Showing 1 - 14 results of 14 for search '"Beabout K"', query time: 1.11s Refine Results
1
Academic Journal
Incoherent merger network for robust ratiometric gene expression response.

Authors: Kwon U; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Huang HH; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Chávez JL; 711th Human Performance Wing, Air Force Research Laboratory, Wright Patterson Air Force Base, OH, USA., Beabout K; 711th Human Performance Wing, Air Force Research Laboratory, Wright Patterson Air Force Base, OH, USA.; UES, Inc., Dayton, OH, USA., Harbaugh S; 711th Human Performance Wing, Air Force Research Laboratory, Wright Patterson Air Force Base, OH, USA., Del Vecchio D; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, USA.

Source: Nucleic acids research [Nucleic Acids Res] 2023 Apr 11; Vol. 51 (6), pp. 2963-2973.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

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2
Academic Journal
Detection of Bile Acids in Complex Matrices Using a Transcription Factor-Based Biosensor.

Authors: Beabout K; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States.; UES, Inc., Dayton, Ohio 45432, United States., Ehrenworth Breedon AM; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States.; UES, Inc., Dayton, Ohio 45432, United States., Blum SM; U.S. Army Combat Capabilities Development Command Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010, United States., Miklos AE; U.S. Army Combat Capabilities Development Command Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010, United States., Lux MW; U.S. Army Combat Capabilities Development Command Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010, United States., Chávez JL; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States., Goodson MS; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States.

Source: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2023 Sep 11; Vol. 9 (9), pp. 5151-5162. Date of Electronic Publication: 2022 Dec 07.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-9878 (Electronic) Linking ISSN: 23739878 NLM ISO Abbreviation: ACS Biomater Sci Eng Subsets: MEDLINE

MeSH Terms: Bile Acids and Salts* , Transcription Factors*/genetics, Humans ; Gene Expression Regulation ; Biomarkers ; Feces

3
Academic Journal
Optimization of Heavy Metal Sensors Based on Transcription Factors and Cell-Free Expression Systems.

Authors: Beabout K; UES, Inc., Dayton, Ohio 45432, United States.; Air Force Research Laboratory, 711th Human Performance Wing, Wright-Patterson Air Force Base, Dayton, Ohio 45433, United States., Bernhards CB; Excet, Inc., 6225 Brandon Avenue #360, Springfield, Virginia 22150, United States.; U.S. Army Combat Capabilities Development Command Chemical Biological Center, 8198 Blackhawk Road, Aberdeen Proving Ground, Maryland 21010, United States., Thakur M; Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, D.C. 20375, United States.; College of Science, George Mason University, Fairfax, Virginia 22030, United States., Turner KB; Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, D.C. 20375, United States., Cole SD; U.S. Army Combat Capabilities Development Command Chemical Biological Center, 8198 Blackhawk Road, Aberdeen Proving Ground, Maryland 21010, United States., Walper SA; Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, D.C. 20375, United States., Chávez JL; Air Force Research Laboratory, 711th Human Performance Wing, Wright-Patterson Air Force Base, Dayton, Ohio 45433, United States., Lux MW; U.S. Army Combat Capabilities Development Command Chemical Biological Center, 8198 Blackhawk Road, Aberdeen Proving Ground, Maryland 21010, United States.

Source: ACS synthetic biology [ACS Synth Biol] 2021 Nov 19; Vol. 10 (11), pp. 3040-3054. Date of Electronic Publication: 2021 Nov 01.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

MeSH Terms: Cell-Free System/*metabolism , Metals, Heavy/*metabolism , Transcription Factors/*metabolism, Bacteria/metabolism ; DNA/metabolism ; Plasmids/metabolism

4
Academic Journal
Impact of Porous Matrices and Concentration by Lyophilization on Cell-Free Expression.

Authors: Blum SM; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States., Lee MS; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States., Mgboji GE; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee 37830-6209, United States., Funk VL; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States., Beabout K; UES, Inc., Dayton, Ohio 45432, United States.; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States., Harbaugh SV; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States., Roth PA; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States.; DCS Corporation, 4696 Millenium Drive, Suite 450, Belcamp, Maryland 21017, United States., Liem AT; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States.; DCS Corporation, 4696 Millenium Drive, Suite 450, Belcamp, Maryland 21017, United States., Miklos AE; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States., Emanuel PA; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States., Walper SA; Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, District of Columbia 20375, United States., Chávez JL; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, United States., Lux MW; United States Army Combat Capabilities Development Command Chemical Biological Center. 8198 Blackhawk Road, APG, Aberdeen, Maryland 21010, United States.

