Authors: Rouco, Raquel, Bompadre, Olimpia, Rauseo, Antonella, Fazio, Olivier, Peraldi, Rodrigue, Thorel, Fabrizio, Andrey, Guillaume
Source:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, Vol. 12, No 1 (2021) P. 7235
Nature Communications
Subject Terms: Science, ddc:590, ddc:576.5, Acetylation, Animals, Chromatin / chemistry, Chromatin / metabolism, Connective Tissue / growth & development, Connective Tissue / metabolism, Embryo, Mammalian, Enhancer Elements, Genetic / genetics, Epigenesis, Genetic, Gene Expression Regulation, Developmental, Hindlimb / cytology, Hindlimb / embryology, Hindlimb / metabolism, Limb Buds / cytology, Limb Buds / embryology, Limb Buds / metabolism, Mice, Models, Genetic, Paired Box Transcription Factors / genetics, Paired Box Transcription Factors / metabolism, Sequence Deletion, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary, Article, Developmental biology, Development, Gene regulation, RNA sequencing, Genetic models
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https://doaj.org/article/0b815c21fe024b74b873bddc50a6f53e
Authors: Judith Mazariegos, Sheila Cárcel, Thileepan Sekaran, Kerstin Bartscherer, Rafael Romero, Jordi Ginés, Susanna Fraguas, Coral Vivancos, Francesc Cebrià, Ma Dolores Molina
Contributors: Hubrecht Institute for Developmental Biology and Stem Cell Research
Source:
Developmental Biology, 476, 53-67. Academic Press
Dipòsit Digital de la UB
Universidad de Barcelona
Subject Terms: Cell Biology, Developmental Biology, Molecular Biology, Cell biology, Chromatin, Schmidtea mediterranea, biology.organism_classification, biology, Cellular differentiation, Cell type, Planarian, Developmental biology, Stem cell, CREB-binding protein, biology.protein, Animals, CREB-Binding Protein/genetics, Cell Differentiation/genetics, Cell Proliferation, Chromatin/metabolism, Histones/metabolism, Planarians/genetics, Regeneration/genetics, Stem Cells/cytology, Transcription Factors/metabolism, Planària (Gènere), Regeneració (Biologia), Cèl·lules mare, Planaria (Genus), Regeneration (Biology), Stem cells
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https://doi.org/10.1016/j.ydbio.2021.02.008
Authors: Olan, I., Parry, A. J., Schoenfelder, S., Narita, M., Ito, Y., Chan, A. S. L., Slater, G. S. C., Bihary, D., Bando, M., Shirahige, K., Kimura, Hiroshi, Samarajiwa, S. A., Fraser, P.
Source:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Subject Terms: Science, biological phenomena, cell phenomena, and immunity, CCCTC-Binding Factor/metabolism, Cell Cycle Proteins/*metabolism, Cell Differentiation/genetics, Cell Line, Cellular Senescence/*genetics, Chromatin/*metabolism, Chromosomal Proteins, Non-Histone/*metabolism, Enhancer Elements, Genetic/genetics, Gene Expression Regulation, Genetic Loci, Genome, Humans, Interleukin-1/genetics, Macrophages/cytology, Promoter Regions, Genetic, Protein Binding/drug effects, Transcription, Genetic, Tumor Necrosis Factor-alpha/pharmacology, ras Proteins/metabolism, Article, 631/1647/2210/2211, 631/80/509, 631/114/2114, 631/208/200, 631/337/100/101, 38, 38/32, 45/15, 45/23, 45/77, 45/88, 45/91, Chromatin analysis, Senescence, Gene regulatory networks, Gene regulation, Chromatin structure, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Gene, Chromatin, Cell biology, Cell fate determination, Regulation of gene expression, Transcription (biology), Tissue homeostasis, Cohesin, Biology
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https://doaj.org/article/cfcc6e6ce1f94a00978bd38e7e46977b
Authors: Sakamoto, Y., Sato, M., Sato, Y., Harada, A., Suzuki, T., Goto, C., Tamura, K., Toyooka, K., Kimura, Hiroshi, Ohkawa, Y., Hara-Nishimura, I., Takagi, S., Matsunaga, S.
