Showing 1 - 20 results of 57 for search '"Liver Neoplasms genetics"', query time: 1.21s Refine Results

Contributors: Groningen Institute for Organ Transplantation (GIOT)

Source: American Journal of Surgical Pathology, 45(4), 477-487. LIPPINCOTT WILLIAMS & WILKINS
The American journal of surgical pathology, vol. 45, no. 4, pp. 477-487

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Contributors: Dentro, SC, Wedge, DC, Yang, T-P, Organismal and Evolutionary Biology Research Programme, Institute of Biotechnology, Bioinformatics, Department of Computer Science

Source: Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Cmero, M, Yuan, K, Ong, C S, Schröder, J, Adams, D J, Anur, P, Beroukhim, R, Boutros, P C, Bowtell, D D L, Campbell, P J, Cao, S, Christie, E L, Cun, Y, Dawson, K J, Demeulemeester, J, Dentro, S C, Deshwar, A G, Donmez, N, Drews, R M, Eils, R, Fan, Y, Fittall, M W, Garsed, D W, Gerstung, M, Getz, G, Gonzalez, S, Ha, G, Haase, K, Imielinski, M, Jerman, L, Ji, Y, Jolly, C, Kleinheinz, K, Lee, J, Lee-Six, H, Leshchiner, I, Livitz, D, Malikic, S, Martincorena, I, Mitchell, T J, Morris, Q D, Mustonen, V, Oesper, L, Peifer, M, Peto, M, Raphael, B J, Rosebrock, D, Rubanova, Y, Sahinalp, S C, Salcedo, A, Schlesner, M, Schumacher, S E, Sengupta, S, Shi, R, Shin, S J, Spellman, P T, Spiro, O, Stein, L D, Tarabichi, M, Van Loo, P, Vembu, S, Vázquez-García, I, Wang, W, Wedge, D C, Wheeler, D A, Wintersinger, J A, Yang, T-P, Yao, X, Yu, K, Zhu, H, Corcoran, N M, Papenfuss, T, Hovens, C M, Markowetz, F & Macintyre, G 2020, ' Inferring structural variant cancer cell fraction ', Nature Communications, vol. 11, no. 1 .
essn: 2041-1723
nlmid: 101528555
Nature Communications

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Contributors: Graduate School, Medical Oncology, Urology, Chemical Biology

Source: Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Nature communications, 10(1):5251. Nature Publishing Group
Nature Communications, 10:5251. Nature Publishing Group
Nature Communications
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, 10(1):5251. Nature Publishing Group

Subject Terms: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Computational biology, Prostate cancer, medicine.disease, medicine, Microsatellite instability, Genotype, Tandem exon duplication, Whole genome sequencing, Tumor progression, Biology, Castration resistant, Prostate, medicine.anatomical_structure, lcsh:Science, lcsh:Q, Lymph Nodes, Humans, Bone Neoplasms, Liver Neoplasms, Soft Tissue Neoplasms, Prostatic Neoplasms, Neoplasm Metastasis, Cyclin-Dependent Kinases, Oncogene Proteins, Fusion, BRCA2 Protein, Receptors, Androgen, Male, Microsatellite Instability, Enhancer Elements, Genetic, DNA Copy Number Variations, Recombinational DNA Repair, Castration-Resistant, Whole Genome Sequencing, Chromatin Immunoprecipitation Sequencing, Biotechnology, Genetics, Cancer, Prostate Cancer, Urologic Diseases, Human Genome, SDG 3 - Good Health and Well-being, Article, Genetics research, Science, Physics and Astronomy(all), Chemistry(all), Biochemistry, Genetics and Molecular Biology(all), Journal Article, BRCA2 Protein/genetics, Bone Neoplasms/genetics, Cyclin-Dependent Kinases/genetics, Genetic/genetics, Liver Neoplasms/genetics, Fusion/genetics, Prostatic Neoplasms/genetics, Castration-Resistant/classification, Androgen/genetics, Recombinational DNA Repair/genetics, Soft Tissue Neoplasms/genetics, Enhancer Elements, Genetic/genetics, Oncogene Proteins, Fusion/genetics, Prostatic Neoplasms, Castration-Resistant/classification, Receptors, Androgen/genetics, Biochemistry, Genetics and Molecular Biology(all)

