Search Results - "Lowengrub JS"

1

3D Mathematical modeling of glioblastoma suggests that transdifferentiated vascular endothelial cells promote resistance to current standard-of-care therapy

Authors: Bota, DA, Yan, H, Romero-Lopez, M, Benitez, L, Di, K, Frieboes, H, Hughes, CCW, Lowengrub, JS

Source: JOURNAL OF CLINICAL ONCOLOGY, vol 35, iss 15_suppl
Bota, DA; Yan, H; Romero-Lopez, M; Benitez, L; Di, K; Frieboes, H; et al.(2017). 3D Mathematical modeling of glioblastoma suggests that transdifferentiated vascular endothelial cells promote resistance to current standard-of-care therapy.. JOURNAL OF CLINICAL ONCOLOGY, 35. doi: 10.1200/JCO.2017.35.15_suppl.e13535. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/01m6060m

Subject Terms: Clinical Sciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Cancer Research, Oncology, fungi, endocrine system

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https://escholarship.org/uc/item/01m6060m

2

Recapitulating the human tumor microenvironment: colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth

Authors: Romero-Lopez, M, Trinh, AL, Sobrino, A, Hatch, MMS, Keating, MT, Fimbres, C, Lewis, DE, Gershon, PD, Botvinick, EL, Digman, M, Lowengrub, JS, Hughes, CCW

Source: Romero-Lopez, M; Trinh, AL; Sobrino, A; Hatch, MMS; Keating, MT; Fimbres, C; et al.(2017). Recapitulating the human tumor microenvironment: Colon tumor-derived zxtracellular matrix promotes angiogenesis and tumor cell growth. BIOMATERIALS, 116, 118-129. doi: 10.1016/j.biomaterials.2016.11.034. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9bq4n172

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https://europepmc.org/articles/PMC5226635/

3

Energy Stable and Efficient Finite-Difference Nonlinear Multigrid Schemes for the Modified Phase Field Crystal Equation

Authors: Baskaran, A, Hu, Z, Lowengrub, JS, Wang, C, Wise, SM, Zhou, P

Source: Journal of Computational Physics, vol 250
Baskaran, A; Hu, Z; Lowengrub, JS; Wang, C; Wise, SM; & Zhou, P. (2013). Energy stable and efficient finite-difference nonlinear multigrid schemes for the modified phase field crystal equation. Journal of Computational Physics, 250, 270-292. doi: 10.1016/j.jcp.2013.04.024. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9ph571mh

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http://arxiv.org/abs/1208.2643

4

Electronic Resource

Nonlinear modelling of cancer: bridging the gap between cells and tumours.

Authors: Lowengrub, JS

Source: Nonlinearity; vol 23, iss 1, R1-R9; 0951-7715

Index Terms: Cancer, 2.1 Biological and endogenous factors, General Mathematics, Applied Mathematics, article

URL: https://escholarship.org/uc/item/5v18w6jg
https://escholarship.org/

5

Academic Journal

A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease.

Authors: Hachey SJ; Irvine Department of Molecular Biology and Biochemistry, University of California, Irvine, California., Sobrino A; Irvine Department of Molecular Biology and Biochemistry, University of California, Irvine, California., Lee JG; Irvine School of Medicine, University of California, Irvine, California., Jafari MD; Department of Surgery, Weill Cornell Medicine, New York, New York., Klempner SJ; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Puttock EJ; Irvine Department of Mathematics, University of California, Irvine, California., Edwards RA; Irvine School of Medicine, University of California, Irvine, California., Lowengrub JS; Irvine Department of Mathematics, University of California, Irvine, California., Waterman ML; Irvine Department of Microbiology and Molecular Genetics, University of California, Irvine, California., Zell JA; Irvine School of Medicine, University of California, Irvine, California., Hughes CCW; Irvine Department of Molecular Biology and Biochemistry, University of California, Irvine, California; Irvine Department of Biomedical Engineering, University of California, Irvine, California. Electronic address: cchughes@uci.edu.

Source: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2022 Dec 05. Date of Electronic Publication: 2022 Dec 05.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101280339 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1810 (Electronic) Linking ISSN: 18781810 NLM ISO Abbreviation: Transl Res Subsets: MEDLINE

6

Academic Journal

Modelling glioma progression, mass effect and intracranial pressure in patient anatomy.