Source:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Subject Terms: Science, genetic structures, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Biology, Arabidopsis, biology.organism_classification, Regulation of gene expression, Locus (genetics), Lamina, Chromatin, Gene, Nuclear lamina, Cell biology, Gene expression, Article, Developmental biology, Plant sciences, lcsh:Science, lcsh:Q, Arabidopsis/genetics, Arabidopsis Proteins/genetics/metabolism, Cell Nucleus/metabolism, Chromatin/metabolism, Copper/*metabolism, Gene Expression Regulation, Plant, In Situ Hybridization, Fluorescence, Mutation/genetics, Nuclear Lamina/genetics/metabolism/ultrastructure, Nuclear Proteins/genetics/metabolism, Plant Proteins/genetics/metabolism, RNA-Seq
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https://doaj.org/article/c86f370d5995440ea4edd12a155f947b
Authors: Yasuyuki Ohkawa, Masaru Nakao, Tetsuya Handa, Shoko Sato, Hiroshi Kimura, Kazumitsu Maehara, Naoki Goto, Hitoshi Kurumizaka, Akihito Harada
Source: Nat Protoc. 15(No. 10):3334-3360
Subject Terms: Animals, Cell Line, Cell Line, Tumor, Chromatin/metabolism, Chromatin Immunoprecipitation/methods, Chromatin Immunoprecipitation Sequencing/*methods, Chromosome Mapping/*methods, DNA-Binding Proteins/*analysis, Epigenesis, Genetic/genetics, Epigenomics/methods, Gene Library, Genome, Genomics, High-Throughput Nucleotide Sequencing/methods, Histones/metabolism, Humans, Mice, Protein Processing, Post-Translational/genetics, Sequence Analysis, DNA/methods, Transcription Factors/metabolism, Transposases/metabolism, General Biochemistry, Genetics and Molecular Biology, Genomic library, Chromatin, Computational biology, Whole genome sequencing, Chemistry, Epigenomics, Transcription factor, Transcription (biology), Target protein, Chromatin immunoprecipitation
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http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100852388
Authors: Jonathan Lucien Stahl, Elena Favaro, Line Christoffersen, Claudia Guasch Boldú, Saara Hämälistö, Ben Loos, Marin Barisic, Johanna A. Joyce, Thomas Reinheckel, Bin Liu, Qing Yang, Marja Jäättelä
Source:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, vol. 11, no. 1, pp. 229
Hämälistö, S, Stahl, J L, Favaro, E, Yang, Q, Liu, B, Christoffersen, L, Loos, B, Guasch Boldú, C, Joyce, J A, Reinheckel, T, Barisic, M & Jäättelä, M 2020, ' Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation ', Nature Communications, vol. 11, no. 1, 229 . https://doi.org/10.1038/s41467-019-14009-0
Subject Terms: Science, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Lysosomal lumen, Mitosis, Histone H3, Cell biology, Programmed cell death, Cell division, Cytoplasm, Cathepsin B, Chromosome separation, Chemistry, Article, Chromosome segregation, Molecular biology, Animals, Cathepsin B/antagonists & inhibitors, Cathepsin B/genetics, Cathepsin B/metabolism, Cell Line, Cell Nucleus/genetics, Cell Nucleus/pathology, Chromatin/metabolism, Chromosome Segregation/genetics, Female, Gene Silencing, Histones/metabolism, Humans, Intracellular Membranes/metabolism, Lysosomes/enzymology, Lysosomes/metabolism, Metaphase, Mice, Mitosis/genetics, Permeability, Telomere/metabolism, lcsh:Science, lcsh:Q
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https://doaj.org/article/79e29c43ae8e4889bba0b9d7d4022b96
Authors: Ge, Xiangyu, Frank-Bertoncelj, Mojca, Klein, Kerstin, McGovern, Amanda, Kuret, Tadeja, Houtman, Miranda, Burja, Blaž, Micheroli, Raphael, Shi, Chenfu, Marks, Miriam, Filer, Andrew, Buckley, Christopher D, Orozco, Gisela, Distler, Oliver, Morris, Andrew P, Martin, Paul, Eyre, Stephen, Ospelt, Caroline
Contributors: University of Zurich, Ospelt, Caroline
Source:
Ge, X, Frank-Bertoncelj, M, Klein, K, McGovern, A, Kuret, T, Houtman, M, Burja, B, Micheroli, R, Shi, C, Marks, M, Filer, A, Buckley, C D, Orozco, G, Distler, O, Morris, A P, Martin, P, Eyre, S & Ospelt, C 2021, ' Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability ', Genome Biology, vol. 22, no. 1, 247, pp. 247 . https://doi.org/10.1186/s13059-021-02460-6
Genome Biology, Vol 22, Iss 1, Pp 1-39 (2021)
Genome Biology
Subject Terms: Adult, Arthritis, Rheumatoid/genetics, Base Sequence, Chromatin/metabolism, Databases, Genetic, Enhancer Elements, Genetic/genetics, Epigenesis, Genetic/drug effects, Female, Fibroblasts/drug effects, Gene Regulatory Networks/drug effects, Genetic Predisposition to Disease, Genomics, Humans, Immunoglobulin J Recombination Signal Sequence-Binding Protein/genetics, Inheritance Patterns/genetics, Male, Middle Aged, Polymorphism, Single Nucleotide/genetics, Probability, Receptor, Interferon alpha-beta/metabolism, Receptors, Interferon/metabolism, Reproducibility of Results, Risk Factors, Synovial Membrane/pathology, Tumor Necrosis Factor alpha-Induced Protein 3/metabolism, Tumor Necrosis Factor-alpha/pharmacology, Young Adult, Fibroblast-like synoviocytes, Functional genomics, Rheumatoid arthritis, Stromal cells, 610 Medicine & health, 10051 Rheumatology Clinic and Institute of Physical Medicine, 1105 Ecology, Evolution, Behavior and Systematics, 1311 Genetics, 1307 Cell Biology, Biology (General), QH301-705.5, Genetics, QH426-470, musculoskeletal diseases, skin and connective tissue diseases, Research
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Authors: Handoko, L., Kaczkowski, B., Hon, C. C., Lizio, M., Wakamori, M., Matsuda, T., Ito, T., Jeyamohan, P., Sato, Y., Sakamoto, K., Yokoyama, S., Kimura, Hiroshi, Minoda, A., Umehara, T.