Source: ACS synthetic biology [ACS Synth Biol] 2021 May 21; Vol. 10 (5), pp. 1116-1131. Date of Electronic Publication: 2021 Apr 12.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

MeSH Terms: Paper*, Cellulose/*chemistry , Hydrogels/*chemistry , Quartz/*chemistry, Biosensing Techniques/methods ; Cell-Free System ; Cross-Linking Reagents/chemistry ; Freeze Drying ; Porosity

5
Academic Journal
Daptomycin Resistance in Enterococcus faecium Can Be Delayed by Disruption of the LiaFSR Stress Response Pathway.

Authors: Prater AG; Department of BioSciences, Rice University, Houston, Texas, USA., Mehta HH; Department of BioSciences, Rice University, Houston, Texas, USA., Beabout K; Department of BioSciences, Rice University, Houston, Texas, USA., Supandy A; Department of BioSciences, Rice University, Houston, Texas, USA., Miller WR; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.; Center for Infectious Diseases, UTHealth School of Public Health, Houston, Texas, USA., Tran TT; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.; Center for Infectious Diseases, UTHealth School of Public Health, Houston, Texas, USA., Arias CA; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.; Center for Infectious Diseases, UTHealth School of Public Health, Houston, Texas, USA.; Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, Bogotá, Colombia.; Department of Microbiology and Molecular Genetics, UTHealth McGovern Medical School, Houston, Texas, USA., Shamoo Y; Department of BioSciences, Rice University, Houston, Texas, USA shamoo@rice.edu.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Mar 18; Vol. 65 (4). Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH Terms: Daptomycin*/pharmacology , Enterococcus faecium*/genetics , Gram-Positive Bacterial Infections*, Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Drug Resistance, Bacterial/genetics ; Humans ; Microbial Sensitivity Tests

6
Academic Journal
Acinetobacter baumannii Repeatedly Evolves a Hypermutator Phenotype in Response to Tigecycline That Effectively Surveys Evolutionary Trajectories to Resistance.

Authors: Hammerstrom TG; Department of Biosciences, Rice University, Houston, Texas, United States of America., Beabout K; Department of Biosciences, Rice University, Houston, Texas, United States of America., Clements TP; Department of Biosciences, Rice University, Houston, Texas, United States of America., Saxer G; Department of Biosciences, Rice University, Houston, Texas, United States of America., Shamoo Y; Department of Biosciences, Rice University, Houston, Texas, United States of America.

Source: PloS one [PLoS One] 2015 Oct 21; Vol. 10 (10), pp. e0140489. Date of Electronic Publication: 2015 Oct 21 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

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7
Academic Journal
Quantification of Interlaboratory Cell-Free Protein Synthesis Variability.

Authors: Cole SD; US Army Combat Capabilities Development Command Chemical Biological Center . 8198 Blackhawk Road , APG , Maryland 21010 , United States.; Excet, Inc. , 6225 Brandon Avenue #360 , Springfield , Virginia 22150 , United States., Beabout K; UES, Inc. , Dayton , Ohio 45432 , United States.; Air Force Research Laboratory , 711th Human Performance Wing , Wright-Patterson Air Force Base , Ohio 45433 , United States., Turner KB; Naval Research Laboratory , 4555 Overlook Avenue SW , Washington, D.C. 20375 , United States., Smith ZK; UES, Inc. , Dayton , Ohio 45432 , United States.; Air Force Research Laboratory , 711th Human Performance Wing , Wright-Patterson Air Force Base , Ohio 45433 , United States., Funk VL; US Army Combat Capabilities Development Command Chemical Biological Center . 8198 Blackhawk Road , APG , Maryland 21010 , United States., Harbaugh SV; Air Force Research Laboratory , 711th Human Performance Wing , Wright-Patterson Air Force Base , Ohio 45433 , United States., Liem AT; DCS Corporation , 100 Walter Ward Blvd, Suite 100 , Abingdon , Maryland 21009 , United States., Roth PA; DCS Corporation , 100 Walter Ward Blvd, Suite 100 , Abingdon , Maryland 21009 , United States., Geier BA; Air Force Research Laboratory , 711th Human Performance Wing , Wright-Patterson Air Force Base , Ohio 45433 , United States., Emanuel PA; US Army Combat Capabilities Development Command Chemical Biological Center . 8198 Blackhawk Road , APG , Maryland 21010 , United States., Walper SA; Naval Research Laboratory , 4555 Overlook Avenue SW , Washington, D.C. 20375 , United States., Chávez JL; Air Force Research Laboratory , 711th Human Performance Wing , Wright-Patterson Air Force Base , Ohio 45433 , United States., Lux MW; US Army Combat Capabilities Development Command Chemical Biological Center . 8198 Blackhawk Road , APG , Maryland 21010 , United States.