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Contributors: Universitätsklinikum Tübingen - University Hospital of Tübingen, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe labellisée Ligue contre le Cancer, National Cancer Institute [Bethesda] (NCI-NIH), National Institutes of Health [Bethesda] (NIH), Universität Zürich [Zürich] = University of Zurich (UZH), Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), RWTH Aachen University, Vienna Biocenter - VBC [Austria], University of Tübingen, Heidelberg University Hospital [Heidelberg], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), German Cancer Consortium [Heidelberg] (DKTK), This work was supported by the ERC Consolidator Grant ‘CholangioConcept’ (to L.Z.), the German Research Foundation (DFG): grants FOR2314, SFB685, SFB/TR209 and the Gottfried Wilhelm Leibniz Program (to L.Z.). Further funding was provided by the German Ministry for Education and Research (BMBF) (e:Med/Multiscale HCC), the German Universities Excellence Initiative (third funding line: ‘future concept’), the German Center for Translational Cancer Research (DKTK), the German-Israeli Cooperation in Cancer Research (DKFZ-MOST) (to L.Z.) and the Intramural Research Program of the Centre for Cancer Research, National Cancer Institute, National Institutes of Health (to X.W.W.). The group of O.B. is supported by grants from ANR-BMFT, Fondation ARC pour la recherche sur le Cancer, INSERM, and the National Cancer Institute of the National Institutes of Health under Award Number R01CA136533. O.B. is a CNRS fellow., We thank E. Rist, P. Schiemann, C. Fellmeth, C.-J. Hsieh, D. Heide and J. Hetzer for technical help or assistance. We thank A. Weber for providing TLR2 and TLR4 knockout mice and W. S. Alexander and The Walter and Eliza Hall Institute of Medical Research for providing Mlklfl/fl mice. The Cas9n–p19Arf sgRNA vector was provided by W. Xue. We thank the c.ATG facility of Tuebingen University and CeGaT Tuebingen for exome sequencing and data analysis., Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), University of Zurich, Zender, Lars

Source: Nature
Nature, Nature Publishing Group, 2018, 562 (7725), pp.69-75. ⟨10.1038/s41586-018-0519-y⟩

Subject Terms: Cancer epigenetics, Cancer microenvironment, MESH: Animals, MESH: Apoptosis*/genetics, MESH: Cytokines/metabolism, MESH: DNA Transposable Elements/genetics, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Disease Models, Animal, MESH: Epigenesis, Genetic/genetics, MESH: Female, MESH: Gene Expression Profiling, MESH: Genes, myc, MESH: Genes, ras, MESH: Carcinogenesis/genetics, MESH: Hepatocytes/metabolism, MESH: Hepatocytes/pathology, MESH: Humans, MESH: Liver Neoplasms/genetics, MESH: Liver Neoplasms/pathology, MESH: Male, MESH: Mice, MESH: Mosaicism, MESH: Necrosis*/genetics, MESH: Proto-Oncogene Proteins c-akt/genetics, MESH: Carcinoma, Hepatocellular/genetics, MESH: T-Box Domain Proteins/genetics, MESH: T-Box Domain Proteins/metabolism, MESH: Transcription Factors/genetics, MESH: Transcription Factors/metabolism, MESH: Tumor Microenvironment, MESH: Carcinoma, Hepatocellular/pathology, MESH: Cell Differentiation, MESH: Cell Lineage*/genetics, MESH: Cholangiocarcinoma/genetics, MESH: Cholangiocarcinoma/pathology, MESH: Cyclin-Dependent Kinase Inhibitor p16/deficiency, [SDV.CAN]Life Sciences [q-bio]/Cancer, Multidisciplinary, Hepatic stellate cell, Cellular differentiation, Cancer research, Liver cancer, medicine.disease, medicine, Necroptosis, Biology, Context (language use), Epigenome, Tumor microenvironment, digestive system diseases, Article, 570 Life sciences, biology, 610 Medicine & health, 10239 Institute of Laboratory Animal Science, 1000 Multidisciplinary