Source: Epigenetics. 13(No. 4):410-431
Subject Terms: Acetylation/drug effects, Animals, Azepines/*pharmacology, Carcinoma, Non-Small-Cell Lung/drug therapy/*genetics/metabolism, Cell Line, Tumor, Chromatin/metabolism, Gene Expression Regulation, Neoplastic/drug effects, Histones/*chemistry/metabolism, Humans, Lung Neoplasms/drug therapy/*genetics/metabolism, Mice, Models, Molecular, Promoter Regions, Genetic/drug effects, Protein-Serine-Threonine Kinases/*metabolism, Proto-Oncogene Proteins c-myc/genetics, Transcription Factors, Transcription Initiation Site/drug effects, Triazoles/*pharmacology, Bet, Brd2, Cage, H4 hyperacetylation, Jq1, Chemistry, Histone H4, Transcription factor, Chromatin, Enhancer, Histone, biology.protein, biology, Bromodomain, Cell biology, Promoter, Transcriptional regulation, Cancer Research, Molecular Biology, Histone code, Cancer research
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http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100822105
Source:
PLOS Genetics, Vol. 16, No 5 (2020) P. e1008797
PLoS Genetics
PLoS genetics, vol. 16, no. 5, pp. e1008797
PLoS Genetics, Vol 16, Iss 5, p e1008797 (2020)
Subject Terms: ddc:580, ddc:590, Research Article, Biology and Life Sciences, Organisms, Eukaryota, Plants, Seedlings, Physical sciences, Physics, Electromagnetic radiation, Light, Ultraviolet radiation, Ultraviolet B, Visible Light, White Light, Genetics, Gene Expression, Gene Types, Regulator Genes, Gene Regulation, Transcriptional Control, Molecular Biology, Molecular Biology Techniques, Marker Genes, Research and Analysis Methods, Plant Science, Plant Anatomy, Fruit and Seed Anatomy, Plant Embryo Anatomy, Hypocotyl, Developmental Biology, Embryogenesis, Plant Embryogenesis, Plant Growth and Development, Plant Development, Arabidopsis/drug effects, Arabidopsis/genetics, Arabidopsis/metabolism, Arabidopsis Proteins/chemistry, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, Basic Helix-Loop-Helix Transcription Factors/chemistry, Basic Helix-Loop-Helix Transcription Factors/genetics, Basic Helix-Loop-Helix Transcription Factors/metabolism, Chromatin/metabolism, Chromosomal Proteins, Non-Histone/genetics, Chromosomal Proteins, Non-Histone/metabolism, DNA-Binding Proteins/chemistry, DNA-Binding Proteins/genetics, DNA-Binding Proteins/metabolism, Down-Regulation, Gene Expression Regulation, Plant/radiation effects, Protein Stability, Proteolysis, Transcription Factors/genetics, Transcription Factors/metabolism, Ubiquitin-Protein Ligases/genetics, Ubiquitin-Protein Ligases/metabolism, Ultraviolet Rays/adverse effects, QH426-470
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https://archive-ouverte.unige.ch/unige:136315
Authors: Chern Han Yong, Pär Nordlund, Lekshmy Sreekumar, Chris Soon Heng Tan, Xavier Bisteau, Philipp Kaldis, Yan Ting Lim, Johan Lengqvist, Lingyun Dai, Vinay Tergaonkar, Nayana Prabhu, Radoslaw M. Sobota, Ka Diam Go, Mert Burak Ozturk
Contributors: Tan, Chris Soon Heng, Go, Ka Diam, Bisteau, Xavier, Dai, Lingyun, Yong, Chern Han, Prabhu, Nayana, Ozturk, Mert Burak, Lim, Yan Ting, Sreekumar, Lekshmy, Lengqvist, Johan, Tergaonkar, Vinay, Kaldis, Philipp, Sobota, Radoslaw M, Nordlund, Pär
Source: Science, 359 (6380
Subject Terms: Multidisciplinary, Protein folding, S phase, Chemistry, Protein biosynthesis, Cell culture, Protein Array Analysis, Intracellular, Protein aggregation, Biophysics, Proteome, thermal proximity coaggregation, protein complexes, cells, Sciences bio-médicales et agricoles, Biologie, Biotechnologie, Technologie biochimique, Biologie cellulaire, Biochimie, Biophysique, Cell Line, Chromatin -- metabolism, Hot Temperature, Humans, Multiprotein Complexes -- metabolism, Protein Aggregates, Protein Aggregation, Pathological -- metabolism, Protein Biosynthesis, Protein Folding
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https://doi.org/10.1126/science.aan0346
Authors: Michael Lie-A-Ling, David R. Westhead, Salam A. Assi, Amber M L Emmett, Georges Lacaud, Rebecca Hannah, Nadine Obier, M. S. Vijayabaskar, Nisar A. Shar, Monika Lichtinger, Debbie K. Goode, Berthold Göttgens, Constanze Bonifer, Valerie Kouskoff, Fatin N. Zainul Abidin
Source:
PLoS Computational Biology
Vijayabaskar, M S, Goode, D K, Obier, N, Lichtinger, M, Emmett, A M L, Abidin, F N Z, Shar, N, Hannah, R, Assi, S A, Lie-A-Ling, M, Gottgens, B, Lacaud, G, Kouskoff, V, Bonifer, C & Westhead, D R 2019, ' Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells : An integrative approach using high-throughput datasets ', PLoS computational biology, vol. 15, no. 11, pp. e1007337 . https://doi.org/10.1371/journal.pcbi.1007337
PLoS Computational Biology, Vol 15, Iss 11, p e1007337 (2019)