Authors: Lipková J; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Menze B; Department of Informatics, Technical University of Munich, Munich, Germany.; Department of Quantitative Biomedicine, University of Zürich, Zürich, Switzerland.; Department of Neuroradiology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Wiestler B; Department of Neuroradiology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Koumoutsakos P; Computational Science and Engineering Lab, ETH Zürich, Zürich, Switzerland.; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA., Lowengrub JS; Department of Mathematics, University of California, Irvine, CA, USA.; Department of Biomedical Engineering, University of California, Irvine, CA, USA.; Center for Complex Biological Systems, Chao Family Comprehensive Cancer Center, University of California, Irvine, CA, USA.

Source: Journal of the Royal Society, Interface [J R Soc Interface] 2022 Mar; Vol. 19 (188), pp. 20210922. Date of Electronic Publication: 2022 Mar 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Royal Society Country of Publication: England NLM ID: 101217269 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-5662 (Electronic) Linking ISSN: 17425662 NLM ISO Abbreviation: J R Soc Interface Subsets: MEDLINE

MeSH Terms: Glioma*/pathology , Intracranial Hypertension*/diagnosis , Intracranial Hypertension*/etiology, Brain ; Head ; Humans ; Intracranial Pressure

7

Academic Journal

Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth.

Authors: Yan H; Department of Mathematics, University of California, Irvine, Irvine, CA, 92697, USA., Konstorum A; Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, CT, 06030, USA., Lowengrub JS; Department of Mathematics, Department of Biomedical Engineering, Center for Complex Biological Systems, and Chao Comprehensive Cancer Center, University of California, Irvine, Irvine, CA, 92697, USA. lowengrb@math.uci.edu.

Source: Bulletin of mathematical biology [Bull Math Biol] 2018 May; Vol. 80 (5), pp. 1404-1433. Date of Electronic Publication: 2017 Jul 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 0401404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9602 (Electronic) Linking ISSN: 00928240 NLM ISO Abbreviation: Bull Math Biol Subsets: MEDLINE

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8

Academic Journal

Effect of feedback regulation on stem cell fractions in tissues and tumors: Understanding chemoresistance in cancer.

Authors: Weiss LD; Department of Mathematics, University of California Irvine, Irvine, CA 92697, United States., van den Driessche P; Department of Mathematics and Statistics, University of Victoria, Victoria, BC V8W 2Y2, Canada., Lowengrub JS; Department of Mathematics, University of California Irvine, Irvine, CA 92697, United States., Wodarz D; Department of Mathematics, University of California Irvine, Irvine, CA 92697, United States; Department of Population Health and Disease Prevention, Program in Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, CA 92697, United States., Komarova NL; Department of Mathematics, University of California Irvine, Irvine, CA 92697, United States. Electronic address: komarova@uci.edu.

Source: Journal of theoretical biology [J Theor Biol] 2021 Jan 21; Vol. 509, pp. 110499. Date of Electronic Publication: 2020 Oct 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0376342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8541 (Electronic) Linking ISSN: 00225193 NLM ISO Abbreviation: J Theor Biol Subsets: MEDLINE

MeSH Terms: Drug Resistance, Neoplasm* , Neoplasms*, Animals ; Cell Differentiation ; Cell Line, Tumor ; Feedback ; Mice ; Neoplastic Stem Cells

9

Academic Journal

Optimal experimental design for mathematical models of haematopoiesis.

Authors: Lomeli LM; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA., Iniguez A; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA., Tata P; Division of Hematology/Oncology, University of California Irvine, Irvine, CA, USA., Jena N; Division of Hematology/Oncology, University of California Irvine, Irvine, CA, USA., Liu ZY; Division of Hematology/Oncology, University of California Irvine, Irvine, CA, USA., Van Etten R; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA.; Division of Hematology/Oncology, University of California Irvine, Irvine, CA, USA.; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.; Center for Cancer Systems Biology, University of California Irvine, Irvine, CA, USA.; Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Lander AD; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA.; Center for Cancer Systems Biology, University of California Irvine, Irvine, CA, USA.; Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA., Shahbaba B; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA.; Center for Cancer Systems Biology, University of California Irvine, Irvine, CA, USA.; Department of Statistics, University of California Irvine, Irvine, CA, USA., Lowengrub JS; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA.; Center for Cancer Systems Biology, University of California Irvine, Irvine, CA, USA.; Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA.; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA.; Department of Mathematics, University of California Irvine, Irvine, CA, USA., Minin VN; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA.; Center for Cancer Systems Biology, University of California Irvine, Irvine, CA, USA.; Department of Statistics, University of California Irvine, Irvine, CA, USA.