File Description: Seehawer_2018_NATURE_Necroptosis_liver.pdf - application/pdf


Source: BMC Cancer
Mogensen, M B, Rossing, M, Østrup, O, Larsen, P N, Heiberg Engel, P J, Jørgensen, L N, Hogdall, E V, Eriksen, J, Ibsen, P, Jess, P, Grauslund, M, Nielsen, H J, Nielsen, F C, Vainer, B & Osterlind, K 2018, ' Genomic alterations accompanying tumour evolution in colorectal cancer : tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing ', BMC Cancer, vol. 18, 752 .
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)

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Contributors: Grupo de Gastrohepatologia [Medellin, Colombia], Universidad de Antioquia = University of Antioquia [Medellín, Colombia], Departamento de Patologia [Medellin, Colombia], Facultad de Psicología, Valencia, Hospital Pablo Tobón Uribe [Medellín, Colombie], Fundacion Santa Fe de Bogota [Colombia], International Prevention Research Institute (IPRI), Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was funded by Departamento Nacional de Ciencia, Innovación y Tecnologia Colciencias (Grant 111540820471) and Proyecto de Sostenibilidad, Vicerrectoría de Investigación, Universidad de Antioquia., We thank Dr. Anne Lise Haenni from the Institut Jacques Monod for critical reading of the manuscript and Dr. Andres Arias from Universidad de Antioquia for discussion of the results. We also thank Ghyslaine Martel from International Agency for Research on Cancer (IARC) and Beatriz Vieco from Departamento de Patología, Universidad de Antioquia, for technical assistance.

Source: Annals of hepatology : official journal of the Mexican Association of Hepatology
Annals of hepatology : official journal of the Mexican Association of Hepatology, Elsevier, 2015, 14 (1), pp.64-74. ⟨10.1016/S1665-2681(19)30802-6⟩
Annals of Hepatology, Vol 14, Iss 1, Pp 64-74 (2015)


Contributors: Laboratoire des Hépatites Virales [Casablanca, Maroc] (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), CHU Ibn Rochd [Casablanca], Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by The European Commission under the Health Cooperation Work Program of the 7th Framework Program for the Research and Technological Development, HepaCute Project (Grant Agreement No. 260844)., European Project: 260844,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,HEPACUTE(2010), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]

Source: Infection, Genetics and Evolution
Infection, Genetics and Evolution, Elsevier, 2014, 21, pp.179-183. ⟨10.1016/j.meegid.2013.11.005⟩


Contributors: Laboratoire des Hépatites Virales [Casablanca, Maroc] (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université Mohammed V, CHU Ibn-Sina [Rabat] (CHUIS), Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by Pasteur Institute of Morocco and the Pasteur Institutes International Network (RIIP)., The authors would like to acknowledge all patients for their participation in this study., Université Mohammed V de Rabat [Agdal] (UM5)

Source: Cancer Epidemiology
Cancer Epidemiology, Elsevier, 2012, 36 (5), pp.e300-e305. ⟨10.1016/j.canep.2012.05.011⟩