Subject Terms: Research Article, Biology and Life Sciences, Genetics, Gene Expression, Cell Biology, Chromosome Biology, Chromatin, Epigenetics, Gene Regulation, Biochemistry, Proteins, DNA-binding proteins, Transcription Factors, Regulatory Proteins, Research and Analysis Methods, Mathematical and Statistical Techniques, Statistical Methods, Forecasting, Physical Sciences, Mathematics, Statistics, Transcriptional Control, DNA transcription, Computational Biology, Genome Analysis, Gene Prediction, Genomics, Computational Theory and Mathematics, Cellular and Molecular Neuroscience, Molecular Biology, Ecology, Modeling and Simulation, Ecology, Evolution, Behavior and Systematics, Transcription factor, Computational biology, Transcriptional regulation, Gene prediction, Regulation of gene expression, Regulatory sequence, Epigenomics, Biology, Animals, Cell Differentiation/genetics, Chromatin/metabolism, Databases, Genetic, Epigenesis, Genetic, Gene Expression Regulation/genetics, Genome, High-Throughput Screening Assays/methods, Macrophages/metabolism, Mice, Mouse Embryonic Stem Cells/metabolism, Myocytes, Cardiac/metabolism, Promoter Regions, Genetic, Regulatory Elements, Transcriptional/genetics, Regulatory Sequences, Nucleic Acid, Transcription Factors/metabolism, Biology (General), QH301-705.5, Macrophages, Myocytes, Cardiac, Cell Differentiation, Gene Expression Regulation, Regulatory Elements, Transcriptional, High-Throughput Screening Assays, Mouse Embryonic Stem Cells
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http://europepmc.org/articles/PMC6855567
Authors: Geneviève Almouzni, Iva Simeonova
Contributors: Dynamique de l'information génétique : bases fondamentales et cancer (DIG CANCER), Centre National de la Recherche Scientifique (CNRS)-Institut Curie [Paris]-Université Pierre et Marie Curie - Paris 6 (UPMC), Dynamique du noyau [Institut Curie], Institut Curie [Paris]-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Curie [Paris]-Centre National de la Recherche Scientifique (CNRS)
Source:
Trends in Molecular Medicine
Trends in Molecular Medicine, Elsevier, 2019, 25 (11), pp.933-935. ⟨10.1016/j.molmed.2019.09.003⟩
Subject Terms: CAF-1, chromatin reprogramming, histone H3 dynamics, metastasis, MESH: Chromatin / metabolism, Histone Chaperones / metabolism, Histones / metabolism, Humans, Neoplasm Metastasis / pathology, Neoplasms / pathology, [SDV]Life Sciences [q-bio], Molecular Biology, Molecular Medicine, Regulator, Metastasis, medicine.disease, medicine, Cancer research, Biology, Histone Chaperones, Histone H3, Cell fate determination, Invasive carcinoma, Transition (genetics)
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b371ef5620dd6af5ff66e06c01b2dd6
https://hal.archives-ouvertes.fr/hal-02371000
Authors: Pascal Giehr, Jie Lan, Konstantin K. Lepikhov, Joern Walter
Source:
Epigenetics & Chromatin
Epigenetics & Chromatin, 10 (1
Subject Terms: Research, Genetics, Molecular Biology, Histone H2A, Cell biology, Cancer epigenetics, Biology, Histone methyltransferase, Histone code, Histone methylation, Molecular biology, Histone H1, Epigenomics, Histone H3, Biologie moléculaire, Biologie, Animals, Chromatin -- metabolism, CpG Islands, DNA Methylation, Histones -- genetics -- metabolism, Mice, Mutagenesis, Site-Directed, Phosphorylation, Sequence Analysis, DNA, Serine -- metabolism, Threonine -- metabolism, Zygote -- cytology -- metabolism
File Description: 1 full-text file(s): application/pdf
Access URL: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7211a294fc56d7658fda0d39a79e136
Authors: Luis Aragón, Mohammad M. Karimi, Pilar Gutiérrez-Escribano, Francisco Antequera, Mar Sánchez, Axel Cournac, Luciana Lazar-Stefanita, Jonay García-Luis, Adam Jarmuz, Romain Koszul, Marian Dore, Holger B. Kramer, Sara Serrate González, Alicia García, Alex Montoya, Agnès Thierry
Contributors: Wellcome Trust, Medical Research Council (UK), European Commission, European Research Council, Agence Nationale de la Recherche (France), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), MRC London Institute of Medical Sciences (LMC), Régulation spatiale des Génomes - Spatial Regulation of Genomes, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Instituto de Biología Funcional y Genómica [Salamanca, Spain] (IBFG), Universidad de Salamanca-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), The work in the L.A. laboratory was supported by a Wellcome Trust Senior Investigator award to L.A. (100955, ‘Functional dissection of mitotic chromatin’) and the London Institute of Medical Research (LMS), which receives its core funding from the UK Medical Research Council. This research was further supported by funding from The European Research Council (R.K.), Agence Nationale pour la Recherche (R.K.) and the the Spanish Ministerio de Economía, Industria y Competitividad (BFU2017-89622-P, F.A.)., We thank the members of the L.A., R.K. and P.A. laboratories for fruitful discussions and advice.