Source: Journal of the Royal Society, Interface [J R Soc Interface] 2021 Jan; Vol. 18 (174), pp. 20200729. Date of Electronic Publication: 2021 Jan 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Royal Society Country of Publication: England NLM ID: 101217269 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-5662 (Electronic) Linking ISSN: 17425662 NLM ISO Abbreviation: J R Soc Interface Subsets: MEDLINE

MeSH Terms: Hematopoiesis* , Research Design*, Animals ; Bayes Theorem ; Cell Division ; Models, Biological

10

Academic Journal

Feedback, Lineages and Self-Organizing Morphogenesis.

Authors: Kunche S; Department of Biomedical Engineering, University of California, Irvine, Irvine, California, United States of America.; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, United States of America., Yan H; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, United States of America.; Department of Mathematics, University of California, Irvine, Irvine, California, United States of America., Calof AL; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, United States of America.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, United States of America.; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California, United States of America., Lowengrub JS; Department of Biomedical Engineering, University of California, Irvine, Irvine, California, United States of America.; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, United States of America.; Department of Mathematics, University of California, Irvine, Irvine, California, United States of America., Lander AD; Department of Biomedical Engineering, University of California, Irvine, Irvine, California, United States of America.; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, United States of America.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, United States of America.

Source: PLoS computational biology [PLoS Comput Biol] 2016 Mar 18; Vol. 12 (3), pp. e1004814. Date of Electronic Publication: 2016 Mar 18 (Print Publication: 2016).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

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11

Academic Journal

Tumor growth and calcification in evolving microenvironmental geometries.

Authors: Chen Y; Department of Mathematics, Duke University, Durham, USA. Electronic address: yingc@math.duke.edu., Lowengrub JS; Department of Mathematics, Department of Biomedical Engineering, Center for Complex Biological Systems, University of California, Irvine, USA. Electronic address: lowengrb@math.uci.edu.

Source: Journal of theoretical biology [J Theor Biol] 2019 Feb 21; Vol. 463, pp. 138-154. Date of Electronic Publication: 2018 Dec 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0376342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8541 (Electronic) Linking ISSN: 00225193 NLM ISO Abbreviation: J Theor Biol Subsets: MEDLINE

MeSH Terms: Calcinosis* , Models, Biological*, Neoplasms/*pathology, Basement Membrane/metabolism ; Basement Membrane/ultrastructure ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Ductal, Breast/ultrastructure ; Cell Adhesion ; Computer Simulation ; Humans

12

Academic Journal

A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma.

Authors: Koay EJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ekoay@mdanderson.org., Lee Y; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cristini V; Center for Precision Biomedicine, The University of Texas Health Science Center, Houston, Texas.; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas.; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lowengrub JS; Department of Mathematics, University of California, Irvine, California.; Department of Biomedical Engineering, University of California, Irvine, California.; Chao Family Comprehensive Cancer Center, University of California, Irvine, California.; Center for Complex Biological Systems, University of California, Irvine, California., Kang Y; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lucas FAS; Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hobbs BP; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ye R; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Elganainy D; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Almahariq M; Deparment of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas., Amer AM; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chatterjee D; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yan H; Department of Mathematics, University of California, Irvine, California., Park PC; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Rios Perez MV; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Li D; Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Garg N; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Reiss KA; Department of Medical Oncology, The University of Pennsylvania Abramson Cancer Center, Philadelphia, Pennsylvania., Yu S; Department of Internal Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Chauhan A; Department of Radiology, The University of Pennsylvania, Philadelphia, Pennsylvania., Zaid M; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Nikzad N; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wolff RA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Javle M; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Varadhachary GR; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shroff RT; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Das P; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lee JE; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ferrari M; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas., Maitra A; Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Taniguchi CM; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kim MP; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Crane CH; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Katz MH; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang H; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bhosale P; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tamm EP; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Fleming JB; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Dec 01; Vol. 24 (23), pp. 5883-5894. Date of Electronic Publication: 2018 Aug 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

13

Academic Journal

Modeling solvent evaporation during thin film formation in phase separating polymer mixtures.