Contributors: Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Département de pathologie [Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Department of Anatomic Pathology, Chang Gung Memorial Hospital [Taipei] (CGMH), Service de Pathologie Clinique, Université de Lausanne = University of Lausanne (UNIL)-Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV)-Institut Universitaire de Pathologie, Service d'immunologie biologique, Centre de Biologie et de Pathologie, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL)-Hôpital Renée Sabran [CHU - HCL], Hospices Civils de Lyon (HCL), Département de biologie et pathologie médicales [Gustave Roussy], Institut Gustave Roussy (IGR), Gvh et Gvl : Physiopathologie Chez l'Homme et Chez l'Animal, Incidence et Role Therapeutique, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'anatomo-pathologie [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Immunologie, dermatologie, oncologie, Oncodermatologie, immunologie et cellules souches cutanées (IDO (U976 / UMR_S 976)), Service hématologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Department of histopathology, University College Hospital, (le programme) Cartes d'identité des tumeurs (CIT), Ligue Nationales Contre le Cancer (LNCC), This work is part of the Carte d'Identité des Tumeurs (CIT) program ( from the Ligue Nationale Contre le Cancer and of the Tenomic project inserm-00730464, version 1 - 10 Sep 2012 supported by a Programme Hospitalier de Recherche Clinique and the Institut National du Cancer (INCa). This work was supported by the Institut National de la Santé et de la Recherche Médicale (INSERM), the Institut National du Cancer (INCa), the Plan cancer of the Belgian government, and the Association pour la Recherche Thérapeutique, Génétique et Immunologique dans les Lymphomes (ARTGIL). M.T. was supported by the Fondation pour la Recherche Médicale (DEQ 2010/0318253), Université de Lausanne (UNIL)-Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV)-Institut Universitaire de Pathologie, Université Paris Diderot - Paris 7 (UPD7)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris]

Source: Blood
Blood, 2012, 119 (24), pp.5795-806. ⟨10.1182/blood-2011-12-396150⟩
Blood, American Society of Hematology, 2012, 119 (24), pp.5795-806. ⟨10.1182/blood-2011-12-396150⟩
Blood, vol. 119, no. 24, pp. 5795-5806

Subject Terms: MESH: Aged, MESH: Gene Expression Regulation, Neoplastic, MESH: Genes, Neoplasm, MESH: Humans, MESH: Intracellular Signaling Peptides and Proteins, MESH: Isochromosomes, MESH: Liver Neoplasms, MESH: Lymphoma, T-Cell, MESH: Male, MESH: Membrane Proteins, MESH: Middle Aged, MESH: Base Sequence, MESH: Molecular Sequence Data, MESH: Molecular Targeted Therapy, MESH: Protein-Tyrosine Kinases, MESH: Receptors, Antigen, T-Cell, alpha-beta, MESH: Receptors, Antigen, T-Cell, gamma-delta, MESH: Splenic Neoplasms, MESH: Tumor Markers, Biological, MESH: Young Adult, MESH: Adult, MESH: Cell Lineage, MESH: Chromosome Aberrations, MESH: Cluster Analysis, MESH: Crystallins, MESH: Drug Resistance, Neoplasm, MESH: Female, MESH: Gene Expression Profiling, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Cell Biology, Hematology, Immunology, Biochemistry, CpG site, Tyrosine kinase, Biology, Hepatosplenic T-cell lymphoma, medicine.disease, medicine, Syk, Gene expression profiling, T-cell lymphoma, Cancer research, Lymphoma, T-cell receptor, Article, Adult, Aged, Base Sequence, Cell Lineage/genetics, Chromosome Aberrations, Cluster Analysis, Crystallins/metabolism, Drug Resistance, Neoplasm/genetics, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genes, Neoplasm/genetics, Humans, Intracellular Signaling Peptides and Proteins/antagonists & inhibitors, Intracellular Signaling Peptides and Proteins/metabolism, Isochromosomes/genetics, Liver Neoplasms/drug therapy, Liver Neoplasms/genetics, Lymphoma, T-Cell/drug therapy, Lymphoma, T-Cell/genetics, Male, Membrane Proteins/metabolism, Middle Aged, Molecular Sequence Data, Molecular Targeted Therapy, Protein-Tyrosine Kinases/antagonists & inhibitors, Protein-Tyrosine Kinases/metabolism, Receptors, Antigen, T-Cell, alpha-beta/genetics, Receptors, Antigen, T-Cell, gamma-delta/genetics, Splenic Neoplasms/drug therapy, Splenic Neoplasms/genetics, Tumor Markers, Biological/genetics, Tumor Markers, Biological/metabolism, Young Adult

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Source: PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e20090 (2011)