Source:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biology
Subject Terms: biological phenomena, cell phenomena, and immunity, Chromosome condensation, Chromatin remodelling, Nuclear organization, MESH: Cell Cycle Proteins / metabolism, MESH: Chromatin / metabolism, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: DNA-Binding Proteins / metabolism, MESH: High Mobility Group Proteins / metabolism, MESH: Protein Interaction Maps, MESH: Saccharomyces cerevisiae / cytology, MESH: Saccharomyces cerevisiae / metabolism, MESH: Saccharomyces cerevisiae Proteins / metabolism, MESH: Transcriptional Elongation Factors / metabolism, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Article, Molecular Biology, Structural Biology, Chromosome, Chromatin, Histone, biology.protein, biology, Cohesin, Metaphase, Nucleosome, Chromosome segregation, Chemistry, Establishment of sister chromatid cohesion, Cell biology
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff873f2a495cde66beec1322917ac14
http://hdl.handle.net/10261/203767
Authors: Gianna Aurora Palumbo, Christine Neuveut, Shogofa Mortaza, Romain Koszul, Pierrick Moreau, Martial Marbouty, Marc Lavigne, Agnès Thierry, Axel Cournac, Stefano Cairo
Contributors: Hépacivirus et Immunité innée, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Régulation spatiale des Génomes - Spatial Regulation of Genomes, XenTech [Évry], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Département de Virologie - Department of Virology, Institut Pasteur [Paris], This work was supported by funding to C.N. from the Agence Nationale de la Recherche sur le Sida et les Hépatites Virales (ANRS) and Fondation pour la Recherche sur le Cancer (ARC). This research was also supported by funding to R.K. from the European Research Council under the 7th and H2020 Framework Program (FP7/2007-2013, ERC grant agreement 260822 and H2020 ERC grant agreement DLV-771813), and from Agence Nationale pour la Recherche (MeioRec ANR-13-BSV6-0012). P.M. was supported by ANRS and Institut Carnot. This study makes use of data generated by the ENCODE Consortium and the ENCODE production laboratories., We thank C. Seeger and S. Urban for kindly providing cell lines used in this study. We thank the UTechS PBI (Imagopole)-DTPS/C2RT, part of the France-BioImaging infrastructure network supported by the ANR (ANR-10-INSB-04, Investments for theFuture), for the use of the Zeiss widefield apotome microscope., ANR-13-BSV6-0012,MeioRec,Dynamique chromosomique et recombinaison au cours de la méiose(2013), European Project: 260822,EC:FP7:ERC,ERC-2010-StG_20091118,DICIG(2011), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)
Source:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.4268. ⟨10.1038/s41467-018-06739-4⟩
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Subject Terms: Virus–host interactions, Hepatitis B virus, Chromatin, Adenovirus, MESH: Base Sequence, MESH: Chromatin / metabolism, MESH: Gene Expression Regulation, MESH: Genome, Human, MESH: Hep G2 Cells, MESH: Hepatitis B virus / physiology, MESH: Hepatocytes / virology, MESH: Humans, MESH: Models, Biological, MESH: Plasmids / metabolism, MESH: Trans-Activators / metabolism, MESH: Transcription Initiation Site, MESH: Transcription, Genetic, MESH: Up-Regulation / genetics, MESH: CpG Islands / genetics, MESH: DNA, Viral / genetics, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, viruses, lcsh:Science, lcsh:Q, Article, Science, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, DNA, chemistry.chemical_compound, chemistry, CpG site, Transcription factor, Cell biology, Genome, Transcription (biology), Biology, Gene, Enhancer
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https://hal-pasteur.archives-ouvertes.fr/pasteur-02866759
Authors: Guillaume Bossis, Xavier Gaume, Jack-Christophe Cossec, Anne Dejean, Claudia Chica, Alexandra Andrieux, Jacob-Sebastian Seeler, Sabela Búa Aguín, Han Li, Grégory Jouvion, Ilan Theurillat, Maria-Elena Torres-Padilla, Ane Iturbide