Source: ACS synthetic biology [ACS Synth Biol] 2019 Sep 20; Vol. 8 (9), pp. 2080-2091. Date of Electronic Publication: 2019 Sep 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

MeSH Terms: Cell-Free System*, Proteins/*metabolism, DNA/metabolism ; Laboratories/standards ; Protein Biosynthesis ; Reproducibility of Results

8
Academic Journal
The Essential Role of Hypermutation in Rapid Adaptation to Antibiotic Stress.

Authors: Mehta HH; Department of Biosciences, Rice University, Houston, Texas, USA., Prater AG; Department of Biosciences, Rice University, Houston, Texas, USA., Beabout K; Department of Biosciences, Rice University, Houston, Texas, USA., Elworth RAL; Department of Computer Science, Rice University, Houston, Texas, USA., Karavis M; U.S. Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland, USA., Gibbons HS; U.S. Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland, USA., Shamoo Y; Department of Biosciences, Rice University, Houston, Texas, USA shamoo@rice.edu.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 Jun 24; Vol. 63 (7). Date of Electronic Publication: 2019 Jun 24 (Print Publication: 2019).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH Terms: Adaptation, Physiological/*drug effects , Anti-Bacterial Agents/*pharmacology , Mutation/*drug effects, Adaptation, Physiological/genetics ; Alleles ; Bacterial Proteins/genetics ; Colistin/pharmacology ; Evolution, Molecular ; Genome, Bacterial/genetics ; Mutation/genetics ; Mutation Rate ; Phenotype ; Phylogeny ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/genetics

9
Academic Journal
Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics.

Authors: Beabout K; Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., McCurry MD; Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Mehta H; Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Shah AA; Department of Chemistry, BioScience Research Collaborative, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Pulukuri KK; Department of Chemistry, BioScience Research Collaborative, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Rigol S; Department of Chemistry, BioScience Research Collaborative, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Wang Y; Department of Chemistry, BioScience Research Collaborative, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Nicolaou KC; Department of Chemistry, BioScience Research Collaborative, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Shamoo Y; Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States.

Source: ACS infectious diseases [ACS Infect Dis] 2017 Nov 10; Vol. 3 (11), pp. 854-865. Date of Electronic Publication: 2017 Sep 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

MeSH Terms: Anti-Bacterial Agents/*pharmacology , Pyrrolidinones/*pharmacology , Transaminases/*drug effects, Anti-Bacterial Agents/chemistry ; Biological Evolution ; Drug Resistance, Multiple, Bacterial ; Genetic Variation ; Genome, Bacterial ; Microbial Sensitivity Tests ; Molecular Structure ; Oxygen Consumption ; Pyrrolidinones/chemistry ; Structure-Activity Relationship ; Transaminases/genetics

10
Academic Journal
Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents.

Authors: Nicolaou KC; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Pulukuri KK; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Rigol S; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Buchman M; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Shah AA; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Cen N; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., McCurry MD; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Beabout K; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Shamoo Y; Department of Chemistry, BioScience Research Collaborative and ‡Department of BioSciences, Rice University , 6100 Main Street, Houston, Texas 77005, United States.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2017 Nov 08; Vol. 139 (44), pp. 15868-15877. Date of Electronic Publication: 2017 Oct 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH Terms: Anti-Bacterial Agents/*chemical synthesis , Anti-Bacterial Agents/*pharmacology , Lactones/*chemical synthesis , Lactones/*pharmacology , Pyrazoles/*chemical synthesis , Pyrazoles/*pharmacology, Anti-Bacterial Agents/chemistry ; Chemistry Techniques, Synthetic/methods ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacterial Infections/drug therapy ; Humans ; Lactones/chemistry ; Microbial Sensitivity Tests ; Pyrazoles/chemistry ; Stereoisomerism ; Structure-Activity Relationship

11
Academic Journal
Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis of (-)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents.