Authors: Cummings J; Department of Mathematics, The University of Tennessee, Knoxville, TN-37996, USA. swise1@utk.edu., Lowengrub JS, Sumpter BG, Wise SM, Kumar R

Source: Soft matter [Soft Matter] 2018 Mar 07; Vol. 14 (10), pp. 1833-1846.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101295070 Publication Model: Print Cited Medium: Internet ISSN: 1744-6848 (Electronic) Linking ISSN: 1744683X NLM ISO Abbreviation: Soft Matter Subsets: PubMed not MEDLINE

14

Academic Journal

Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model.

Authors: Konstorum A; Center for Quantitative Medicine, UConn Health, Farmington, CT, USA. Electronic address: konstorum@uchc.edu., Lowengrub JS; Department of Mathematics, University of California, Irvine, CA, USA; Center for Complex Biological Systems, University of California, Irvine, CA, USA; Department of Biomedical Engineering, University of California, Irvine, CA, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, USA. Electronic address: lowengrb@math.uci.edu.

Source: Journal of theoretical biology [J Theor Biol] 2018 Feb 14; Vol. 439, pp. 86-99. Date of Electronic Publication: 2017 Dec 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0376342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8541 (Electronic) Linking ISSN: 00225193 NLM ISO Abbreviation: J Theor Biol Subsets: MEDLINE

MeSH Terms: Models, Biological* , Paracrine Communication* , Tumor Microenvironment*, Hepatocyte Growth Factor/*metabolism , Proto-Oncogene Proteins c-met/*metabolism, Animals ; Cancer-Associated Fibroblasts/metabolism ; Cell Proliferation ; Humans ; Neoplasm Invasiveness ; Spatio-Temporal Analysis

15

Academic Journal

Multiscale modeling of glioblastoma.

Authors: Yan H; Department of Mathematics, University of California, Irvine, USA., Romero-López M; Department of Biomedical Engineering, University of California, Irvine, USA., Benitez LI; Department of Molecular Biology and Biochemistry, University of California, Irvine, USA., Di K; Department of Neurology, University of California, Irvine, USA., Frieboes HB; James Graham Brown Cancer Center, University of Louisville, Louisville, USA.; Department of Bioengineering, University of Louisville, Louisville, USA., Hughes CCW; Department of Biomedical Engineering, University of California, Irvine, USA.; Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.; Chao Comprehensive Cancer Center, University of California, Irvine, USA.; Center for Complex Biological Systems, University of California, Irvine, USA., Bota DA; Department of Neurology, University of California, Irvine, USA.; Chao Comprehensive Cancer Center, University of California, Irvine, USA.; Department of Neurological Surgery, University of California, Irvine, USA., Lowengrub JS; Department of Mathematics, University of California, Irvine, USA.; Department of Biomedical Engineering, University of California, Irvine, USA.; Chao Comprehensive Cancer Center, University of California, Irvine, USA.; Center for Complex Biological Systems, University of California, Irvine, USA.

Source: Translational cancer research [Transl Cancer Res] 2018 Feb; Vol. 7 (Suppl 1), pp. S96-S98.

Publication Type: Journal Article

Journal Info: Publisher: Pioneer Bioscience Publishing Company Country of Publication: China NLM ID: 101585958 Publication Model: Print Cited Medium: Print ISSN: 2218-676X (Print) Linking ISSN: 2218676X NLM ISO Abbreviation: Transl Cancer Res Subsets: PubMed not MEDLINE

16

Academic Journal

3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy.