Contributors: Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Sorbonne Université (SU), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Plasticité cellulaire et Modélisation des Maladies / Cellular Plasticity and Disease Modelling, Helmholtz-Zentrum München (HZM), Neuropathologie expérimentale / Experimental neuropathology, Institut Pasteur [Paris]-Université de Paris (UP), Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), This work was supported by grants from European Research Council (Advanced Research Grant 294341), LNCC (Equipe labellisée), INCa (n°2017-1 PL BIO-05-IP-1), and Odyssey to A.D. and from Association pour la Recherche sur le Cancer (ARC) (PJA 20161205028) and Revive (Laboratoire d’Excellence Revive, Investissement d’Avenir, ANR-10-LABX- 73) to H.L. J-C.C. was supported by INCa, I.T. by MESR and FRM, and X.G. by the Helmholtz Association., ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), European Project: 294341,EC:FP7:ERC,ERC-2011-ADG_20110310,SUMOSTRESS(2013), Helmholtz Zentrum München = German Research Center for Environmental Health, Institut Pasteur [Paris]-Université Paris Cité (UPCité), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)
Source:
Cell Stem Cell
Cell Stem Cell, Cambridge, MA : Cell Press, 2018, 23 (5), pp.742-757.e8. ⟨10.1016/j.stem.2018.10.001⟩
Cell Stem Cell, 2018, 23 (5), pp.742-757.e8. ⟨10.1016/j.stem.2018.10.001⟩
Cell Stem Cell 23, 742-757.e8 (2018)
Cell Stem Cell, Cambridge, MA : Cell Press, 2018, 23 (5), pp.742--757 e8. ⟨10.1016/j.stem.2018.10.001⟩
Subject Terms: totipotency, embryonic stem cells, pluripotency, reprogramming, chromatin, transdifferentiation, cell fate change, SUMO, Dux, 2C-like cells, MESH: Animals, MESH: Cells, Cultured, MESH: Cellular Reprogramming, MESH: Chromatin / metabolism, MESH: Mice, MESH: Mice, Inbred C57BL, MESH: Mouse Embryonic Stem Cells / cytology, MESH: Mouse Embryonic Stem Cells / metabolism, MESH: Small Ubiquitin-Related Modifier Proteins / metabolism, MESH: Transcription Factors / metabolism, [SDV.BA]Life Sciences [q-bio]/Animal biology, embryonic structures, 2c-like Cells, Sumo, Cell Fate Change, Chromatin, Embryonic Stem Cells, Pluripotency, Reprogramming, Totipotency, Transdifferentiation, Cell Biology, Genetics, Molecular Medicine, SUMO protein, Induced pluripotent stem cell, Embryonic stem cell, KLF4, SOX2, Cell biology, Cellular differentiation, Biology, 2C-like cells Dux Sumo cell fate change chromatin embryonic stem cells pluripotency reprogramming totipotency transdifferentiation, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
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https://hal-pasteur.archives-ouvertes.fr/pasteur-02869159
Authors: Miguel Rivera, Angela Volorio, Nicolo Riggi, Gaylor Boulay, Ivan Stamenkovic, Liliane C. Broye, Sowmya Iyer
Source: Genes & development, vol. 32, no. 15-16, pp. 1008-1019
Subject Terms: Animals, Bone Neoplasms/genetics, Bone Neoplasms/metabolism, Bone Neoplasms/pathology, Cells, Cultured, Chromatin/metabolism, Enhancer Elements, Genetic, Gene Expression Regulation, Neoplastic, Gene Silencing, Homeodomain Proteins/biosynthesis, Homeodomain Proteins/genetics, Humans, Mesenchymal Stromal Cells/metabolism, Mice, Microsatellite Repeats, Oncogene Proteins, Fusion/metabolism, Proto-Oncogene Protein c-fli-1/metabolism, RNA, Untranslated/biosynthesis, RNA-Binding Protein EWS/metabolism, Sarcoma, Ewing/genetics, Sarcoma, Ewing/metabolism, Sarcoma, Ewing/pathology, Transcription Factors/biosynthesis, Transcription Factors/genetics, Transcription, Genetic, Tumor Cells, Cultured, EWS-FLI1, Ewing sarcoma, enhancer therapy, epigenetics, epigenome editing, pediatric cancer, Developmental Biology, Genetics, Epigenome editing, Gene silencing, Gene expression, Gene, Epigenome, Enhancer, Regulation of gene expression, Biology, Computational biology, Chromatin, Research Paper
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https://serval.unil.ch/resource/serval:BIB_491F4BB08145.P001/REF.pdf
Authors: Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, Hiroshi, Ohkawa, Y., Kurumizaka, H.