Authors: Nicolaou KC; Department of Chemistry, BioScience Research Collaborative and ‡Department of Biochemistry and Cell Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Liu G; Department of Chemistry, BioScience Research Collaborative and ‡Department of Biochemistry and Cell Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Beabout K; Department of Chemistry, BioScience Research Collaborative and ‡Department of Biochemistry and Cell Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States., McCurry MD; Department of Chemistry, BioScience Research Collaborative and ‡Department of Biochemistry and Cell Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Shamoo Y; Department of Chemistry, BioScience Research Collaborative and ‡Department of Biochemistry and Cell Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2017 Mar 15; Vol. 139 (10), pp. 3736-3746. Date of Electronic Publication: 2017 Mar 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH Terms: Anthracenes/*chemistry , Anti-Bacterial Agents/*pharmacology , Tetracyclines/*pharmacology, Alkylation ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Crystallography, X-Ray ; Models, Molecular ; Molecular Structure ; Stereoisomerism ; Tetracyclines/chemical synthesis ; Tetracyclines/chemistry

12
Academic Journal
Rampant Parasexuality Evolves in a Hospital Pathogen during Antibiotic Selection.

Authors: Beabout K; Department of BioSciences, Rice University., Hammerstrom TG; Department of BioSciences, Rice University., Wang TT; Department of BioSciences, Rice University., Bhatty M; Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston., Christie PJ; Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston., Saxer G; Department of BioSciences, Rice University., Shamoo Y; Department of BioSciences, Rice University shamoo@rice.edu.

Source: Molecular biology and evolution [Mol Biol Evol] 2015 Oct; Vol. 32 (10), pp. 2585-97. Date of Electronic Publication: 2015 Jun 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-1719 (Electronic) Linking ISSN: 07374038 NLM ISO Abbreviation: Mol Biol Evol Subsets: MEDLINE

MeSH Terms: Hospitals*, Anti-Bacterial Agents/*pharmacology , Drug Resistance, Microbial/*genetics , Enterococcus faecalis/*genetics, ATP-Binding Cassette Transporters/metabolism ; Adaptation, Physiological/drug effects ; Alleles ; Bacterial Proteins/metabolism ; Base Sequence ; Chromosomes, Bacterial/genetics ; Directed Molecular Evolution ; Drug Resistance, Microbial/drug effects ; Enterococcus faecalis/drug effects ; Gene Dosage ; Humans ; Minocycline/analogs & derivatives ; Minocycline/pharmacology ; Molecular Sequence Data ; Mutagenesis, Insertional/genetics ; Phenotype ; Regulatory Sequences, Nucleic Acid/genetics ; Ribosomes/drug effects ; Ribosomes/metabolism ; Sequence Deletion ; Tigecycline ; Treatment Outcome

13
Academic Journal
The ribosomal S10 protein is a general target for decreased tigecycline susceptibility.

Authors: Beabout K; Department of BioSciences, Rice University, Houston, Texas, USA., Hammerstrom TG; Department of BioSciences, Rice University, Houston, Texas, USA., Perez AM; Department of BioSciences, Rice University, Houston, Texas, USA., Magalhães BF; Department of BioSciences, Rice University, Houston, Texas, USA CAPES Foundation, Ministry of Education of Brazil, Brasilia, Brazil., Prater AG; Department of BioSciences, Rice University, Houston, Texas, USA., Clements TP; Department of BioSciences, Rice University, Houston, Texas, USA., Arias CA; Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical School at Houston, Houston, Texas, USA Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA Molecular Genetics and Antimicrobial Resistance Unit, Bogota, Colombia., Saxer G; Department of BioSciences, Rice University, Houston, Texas, USA., Shamoo Y; Department of BioSciences, Rice University, Houston, Texas, USA shamoo@rice.edu.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Sep; Vol. 59 (9), pp. 5561-6. Date of Electronic Publication: 2015 Jun 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH Terms: Anti-Bacterial Agents/*pharmacology , Minocycline/*analogs & derivatives, Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/metabolism ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacteria/metabolism ; Microbial Sensitivity Tests ; Minocycline/pharmacology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/metabolism ; Tigecycline

14
Academic Journal
Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation.

Authors: Nicolaou KC; Department of Chemistry, §Department of Biochemistry and Cell Biology, and ∥Department of Ecology and Evolutionary Biology, Rice University , 6100 Main Street, Houston, Texas 77005, United States., Hale CR, Nilewski C, Ioannidou HA, ElMarrouni A, Nilewski LG, Beabout K, Wang TT, Shamoo Y

Source: Journal of the American Chemical Society [J Am Chem Soc] 2014 Aug 27; Vol. 136 (34), pp. 12137-60. Date of Electronic Publication: 2014 Aug 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH Terms: Anti-Bacterial Agents/*chemical synthesis , Tetracyclines/*chemical synthesis, Alkylation ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Lewis Acids/chemistry ; Microbial Sensitivity Tests ; Molecular Structure ; Tetracyclines/chemistry ; Tetracyclines/pharmacology

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