Authors: Yan H; Department of Mathematics, University of California, Irvine, California., Romero-López M; Department of Biomedical Engineering, University of California, Irvine, California., Benitez LI; Department of Molecular Biology and Biochemistry, University of California, Irvine, California., Di K; Chao Comprehensive Cancer Center, University of California, Irvine, California.; Department of Neurological Surgery, University of California, Irvine, California., Frieboes HB; James Graham Brown Cancer Center, University of Louisville.; Department of Bioengineering, University of Louisville, Louisville, Kentucky., Hughes CCW; Department of Biomedical Engineering, University of California, Irvine, California.; Department of Molecular Biology and Biochemistry, University of California, Irvine, California.; Chao Comprehensive Cancer Center, University of California, Irvine, California.; Center for Complex Biological Systems, University of California, Irvine, California., Bota DA; Chao Comprehensive Cancer Center, University of California, Irvine, California.; Department of Neurological Surgery, University of California, Irvine, California.; Department of Neurology, University of California, Irvine, California., Lowengrub JS; Department of Mathematics, University of California, Irvine, California. lowengrb@math.uci.edu.; Department of Biomedical Engineering, University of California, Irvine, California.; Chao Comprehensive Cancer Center, University of California, Irvine, California.; Center for Complex Biological Systems, University of California, Irvine, California.

Source: Cancer research [Cancer Res] 2017 Aug 01; Vol. 77 (15), pp. 4171-4184. Date of Electronic Publication: 2017 May 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

MeSH Terms: Models, Theoretical*, Brain Neoplasms/*pathology , Endothelial Cells/*pathology , Glioblastoma/*pathology , Neoplastic Stem Cells/*pathology, Cell Transdifferentiation/physiology ; Humans

17

Academic Journal

Selection in spatial stochastic models of cancer: migration as a key modulator of fitness.

Authors: Thalhauser CJ; Department of Mathematics, University of California Irvine, Irvine, California, USA., Lowengrub JS, Stupack D, Komarova NL

Source: Biology direct [Biol Direct] 2010 Apr 20; Vol. 5, pp. 21. Date of Electronic Publication: 2010 Apr 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE

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18

Academic Journal

Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness.

Authors: Yan H, Romero-Lopez M, Frieboes HB, Hughes CC, Lowengrub JS

Source: IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2017 Mar; Vol. 64 (3), pp. 538-548. Date of Electronic Publication: 2016 Oct 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

Journal Info: Publisher: Institute Of Electrical And Electronics Engineers Country of Publication: United States NLM ID: 0012737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-2531 (Electronic) Linking ISSN: 00189294 NLM ISO Abbreviation: IEEE Trans Biomed Eng Subsets: MEDLINE

19

Academic Journal

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.

Authors: Romero-López M; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Trinh AL; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Sobrino A; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Hatch MM; Department of Molecular Biology and Biochemistry, School of Biological Sciences, UC Irvine, USA., Keating MT; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Fimbres C; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Lewis DE; Department of Molecular Biology and Biochemistry, School of Biological Sciences, UC Irvine, USA., Gershon PD; Department of Molecular Biology and Biochemistry, School of Biological Sciences, UC Irvine, USA., Botvinick EL; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, UC Irvine, USA., Digman M; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA., Lowengrub JS; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA; Department of Mathematics, School of Physical Sciences, UC Irvine, USA., Hughes CC; Department of Biomedical Engineering, The Henry Samueli School of Engineering, UC Irvine, USA; Department of Molecular Biology and Biochemistry, School of Biological Sciences, UC Irvine, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, UC Irvine, USA. Electronic address: cchughes@uci.edu.

Source: Biomaterials [Biomaterials] 2017 Feb; Vol. 116, pp. 118-129. Date of Electronic Publication: 2016 Nov 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

MeSH Terms: Tumor Microenvironment*, Colonic Neoplasms/*pathology , Colonic Neoplasms/*physiopathology , Extracellular Matrix/*metabolism , Extracellular Matrix/*pathology , Neovascularization, Pathologic/*pathology , Neovascularization, Pathologic/*physiopathology, Cell Proliferation ; Colonic Neoplasms/blood supply ; Humans ; Tumor Cells, Cultured

20

Academic Journal

Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching.

Authors: Cristini V; The University of Texas MD Anderson Cancer Center, School of Health Information Sciences, University of Texas Health Science Center, Houston, TX 77030, USA., Li X, Lowengrub JS, Wise SM

Source: Journal of mathematical biology [J Math Biol] 2009 Apr; Vol. 58 (4-5), pp. 723-63. Date of Electronic Publication: 2008 Sep 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7502105 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0303-6812 (Print) Linking ISSN: 03036812 NLM ISO Abbreviation: J Math Biol Subsets: MEDLINE

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