Source: Biochemistry. 56(No. 16):2184-2196
Subject Terms: Chromatin/metabolism, Crystallography, X-Ray, Histones/*chemistry/genetics/metabolism, Humans, Protein Conformation, Protein Isoforms/*chemistry, Biochemistry, Histone H1, Chromatosome, Linker DNA, Histone H3, Histone code, Nucleosome, Histone methylation, Histone octamer, Biology
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http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100758879
Authors: Loviglio, M N, Leleu, M, Männik, K, Passeggeri, M, Giannuzzi, G, van der Werf, I, Waszak, S M, Zazhytska, M, Roberts-Caldeira, I, Gheldof, N, Migliavacca, E, Alfaiz, A A, Hippolyte, L, Maillard, A M, Loviglio, Maria Nicla, Männik, Katrin, van der Werf, Ilse, Giannuzzi, Giuliana, Zazhytska, Marianna, Gheldof, Nele, Migliavacca, Eugenia, Alfaiz, Ali A, Roberts-Caldeira, Inês, Hippolyte, Loyse, Maillard, Anne M, Ferrarini, Alessandra, Butschi, Florence Niel, Conrad, Bernard, Addor, Marie-Claude, Belfiore, Marco, Roetzer, Katharina, Dijck, Anke Van, Blaumeiser, Bettina, Kooy, Frank, Roelens, Filip, Dheedene, Annelies, Chiaie, Barbara Delle, Menten, Björn, Oostra, Ann, Caberg, Jean-Hubert, Carter, Melissa, Kellam, Barbara, Stavropoulos, Dimitri J, Marshall, Christian, Scherer, Stephen W, Weksberg, Rosanna, Cytrynbaum, Cheryl, Bassett, Anne, Lowther, Chelsea, Gillis, Jane, MacKay, Sara, Bache, Iben, Ousager, Lilian B, Smerdel, Maja Patricia, Graakjaer, Jesper, Kjaergaard, Susanne, Metspalu, Andres, Mathieu, Michele, Bonneau, Dominique, Guichet, Agnes, Parent, Philippe, Férec, Claude, Gerard, Marion, Plessis, Ghislaine, Lespinasse, James, Masurel, Alice, Marle, Nathalie, Faivre, Laurence, Callier, Patrick, Layet, Valerie, Meur, Nathalie Le, Le Goff, Céline, Duban-Bedu, Bénédicte, Sukno, Sylvie, Boute, Odile, Andrieux, Joris, Blanchet, Patricia, Geneviève, David, Puechberty, Jacques, Schneider, Anouck, Leheup, Bruno, Jonveaux, Philippe, Mercier, Sandra, David, Albert, Le Caignec, Cédric, de Pontual, Loic, Pipiras, Eva, Jacquette, Aurelia, Keren, Boris, Gilbert-Dussardier, Brigitte, Bilan, Frederic, Goldenberg, Alice, Chambon, Pascal, Toutain, Annick, Till, Marianne, Sanlaville, Damien, Leube, Barbara, Royer-Pokora, Brigitte, Grabe, Hans Jörgen, Schmidt, Carsten Oliver, Schurmann, Claudia, Homuth, Georg, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Bernardini, Laura, Novelli, Antonio, Micale, Lucia, Merla, Giuseppe, Zollino, Marcella, Mari, Francesca, Rizzo, Caterina Lo, Renieri, Alessandra, Silengo, Margherita, Vulto-van Silfhout, Anneke T, Schouten, Meyke, Pfundt, Rolph, de Leeuw, Nicole, Vansenne, Fleur, Maas, Saskia M, Barge-Schaapveld, Daniela QCM, Knegt, Alida C, Stadheim, Barbro, Rodningen, Olaug, Houge, Gunnar, Price, Sue, Hawkes, Lara, Campbell, Carolyn, Kini, Usha, Vogt, Julie, Walters, Robin, Blakemore, Alexandra, Gusella, James F, Shen, Yiping, Scott, Daryl, Bacino, Carlos A, Tsuchiya, Karen, Ladda, Roger, Sell, Susan, Asamoah, Alexander, Hamati, Aline I, Rosenfeld, Jill A, Shaffer, Lisa G, Mitchell, Elyse, Hodge, Jennelle C, Beckmann, Jacques S, Jacquemont, Sébastien, Reymond, Alexandre, Ewans, Lisa J, Mowat, David, Walker, Jan, Amor, David J, Esch, Hilde Van, Leroy, Patricia, Bamforth, John-Steven, Babu, Deepti, Isidor, Bertrand, DiDonato, Nataliya, Hackmann, Karl, Passeggeri, Marzia, Haeringen, Arie van, Smith, Rosemarie, Ellingwood, Sara, Farber, Darren M, Puri, Vinay, Zadeh, Neda, Weaver, David D, Miller, Mandy, Wilks, Timothy, Jorgez, Carolina J, Lafayette, DeeDee, Van Dijck, A, Kooy, R F, Sanlaville, D, Rosenfeld, J A, Shaffer, L G, Andrieux, J, Marshall, C, Scherer, S W, Shen, Y, Gusella, J F, Thorsteinsdottir, U, Thorleifsson, G, Dermitzakis, E T, Deplancke, B, Beckmann, J S, Rougemont, J, Jacquemont, S, Reymond, A
