytes, Cytotoxic -- immunology, Molecular and Cellular Pathology, HLA-A3, HLA-A26, cancer patients, prostate cancer, T-cell precursor frequencies, HER-2/neu peptides

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https://doi.org/10.1038/sj.bjc.6601244

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8

Safety and efficacy of everolimus with exemestane vs. Exemestane alone in elderly patients with HER2-negative, hormone receptor-positive breast cancer in BOLERO-2

Source: Clinical breast cancer, 13 (6

Subject Terms: Cancérologie, Aged, Aged, 80 and over, Androstadienes -- administration & dosage, Antineoplastic Combined Chemotherapy Protocols -- therapeutic use, Breast Neoplasms -- drug therapy -- metabolism -- mortality -- pathology, Female, Follow-Up Studies, Humans, International Agencies, Neoplasm Metastasis, Neoplasm Recurrence, Local -- drug therapy -- pathology, Neoplasm Staging, Prognosis, Receptor, ErbB-2 -- metabolism, Receptors, Estrogen -- metabolism, Receptors, Progesterone -- metabolism, Safety, Sirolimus -- administration & dosage -- analogs & derivatives, Survival Rate, Advanced breast cancer, Endocrine resistance, Geriatric, Progression-free survival, Cancer Research, Oncology, Tolerability, Breast cancer, medicine.disease, medicine, business.industry, business, Gynecology, medicine.medical_specialty, Population, education.field_of_study, education, Aromatase inhibitor, medicine.drug_class, Exemestane, chemistry.chemical_compound, chemistry, Everolimus, medicine.drug, Internal medicine, Hazard ratio

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http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/195356

9

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

Authors: Zoltan Szallasi, Søren Brunak, Lajos Pusztai, Andrea L. Richardson, Aron Charles Eklund, Christos Sotiriou, Christine Desmedt, Qiyuan Li, Benjamin Haibe-Kains, W. Fraser Symmans, Nicolai Juul Birkbak

Source: BMC bioinformatics, 12
Li, Q, Eklund, A C, Birkbak, N J, Desmedt, C, Haibe-Kains, B, Sotiriou, C, Symmans, W F, Pusztai, L, Brunak, S, Richardson, A L & Szallasi, Z I 2011, ' Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response ', B M C Bioinformatics, vol. 12, no. 1, pp. 310 . https://doi.org/10.1186/1471-2105-12-310
BMC Bioinformatics, Vol 12, Iss 1, p 310 (2011)
BMC Bioinformatics

Subject Terms: Cancérologie, Adenocarcinoma -- drug therapy -- genetics, Antineoplastic Agents -- therapeutic use, Breast Neoplasms -- drug therapy -- genetics, Cohort Studies, Estrogen Receptor alpha -- metabolism, Female, Gene Expression Profiling, Humans, Lung Neoplasms -- drug therapy -- genetics, Neoadjuvant Therapy, Neoplasms -- drug therapy -- genetics, Ovarian Neoplasms -- drug therapy -- genetics, Prognosis, Receptor, erbB-2 -- metabolism, Tumor Markers, Biological -- analysis, SDG 3 - Good Health and Well-being, lcsh:Computer applications to medicine. Medical informatics, lcsh:R858-859.7, lcsh:Biology (General), lcsh:QH301-705.5, Biochemistry, Molecular Biology, Computer Science Applications, Applied Mathematics, Structural Biology, Cancer, medicine.disease, medicine, Breast cancer, Gene expression profiling, Lung cancer, Oncology, medicine.medical_specialty, Internal medicine, Biology, Bioinformatics, Adenocarcinoma, Stage (cooking), Neoadjuvant therapy, medicine.medical_treatment, DNA microarray, Research Article