Contributors: Other departments, Human Genetics, CABERG, Jean-Hubert, Blaumeiser, Bettina, 2p15 Consortium, 16p11.2 Consortium, Loviglio, M.N., Männik, K., van der Werf, I., Giannuzzi, G., Zazhytska, M., Gheldof, N., Migliavacca, E., Alfaiz, A.A., Roberts-Caldeira, I., Hippolyte, L., Maillard, A.M., Ferrarini, A., Butschi, F.N., Conrad, B., Addor, M.C., Belfiore, M., Roetzer, K., Dijck, A.V., Blaumeiser, B., Kooy, F., Roelens, F., Dheedene, A., Chiaie, B.D., Menten, B., Oostra, A., Caberg, J.H., Carter, M., Kellam, B., Stavropoulos, D.J., Marshall, C., Scherer, S.W., Weksberg, R., Cytrynbaum, C., Bassett, A., Lowther, C., Gillis, J., MacKay, S., Bache, I., Ousager, L.B., Smerdel, M.P., Graakjaer, J., Kjaergaard, S., Metspalu, A., Mathieu, M., Bonneau, D., Guichet, A., Parent, P., Férec, C., Gerard, M., Plessis, G., Lespinasse, J., Masurel, A., Marle, N., Faivre, L., Callier, P., Layet, V., Meur, N.L., Le Goff, C., Duban-Bedu, B., Sukno, S., Boute, O., Andrieux, J., Blanchet, P., Geneviève, D., Puechberty, J., Schneider, A., Leheup, B., Jonveaux, P., Mercier, S., David, A., Le Caignec, C., de Pontual, L., Pipiras, E., Jacquette, A., Keren, B., Gilbert-Dussardier, B., Bilan, F., Goldenberg, A., Chambon, P., Toutain, A., Till, M., Sanlaville, D., Leube, B., Royer-Pokora, B., Grabe, H.J., Schmidt, C.O., Schurmann, C., Homuth, G., Thorleifsson, G., Thorsteinsdottir, U., Bernardini, L., Novelli, A., Micale, L., Merla, G., Zollino, M., Mari, F., Rizzo, C.L., Renieri, A., Silengo, M., Vulto-van Silfhout, A.T., Schouten, M., Pfundt, R., de Leeuw, N., Vansenne, F., Maas, S.M., Barge-Schaapveld, D.Q., Knegt, A.C., Stadheim, B., Rodningen, O., Houge, G., Price, S., Hawkes, L., Campbell, C., Kini, U., Vogt, J., Walters, R., Blakemore, A., Gusella, J.F., Shen, Y., Scott, D., Bacino, C.A., Tsuchiya, K., Ladda, R., Sell, S., Asamoah, A., Hamati, A.I., Rosenfeld, J.A., Shaffer, L.G., Mitchell, E., Hodge, J.C., Beckmann, J.S., Jacquemont, S., Reymond, A., Ewans, L.J., Mowat, D., Walker, J., Amor, D.J., Esch, H.V., Leroy, P., Bamforth, J.S., Babu, D., Isidor, B., DiDonato, N., Hackmann, K., Passeggeri, M., Haeringen, A.V., Smith, R., Ellingwood, S., Farber, D.M., Puri, V., Zadeh, N., Weaver, D.D., Miller, M., Wilks, T., Jorgez, C.J., Lafayette, D.
Source:
Ousager, L B & 2p15 Consortium 2017, ' Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes ', Molecular Psychiatry, vol. 22, no. 6, pp. 836-849 . https://doi.org/10.1038/mp.2016.84
Molecular psychiatry, 22(6), 836-849. Nature Publishing Group
Molecular Psychiatry
Molecular psychiatry
Molecular Psychiatry, vol. 22, no. 6, pp. 836-849
Molecular Psychiatry, 22, 836-849
Molecular Psychiatry, Vol. 22, No 6 (2017) pp. 836-849
Subject Terms: Adolescent, Adult, Aged, Autism Spectrum Disorder/genetics, Autistic Disorder/genetics, Body Mass Index, Child, Child, Preschool, Chromatin/metabolism, Chromosome Deletion, Chromosome Duplication, Chromosome Mapping/methods, Chromosomes, Human, Pair 16/genetics, DNA Copy Number Variations/genetics, Female, Humans, In Situ Hybridization, Fluorescence, Infant, Intellectual Disability/genetics, Male, Megalencephaly/genetics, Microcephaly/genetics, Middle Aged, Obesity/genetics, Phenotype, Autism Spectrum Disorder, Autistic Disorder, Chromatin, Chromosome Mapping, Chromosomes, Human, Pair 16, DNA Copy Number Variations, Intellectual Disability, Megalencephaly, Microcephaly, Obesity, Molecular Biology, Psychiatry and Mental Health, Cellular and Molecular Neuroscience, Settore MED/03 - GENETICA MEDICA, Original Article, Life sciences, Genetics & genetic processes, Sciences du vivant, Génétique & processus génétiques, Chemistry, Biology, Human medicine, Psychiatry and Mental health, Genetics, Gene, Copy-number variation, Locus (genetics), Fluorescence in situ hybridization, medicine.diagnostic_test, medicine, Gene duplication, medicine.disease, ddc:576.5
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Authors: Matsumura, Y., Nakaki, R., Inagaki, T., Yoshida, A., Kano, Y., Kimura, Hiroshi, Tanaka, T., Tsutsumi, S., Nakao, M., Doi, T., Fukami, K., Osborne, T. F., Kodama, T., Aburatani, H., Sakai, J.
Source: Molecular Cell. 60(4):584-596
Subject Terms: Cell Biology, Molecular Biology, environment and public health, Histone, biology.protein, biology, Chromatin, Cellular differentiation, Bivalent chromatin, Transcription factor, DNA methylation, CEBPA, Histone methylation, Molecular biology, 3T3 Cells, Adipocytes/*cytology/physiology, Animals, CCAAT-Enhancer-Binding Proteins/*metabolism, Cell Differentiation, Cell Lineage, Cells, Cultured, Chromatin/metabolism, DNA Methylation, Histone-Lysine N-Methyltransferase/metabolism, Histones/chemistry/*genetics, Mesenchymal Stromal Cells/cytology/physiology, Mice, PPAR gamma/*metabolism, Protein Structure, Tertiary, H3K27me3, H3K4me3, H3K9me3, RNA polymerase II, adipogenesis, bivalent chromatin domains, epigenome, gene-body methylation, lineage commitment
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